Clinical trials: Skin Tests
Skin and Connective Tissue Diseases
A Psoriasis Plaque Test Trial With LEO 90100 Compared to Betesil® in Patients With Psoriasis Vulgaris
The purpose of this study is to evaluate the anti-psoriatic effect of LEO 90100 aerosol foam compared with Betesil® medicated plaster
- Trial name
- NCT02518048
- Testing
- LEO 90100 Aerosol foam, Betesil® 2.25 mg
- Where
- France
- Volunteers
- 35 people
- Sponsor
- LEO Pharma
Photoallergy
Evaluation of Potential Development of Photoallergic Skin Reaction After Use of MC2-01 Cream
This trial is a 6-week, Randomized study evaluating the potential of MC2-01 Cream to induce a photoallergic skin reaction in Healthy subjects, using a controlled photopatch test design.
- Trial name
- NCT03899064
- Testing
- Induction: Application of MC2-01 Cream, irradiation, Induction: Application of MC2-01 Cream, no irradiation, Induction: Applications of MC2-01 vehicle, irradiation
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- MC2 Therapeutics
Psoriasis Vulgaris
A 12 Day Study To Evaluate A Topical Drug To Treat Plaque Psoriasis
This is a vehicle and comparator controlled Proof of Mechanism (PoM) trial to evaluate the effect on psoriasis disease activity and safety of topically applied PF 06263276 in subjects with psoriasis vulgaris.
- Trial name
- NCT02193815
- Testing
- PF06263276, Vehicle, 2%Tofacitinib Ointment
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Pfizer
Hypersensitivity
Skin Prick Test of KeraStat® Cream
To evaluate the potential for a humoral reaction to KeraStat Cream compared to a predicate device using the skin prick test.
- Trial name
- NCT04058054
- Testing
- KeraStat® Cream, KeraStat Gel, Biafine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- KeraNetics, LLC
Skin Care
To Investigate Primary Irritation Potential of Four Skin Serum Products on Human Subjects Assessed by 24 Hour Patch Test
To assess the irritation potential of four prototype daily defense serum formulations after 24 (± 2) hours under semi-occlusive patch application to the skin of healthy volunteers.
- Trial name
- NCT03233009
- Testing
- Experimental Daily Defense Serum A, Experimental Daily Defense Serum C, Experimental Daily Defense Serum G
- Where
- 2 sites in Brazil
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Surgical Site Infection
Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances
Comparative study of antimicrobial effectiveness evaluation of of 26ml Project X, 10.5ml Project X, 5.1ml Project X and Prevantics Maxi swabstick following ASTM E1173 - Standard test method for evaluation of preoperative…
- Trial name
- NCT04218110
- Testing
- Isopropyl alcohol & Chlorhexidine Gluconate Antiseptic, Prevantics 3.15 % / 70 % Swabstick
- Where
- Romania
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Professional Disposables International, Inc.
Acne Vulgaris
Clinical Study to Test the Efficacy and Safety of Adapalene, 0.1%
The purpose of this study is to determine whether Adapalene, 0.1% is safe and effective in the treatment of Acne Vulgaris.
- Trial name
- NCT00599521
- Testing
- Adapalene lotion 0.1%, Adapalene Lotion Vehicle
- Where
- 34 sites in United States, Canada
- Volunteers
- 1,067 people
- Sponsor
- Galderma R&D
History of IgE Dependent Reaction to a Penicillin Product
Evaluation of Skin Testing Reagents for Penicillin Allergy
A self- or parent-reported history of penicillin allergy excludes approximately 10% of the US population from receiving penicillin (Kerr 1994, Kagy, Blaiss 1998, Solensky et al. 2000, Neugut et al. 2001).
- Trial name
- NCT01818336
- Testing
- Penicillin skin test kit
- Where
- 13 sites in United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- AllerQuest LLC
Hookworm Infection, Allergy
Development of a Skin Test for the Na-ASP-2 Hookworm Antigen
Na-ASP-2 is a protein expressed during the larval stage of the N. americanus hookworm life cycle. In a clinical study in previously hookworm-infected adults in Brazil, this protein induced urticarial reactions (rash) in a subset…
- Trial name
- NCT00603889
- Testing
- Na-ASP-2 Skin Test Reagent
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Dermatitis, Atopic
A Study in Patients With Atopic Eczema to Test How Effective BI 655130 is and How Well it is Tolerated
The primary objective of this trial is to investigate the safety, tolerability and efficacy of BI 655130 in patients with Atopic Dermatitis (AD) following repeated intravenous administrations compared to placebo.
