Clinical trials: Skin Wrinkling
Wrinkles, Rhytids
Evaluation of the Ulthera® System for Treatment of the Face and Neck
Up to 15 subjects will be enrolled. Enrolled subjects will receive one Ulthera® treatment on the face and neck. Follow-up visits will occur at 45, 90 and 180 days post-treatment.
- Conditions
- Wrinkles, Rhytids, Skin Laxity
- Trial name
- NCT01713907
- Testing
- Ulthera® Treatment
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Skin Aging, Skin Hydration
A Clinical Trial to Evaluate the Effects of Naila's Collagen Marine Plus Food Supplement on Skin Hydration, Elasticity, Fine Lines and Wrinkles, and Hair and Nail Health
This is a single-group, open-label, virtual (decentralized) clinical trial evaluating the effects of Naila's Collagen Marine Plus Food Supplement on skin hydration, elasticity, firmness, fine lines and wrinkles, and hair and nail…
- Conditions
- Skin Aging, Skin Hydration, Skin Elasticity, Fine Lines and Wrinkles
- Trial name
- NCT07746076
- Testing
- Naila's Collagen Marine Plus Food Supplement
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gulf Bird
Photoaging
Effects of Mango Intake on Skin Health and Gut Microbiome Changes in Postmenopausal Women
Mangos are a rich source of nutrients such as carotenoids, vitamin C and fiber, as well as polyphenols and phenolic acids such as mangiferin, ellagic acid, and gallotannins.
- Trial name
- NCT04869852
- Testing
- Food
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Wrinkle
Study to Evaluate the Efficacy of the décoLITE LED Device in Treating the Signs of Skin Aging of the décolletage Area
To assess the efficacy of the décoLITE LED system in reducing the signs of skin aging of the décolletage area one week after a six-week treatment course.
- Trial name
- NCT06542341
- Testing
- decoLITE (TN2037)
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Steven Baker
Skin Aging, Skin Wrinkling
Evaluation of the Safety and Performance Characteristics of Mesofiller Mesotox for the Correction of Wrinkles and Rehydration of the Face.
The investigation is a single-centre, interventional, prospective, non-randomized, open-label, uncontrolled, single-arm, un-blinded investigation for the evaluation of the safety and performance of the product mesofiller® mesotox…
- Trial name
- NCT06477432
- Testing
- mesofiller® mesotox
- Where
- Bulgaria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Wrinkles, Ageing
Assessment of the Impact of a Coenzyme Q10 Supplementation on the Skin
Objective of the study is to determine the influence of dietary supplementation with coenzyme Q10 (CoQ10) on skin conditions. 33 healthy female subjects will be randomly assigned to a placebo group, a low-dose (LD) group…
- Conditions
- Wrinkles, Ageing, Photoprotection
- Trial name
- NCT02604641
- Testing
- Quvital LD group, Quvital HD group
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Wrinkle Appearance, Skin Quality
A Study to Evaluate the Efficacy of Collagen 16 Serum Alone, Against and as an Adjunct to Radiesse® Biostimulation Procedure in Female Trial Participants With Aged Skin
This study aims at assessing the efficacy of improving skin aging signs of a serum containing collagen 16 combined with a biostimulation device in healthy female subjects aged between 30 and 70 years over a period of 13 weeks.
- Trial name
- NCT07446361
- Testing
- Group 1 (Biostimulation + Test product), Group 3 (Test product Alone)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Vichy Laboratoires
Aging, Wrinkle
Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health
Therefore, the present study is designed to contribute to the body of literature by investigating the effect of 12-weeks of lutein supplementation on multiple parameters of skin health and appearance in healthy women.
- Conditions
- Aging, Wrinkle, Skin Elasticity, Healthy
- Trial name
- NCT03769779
- Testing
- FloraGLO Lutein, Safflower Oil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Hair Care, Hair Loss
Olistic_2025 for Hair Loss, Hair Growth, and Skin Improvement
The goal of this randomized, double-blind, placebo-controlled clinical trial is to find out whether daily oral intake of the nutraceutical Olistic Next Women can reduce hair loss, improve hair growth and quality, and improve…
- Conditions
- Hair Care, Hair Loss, Female Pattern Hair Loss
- Trial name
- NCT07300813
- Testing
- Olistic Next Women
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Facial Skin Condition
BeauSaki Bird's Nest Peptide Efficacy
The goal of this clinical trial is to learn whether BeauSaki Edible Bird's Nest Peptide Product can improve facial skin conditions in healthy adult participants.
