Clinical trials: Skin Wrinkling
Facial Skin Wrinkles
Safety And Efficacy Investigation Of The Effects Of ClearLift Q-Switched Nd:Yag 1064nm Laser Module In The Treatment Of Facial Skin Wrinkles
Alma Lasers ClearLift is a fractional non-ablative Q-Switched laser, allowing practitioners to use the benefits of a high intensity QS laser for the treatment of aged skin.
- Trial name
- NCT06349096
- Testing
- Alma Harmony
- Where
- Albania
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
Skin Wrinkling
Autologous Platelet Rich Plasma Combined to Hyaluronic Acid Obtained With Regen-Kit BCT-HA in Aesthetic Medicine
The aim of this prospective study is to assess the efficacy of autologous Platelet Rich Plasma combined with Hyaluronic Acid prepared with RegenKit-BCT HA Cellular Matrix on skin rejuvenation.
- Trial name
- NCT02832583
- Testing
- Regenkit BCT-HA Cellular Matrix
- Volunteers
- 31 people
- Sponsor
- Regen Lab SA
Aging, Wrinkles
Effects of Application LED Therapy and Laser Therapy in Facial Rejuvenation
In today's society, the search for keeping up with the appearance with no visible signs of aging has become common. Therefore, many therapies to try to mitigate these senility markers are present in specialized clinics.
- Trial name
- NCT02513680
- Testing
- Infrared Laser + Amber LED, Amber LED
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Skin Abnormalities
Change in Skin Elasticity With RF and PEMF
This study will measure the difference in skin elasticity in females only before and after treatment with radiofrequency and pulsed electromagnetic field therapy.
- Trial name
- NCT03002194
- Testing
- Cutometer, Photographs
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1
A Proof of Science, Dose-Response Study to Evaluate the Safety, Efficacy of Different Dosages of Test Treatments
A proof of science clinical study with randomized, four-arm, comparative, single-blind, within the arm - Dose-Response Study to evaluate the safety and efficacy of different collagen peptide-containing test treatments in adult…
- Conditions
- Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1, Other Specified Diseases of Hair and Hair Follicles, Brittle Nails
- Trial name
- NCT05613660
- Testing
- Veg Collagen Peptide, Bovine Collagen Peptide, Fish | Marine Collagen Peptide
- Where
- India
- Volunteers
- 264 people
- Sponsor
- NovoBliss Research Pvt Ltd
Skin Aging, Cheek Wrinkles
TCRM for Correction of Cheek Including Fine Lines
The purpose of this clinical study is to evaluate benefits and risks of injecting TCRM in the cheek including fine lines. The goal is to show that treatment with TCRM will result in correcting the cheek area including the fine…
- Trial name
- NCT07145905
- Testing
- TCRM
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Skin Wrinkling
A Study to Validate Cosmetic Outcome Scales Used to Rate Uneven Skin Color and Wrinkling
Skin chronically exposed to the sun may become damaged and then develop wrinkles and/or uneven skin color. The purpose of this research study is to evaluate a newly developed scale (grading tool) that rates wrinkles and uneven…
- Trial name
- NCT00114673
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Graceway Pharmaceuticals, LLC
Intrinsic Aging of Skin, Solar Elastosis
Onabotulinum Toxin Type A and Abobotulinum Toxin Type A Crow's Feet Rhytid Study
The objective of the study is to compare the time to onset of Dysport® versus Botox® in the treatment of lateral orbital rhytids ("crow's feet").
- Trial name
- NCT01529788
- Testing
- Right lateral orbital injection of Botox Cosmetic or Dysport, Left lateral orbital injection of Botox Cosmetic or Dysport
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Maas Clinic
Skin Aging, Skin Wrinkling
Efficacy and Performance Evaluation of mIntense L+AS 25 mg/ml Hyaluronic Acid for the Correction of Moderate to Deep Wrinkles and Folds
The investigation is a single-centre, interventional, prospective, non-randomized, open-label, uncontrolled, single-arm, un-blinded investigation for evaluation of the safety and performance of the product mIntense L+AS in the…
- Trial name
- M-INT-LS (NCT06451822)
- Testing
- mIntense L+AS
- Where
- Bulgaria
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Dermis Density, Trans Epidermal Water Loss (TEWL)
The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters
Placebo controlled double-blind multi-dose comparative study of the effects of coenzyme Q10 and collagen formulation with improved water-solubility in healthy adults.