- Trial name
- NCT03822832
- Testing
- BI 655130
- Where
- 23 sites in United States, Canada and 1 more
- Volunteers
- 51 people
- Sponsor
- Boehringer Ingelheim
Contact Dermatitis
Clinical Evaluation of T.R.U.E. TEST® : Safety and Efficacy
We propose an open, prospective, multi-center Phase III study to evaluate the diagnostic performance and safety of seven new T.R.U.E.
- Trial name
- NCT00640614
- Testing
- T.R.U.E. TEST® Skin Patch Test: Dose Response Allergens
- Where
- 5 sites in United States, Denmark
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Allerderm
Breast Cancer
Implantable Microdevice for In Vivo Drug Sensitivity Testing in Patients With Early Stage, HER2-Positive or Triple Negative Breast Cancer
The purpose of this study is to test the safety and feasibility of placing and removing a small device that contains anti-cancer drugs in a breast tumor of patients who plan on having breast surgery without treatment prior or…
- Trial name
- NCT02521363
- Testing
- KIBUR MICRODEVICE, anthracycline and taxane based chemotherapy
- Where
- 6 sites in United States
- Volunteers
- 11 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
S0500 Treatment Decision Making Based on Blood Levels of Tumor Cells for Metastatic Breast Cancer Treated With Chemo
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00382018
- Testing
- chemotherapy
- Where
- 296 sites in United States
- Volunteers
- 624 people
- Sponsor
- SWOG Cancer Research Network
Giant Cell Arteritis
KPL-301 for Subjects With Giant Cell Arteritis
The primary objective of the study is to evaluate the efficacy of mavrilimumab (KPL-301) versus placebo, co-administered with a 26-week corticosteroid taper, for maintaining sustained remission for 26 weeks in subjects with new…
- Trial name
- NCT03827018
- Testing
- mavrilimumab, prednisone
- Where
- 49 sites in United States, Australia and 13 more
- Volunteers
- 70 people
- Sponsor
- Kiniksa Pharmaceuticals, Ltd.
Yaws
Evaluation of a LAMP Assay for T. Pallidum. Pertenue
This is a diagnostic evaluation comparing the performance of real-time PCR performed at a national reference laboratory and a LAMP assay performed at a regional hospital for the diagnosis of yaws
- Trial name
- LAMP4YAWS (NCT04753788)
- Testing
- PCR, LAMP
- Where
- 3 sites in Cameroon, Côte d’Ivoire and 1 more
- Volunteers
- 563 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Herpes Labialis
Safety and Efficacy of Squaric Acid Dibutyl Ester for the Treatment of Herpes Labialis
Subjects with a history of recurrent herpes labialis will be sensitized with either 2% SADBE or placebo. Following this, subjects sensitized with 2% SADBE will received.2% sqauric acid or.5% squaric acid on their cold sore within…
- Trial name
- Squarex (NCT01971385)
- Testing
- Squaric Acid solution
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Acne Vulgaris
Clinical Study to Test the Efficacy and Safety of Adapalene, 0.1%
The purpose of this study is to determine whether Adapalene, 0.1% is safe and effective in the treatment of Acne Vulgaris.
- Trial name
- NCT00598832
- Testing
- Adapalene lotion 0.1%, Adapalene Lotion Vehicle
- Where
- 34 sites in United States, Canada
- Volunteers
- 1,075 people
- Sponsor
- Galderma R&D
Asthma
A Study of Efficacy of New Doses of Xolair to Protect From Allergen Challenge in Groups of Asthma Patients Defined by IgE Levels
This study was intended to demonstrate that patients with standard and high immunoglobulin E (IgE) levels can be protected from allergen induced broncho-constriction by Xolair
- Trial name
- NCT00624832
- Testing
- Xolair
- Where
- 6 sites in Germany, Netherlands and 1 more
- Volunteers
- 60 people
- Sponsor
- Novartis
Pain
Caring for Babies During the Newborn Screening Blood Test
Newborn infants have blood work procedures in their first days of life that cause pain, distress and physiological changes. Breastfeeding (BF), skin to skin care (SSC), or giving sweet solutions (sucrose or glucose) has been…
- Trial name
- NCT02608892
- Testing
- BSweet2Babies video
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Melanoma (Skin)
Skin Health Online for Melanoma: Better Risk Assessment
This study will have two phases, with an added usability test after Phase I and before Phase 2. Phase 1: Cognitive Interviews of materials in Spanish. Phase 2: Personalized Genomic Testing for Skin Cancer (PGT-SC).
- Trial name
- SOMBRA (NCT03130569)
- Testing
- Web-based Module Group
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of New Mexico