- Trial name
- NCT07723508
- Testing
- BeauSaki Edible Bird's Nest Peptide Product
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy ＆ Science
Facial Aging, Skin Laxity
Quantified Evaluation of Noninvasive System Delivering Microwave Energy for Unwanted Fat Reduction and Skin Tightening in Asians.
The goal of this observational study is to evaluate the effectiveness and safety of microwave-assisted heating technology in facial fat reduction and skin tightening in Asians. The main questions it aims to answer are: 1.
- Conditions
- Facial Aging, Skin Laxity, Cheek Wrinkles
- Trial name
- NCT06925074
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chang Chang Cheng
Skin Manifestations
The Skin Wrinkle Test: a Simple Clinical Test of Regional Block Success
Wrinkling of the hands and feet with exposure to moist environments is a commonly observed phenomenon. This "stimulated skin wrinkling" (SSW) is the result of direct stimulation of digital nerve sympathetic fibers.
- Trial name
- NCT03873896
- Testing
- Stimulated skin wrinkling test, Digital Nerve Block
- Where
- Canada
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Skin Aging, Wrinkles in Decolletage
PIEZO-101 First-in-Human Safety and Proof-of-Concept Study
The aim of this first-in-human clinical study is to explore the safety, tolerability, pharmacodynamics, and exploratory efficacy of PIEZO-101, an investigational plasmid DNA biostimulator that aims to restore expression of key…
- Conditions
- Skin Aging, Wrinkles in Decolletage, Wrinkles in Left Knee, Left Knee Skin Laxity
- Trial name
- NCT07671027
- Testing
- PIEZO-101, Piezopen, Sterile Saline (0.9% NaCl)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Piezo Therapeutics, Inc.
Skin Aging, Dry Skin
Effects of Probiotics on Skin Health in Healthy Women
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
- Trial name
- NCT07887841
- Testing
- Probiotics
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Probi AB
Skin Texture Irregularities, Facial Skin Wrinkles
Safety & Efficacy Evaluation of a Radiofrequency & Laser/Light System for Improvement of Skin Texture
Evaluate the clinical performance, safety and efficacy, of a Radiofrequency and Laser/Light based device for the treatment of facial wrinkles.
- Trial name
- NCT01597323
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Collagen Degeneration, Wrinkle
The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles
Investigate the topical use of almond oil, almond oil augmented with 0.5% vitamin E, 0.025% tretinoin oil augmented with castor oil on the appearance of facial fine lines and wrinkles, pigmentation, hydration, trans-epidermal…
- Conditions
- Collagen Degeneration, Wrinkle, Pigmentation, Elastic Skin
- Trial name
- NCT06571721
- Testing
- Topical Product: Almond Oil, Topical Product: Almond oil augmented with 0.5% Vitamin E, Topical Product: 0.025% Tretinoin oil augmented with castor oil
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Wrinkle
Confirmatory Study: Assessing the Efficacy and Safety of the AcusMu Microneedle Patch in Treating Periorbital Wrinkles
The core objective of this study is to validate the safe and efficacious application of the AcusMu microneedle patch (FMD WK) to enhance the appearance of periorbital wrinkle
- Trial name
- NCT06158867
- Testing
- FMD WK
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AcusMu Medtech Co., Ltd.
Facail Skin Aging
Facial Exercise and Daily Habit Modification Program for Skin Quality and Wrinkle Severity in Middle-Aged Women
This randomized controlled trial will evaluate the effectiveness of a 12-week program combining facial muscle exercises and daily habit modification for improving skin quality and reducing wrinkle severity in middle-aged women.
- Trial name
- NCT07792460
- Testing
- Facial Exercise and Daily Habit Modification Program
- Where
- Iraq
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Zakho
Aquagenic Wrinkling of Palms, Carrier State
Aquagenic Wrinkling Prediction
The goal of this observational study is to determine whether an aquagenic wrinkling procedure (i.e., soaking hands in a water bath for up to 20 minutes) can be used as a screening tool for cystic fibrosis carrier status.
- Trial name
- NCT06831110
- Testing
- Aquagenic Wrinkling
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Wrinkle
The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties
This study is to analyze the effects of a 5-step skin care regimen on various skin parameters such as pigmentation, and firmness and elasticity of the skin around the eyes.
- Trial name
- NCT05688527
- Testing
- Cleansing Balm, Toning Essence, Facial Serum
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research