- Conditions
- Dermis Density, Trans Epidermal Water Loss (TEWL), Skin Hydration, Wrinkles
- Trial name
- Q10-collagen (NCT03811756)
- Testing
- Test syrup containing CoQ10 and collagen
- Where
- Slovenia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- VIST - Faculty of Applied Sciences
Healthy
The Safety and Efficacy of an Oral Superfruits Supplement
This study is conducted to evaluate the safety and effectiveness of an oral superfruits supplement for skin brightening and wrinkle reduction.
- Trial name
- NCT05694182
- Testing
- Other: Oral superfruits supplement
- Where
- Malaysia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- USMARI Research & Innovation Centre
Facial Aging, Wrinkles
Effect of Single Facial Acupuncture on Dermal Structure and Appearance Satisfaction
This study aims to investigate the effects of a single session of facial rejuvenation acupuncture on skin structure and personal satisfaction with facial appearance.
- Conditions
- Facial Aging, Wrinkles, Skin Aging
- Trial name
- FRA (NCT07664280)
- Testing
- Facial Rejuvenation Acupuncture (FRA)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Chronic Effect of Ultraviolet Radiation on Photoaged Skin, Dermatologic Disorders
Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging
The purpose of this study is to determine whether a one-time injection of allogeneic mesenchymal bone marrow cells is safe and beneficial in the treatment of photodamage on the face.
- Trial name
- NCT01771679
- Testing
- Allogeneic Mesenchymal Bone Marrow Cells
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Stemedica Cell Technologies, Inc.
Lipoatrophy, Aging
Safety Study of Antria Cell Preparation Process to Enhance Facial Fat Grafting With Adipose Derived Stem Cells
The primary purpose of this study is to demonstrate the safety of injecting the Stromal Vascular Fraction (SVF) [containing Adipose Derived Stem Cells (ADSCs)] enriched fat grafts into regions of the face that require…
- Conditions
- Lipoatrophy, Aging, Wrinkles
- Trial name
- NCT01828723
- Testing
- SVF
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Antria
Aging, Wrinkle
Efficacy of Four Topical Products to Improve Skin Longevity
The objective of this study is to determine the efficacy of four topical products to improve facial skin longevity over an eight-week use period utilizing analysis of images and self-perception questionnaires.
- Trial name
- Before/After (NCT07118943)
- Testing
- Face care product
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Skin Laxity
Assess Efficacy of a Nanodiamond Periprocedural Skin Care Regimen for Ablative Resurfacing
The primary objective of this study is to evaluate the efficacy and tolerability of Pavise Extracellular Matrix Restore (ECMR), compared with standard acute post-operative care, when used as the primary occlusive treatment…
- Trial name
- NCT07462533
- Testing
- Pavise Serum, Co2/Er:YAG
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Intrinsic Aging of Skin
Comparative Study of Reconstituted JUVÉDERM® Ultra vs COSMODERM® 1 for Lip and Cheek Lines, Folds or Wrinkles
This study is being done to evaluate the differences in the performance of two well known injectable dermal fillers commonly used for the cosmetic treatment of age lines above the lips and on the cheeks when compared to each…
- Trial name
- JUVE_COSMO_1 (NCT01212809)
- Testing
- Juvéderm Ultra, Cosmoderm 1
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Steven Fagien
Sin Health, Skin Hydration
Clinical Study to Evaluate the Impact of aKwa Skincare System on Skin Health
The purpose of the study was to evaluate the effectiveness of the äKwä 6-step skincare system by measuring skin moisture level, fine lines and wrinkles, porphyrin count, red spots, and red vasculature counts over a 30-day period.
- Conditions
- Sin Health, Skin Hydration, Skin Wrinkles, Skin Porphyrins
- Trial name
- NCT05476406
- Testing
- äKwä skincare system products, competitor products (control)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- 4Life Research, LLC
Skin Aging
Poly-L-lactic Acid for Skin Quality
Anecdotal evidence suggests that patients' skin quality may improve as a result of poly-L-lactic acid injection. While this is not the primary goal of such treatments it is often seen and described as so called "Sculptra glow".
- Trial name
- NCT02003833
- Testing
- Poly-L-lactic acid
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sadick Research Group
Lax Skin, Improve Facial Wrinkles
In Vivo Study to Evaluate Tissue Remodeling Via Fibroblast Stimulation Following a Single SofWave Treatment
Open-label, non-randomized single-arm prospective, single-center, self-controlled clinical study.
- Trial name
- NCT07685821
- Testing
- Sofwave
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD