Clinical trials: Skin Thickness
Skin Thickness, Skin Stiffness
Effects of Vibration Therapy on Plantar Skin Properties
The goal of this clinical trial is to learn if there are changes in plantar skin surface in the first metatarsal head (M1) after getting local vibration treatments.
- Conditions
- Skin Thickness, Skin Stiffness, Microcirculation
- Trial name
- NCT07863843
- Testing
- Local vibration
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asia University
Donor Site Complication, Skin Graft Scar
A Single Center Trial of Donor Site Wound Dressings After Split Thickness Skin Grafting.
The goal of this clinical trial] is to compare different types of dressings used and there outcomes on STSG donor site wound. The main question[s] it aims to answer are: the effectiveness of different donor site dressings and…
- Trial name
- NCT06044519
- Testing
- different types of dressings
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Healthy
Phase I Study of Topical CRx-191 in Normal Healthy Volunteers
CRx-191 is a proprietary synergistic combination drug candidate being evaluated by CombinatoRx for topical psoriasis therapy. CRx-191 was identified via a proprietary screening assay for novel drug combinations demonstrating…
- Trial name
- NCT00544687
- Testing
- CRx-191, mometasone furoate, nortriptyline HCl
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zalicus
Wound of Skin, Wound Heal
Efficacy and Safety of 0.25% Timolol Gel in Enhancing Full Thickness Skin Grafts Healing and Cosmetic Outcomes
The use of topical beta-blockers, such as 0.25% timolol, in promoting wound healing is currently emerging in the academic literature.
- Conditions
- Wound of Skin, Wound Heal, Surgical Wound, Full Thickness Skin Graft Healing
- Trial name
- FTSG (NCT03579160)
- Testing
- 0.25% timolol gel with full-thickness skin grafts, Vaseline dressing
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Skin Transplantation
Post-market Clinical Follow-up Study for a CE Marked Wound Care Product (FibDex®)
FibDex® 2-2022 is a sponsored, post-marketing clinical follow-up (PMCF) study to monitor the clinical performance and safety of the CE marked product nanofibrillar cellulose (NFC) wound dressing, FibDex®, when used according to…
- Trial name
- NCT05666999
- Testing
- FibDex®, Suprathel, Aquacel Foam
- Where
- Finland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- UPM-Kymmene Corporation
Burns, Skin Graft Complications
Suprathel Versus Xeroform for the Management of Skin Graft Donor Sites
The investigators aim to study whether Suprathel, a synthetic temporary skin substitute developed by PolyMedics Innovations GmBH aids in the management of patient pain and wound healing when compared to the current standard…
- Conditions
- Burns, Skin Graft Complications, Skin; Deformity
- Trial name
- Suprathel (NCT04014400)
- Testing
- Suprathel or Xeroform donor site application
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Head and Neck Cancer, Surgery--Complications
Tumescence in HNC Skin Graft Reconstruction
Our primary objective is to determine if the use of tumescence has a meaningful effect on STSG uptake at the recipient site. This is an important outcome because poor graft uptake results in the need for prolonged local wound…
- Conditions
- Head and Neck Cancer, Surgery--Complications, Graft Failure
- Trial name
- NCT04967391
- Testing
- Tumescence During STSG Harvest
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy
Comparison of Skin Thickness Under Treatment With Pimecrolimus 1% Cream, Hydrocortisonacetat 1% Cream, Betamethasonvalerat 0,1% Cream and Clobetasol-17-propionat 0,05% Cream Assessed by Optical Coherence Tomography (OCT) and 20-MHZ Ultrasound
to compare the atrophogenic potentials of pimecrolimus 1% cream, hydrocortisonacetat 1% cream, betamethasonvalerat 0,1% cream and clobetasol-17-Propionat 0,05% cream
- Trial name
- OCT (NCT00655512)
- Testing
- pimecrolimus 1% cream, hydrocortisonacetat 1% cream, betamethasonvalerat 0,1% cream
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Nutritional Status, Nutrient Deficiency
Challenges in Achieving Adequate Dietary Status of Women
The aim of the study is to investigate the dietary habits of women of reproductive age (20-49 years). We aim to obtain epidemiological data on the intake and adequacy of key macronutrients and micronutrients, as well as to…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NutriFem (NCT06745817)
- Testing
- Assessement of nutritional status, Dermis density and thickness, Skin elasticity
- Where
- 3 sites in Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Takayasu's Arteritis, Giant Cell Arteritis
Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis
The purpose of this study is to evaluate the ability of contrast enhanced carotid ultrasound to serve as an indicator of disease activity in patients with Takayasu's arteritis or Giant Cell arteritis and to determine if patients…
- Conditions
- Takayasu's Arteritis, Giant Cell Arteritis, Arteritis, Vasculitis
- Trial name
- NCT01795456
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Wound of Skin, Wound Heal
Topical Collagen Powder for Healing of Acute Full-thickness Wounds
We have designed a pilot study to investigate the effect and potential utility of topical NuvagenTM (collagen powder) on the rate and quality of wound healing in healthy volunteers using the punch biopsy method.
- Trial name
- NCT03481907
- Testing
- Nuvagen Collagen Powder
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Adam Friedman
Dermis Density, Wrinkles
The Effect of 12-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters
The aim of the randomized, double-blind, placebo-controlled, one-period effectiveness study is to compare the effects of multiple-dose 12 weeks daily dietary supplementation with 10 g collagen alone or 5 g or 10 g of collagen in…
- Conditions
- Dermis Density, Wrinkles, Skin Hydration, Trans Epidermal Water Loss (TEWL)
- Trial name
- TO-COSKIN (NCT04988412)
- Testing
- Investigational product 1, Investigational product 2, Investigational product 3
- Where
- Slovenia
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Wounds and Injuries
Safety and Efficacy of AR/101 in Accelerating Re-epithelialization of Split Thickness Wounds
This clinical study will be a prospective, placebo-controlled, double-blind, randomized and centrally evaluated intra-individual comparative study to assess the safety and efficacy of AR/101 concomitantly administered with…
- Trial name
- NCT02602184
- Testing
- AR/101
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Arava Bio Tech Ltd.
Skin Rejuvenation, Laser
Comparative Effectiveness of Long-Pulsed 1064-nm Nd:YAG and Fractional CO₂ Laser in Skin Rejuvenation
Skin rejuvenation is an effort to improve skin condition from the signs of skin aging. Skin aging is a complex biological process influenced by intrinsic and extrinsic factors, leading to changes in the epidermis and dermis…
- Trial name
- NCT07467954
- Testing
- Fractional CO₂ laser, Long-pulsed 1064-nm Nd:YAG laser
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Traumatic Skin Loss, 2nd and 3rd Degree Burn, Post Tumour Excision - Raw Areas Undergoes Split- Thickness Skin Grafts
Evaluation of the Use of Minced Skin Grafts for Promoting Donor Site Wound Healing After Split-Thickness Skin Grafting
Split-thickness skin grafting (STSG) is one of the most commonly performed procedures to achieve wound closure. Most studies are concerned on improving the appearance of scars and shortening the healing time of the recipient…
- Trial name
- NCT06488612
- Testing
- Minced skin grafts for donor site
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Surgical Incisions
Prineo (Dermabond Protape) Versus Sutures for Full-thickness Surgical Incisions
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 subjects with full thickness surgical incisions.
- Trial name
- NCT00557947
- Testing
- Suture, Dermabond Protape (Prineo)
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ethicon, Inc.
Burns
The Dermisgraft Epithelialization and Late Scar Healing
Study Synopsis Title; The dermis graft: epithelialization and late scar evaluation A Clinical Prospective multicenter trial Objectives; The objective of this study is to compare a dermal graft with a conventional split thickness…
- Trial name
- NCT05189743
- Testing
- Skin transplantation to heal burn injuries
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
RA - Rheumatoid Arthritis
Pentacam Study of the Cornea in RA Patients
To evaluate the effect of rheumatoid arthritis (RA) activity on the corneal densitometry, corneal curvature (CC), central corneal thickness (CCT), and lens densitometry by Pentacam and compared these parameters with those of…
- Trial name
- NCT05241639
- Testing
- Pentacam
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Healthy Volunteer, Skin
Normal Reference Values in Han Adults of Skin Thickness and Blood Flow by High-frequency Ultrasound
In recent years, high-frequency ultrasound has become a new non-invasive tool for the diagnosis of skin diseases, aesthetic medicine and preoperative and postoperative evaluation due to its higher resolution.
- Trial name
- NOVAS-HFUS (NCT06000163)
- Testing
- high-frequency ultrasound
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Skin Graft Complications
Study to Assess the Safety and Efficacy of DERMASEAL for the Treatment of Split-Thickness Skin Graft Donor Site Wounds
The goal of this study to determine whether the combination biologic/drug DERMASEAL will safely decrease donor wound pain after split-thickness skin graft surgery.
- Trial name
- NCT06134843
- Testing
- DERMASEAL
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hobart W. Harris