Clinical trials: Sleep
Sleep Disorders, Obstructive Sleep Apnea
Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression
The primary objective of the study is to evaluate whether armodafinil at a target dosage of 200 mg/day is more effective than placebo treatment in improving excessive sleepiness in patients with obstructive sleep apnea/hypopnea…
- Conditions
- Sleep Disorders, Obstructive Sleep Apnea, Major Depressive Disorder, Dysthymic Disorder
- Trial name
- NCT00518986
- Testing
- armodafinil
- Where
- 62 sites in United States
- Volunteers
- 249 people
- Sponsor
- Cephalon
Insomnia, Ulcerative Colitis
Piloting an Insomnia Treatment in Patients With Ulcerative Colitis
The goal of this clinical trial is to learn if telehealth-based Cognitive Behavioral Therapy for Insomnia (CBT-I) adapted for Ulcerative Colitis (UC) works to treat insomnia in adults with UC.
- Trial name
- RISE-UC (NCT07428629)
- Testing
- CBT-I UC
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Chronic Low Back Pain, Chronic Neck Pain
Cognitive Behavioural Therapy for Insomnia in Chronic Spinal Pain
Chronic spinal pain (CSP) includes chronic low back and neck pain. CSP is a highly prevalent and severely debilitating disorder characterized by tremendous personal and socioeconomic impact, long-term sick leave, low quality of…
- Conditions
- Chronic Low Back Pain, Chronic Neck Pain, Insomnia Chronic
- Trial name
- NCT03482856
- Testing
- MNA plus CBT-I, MNA alone
- Where
- 2 sites in Belgium
- Volunteers
- 123 people
- Sponsor
- University Ghent
Insomnia
National Adaptive Trial for PTSD Related Insomnia
Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD.
- Trial name
- NAP (NCT03668041)
- Testing
- Trazodone, Eszopiclone
- Where
- 35 sites in United States
- Volunteers
- 673 people
- Sponsor
- VA Office of Research and Development
Sleep, Insomnia
Repurposing Dexmedetomidine as an Orally Administered Sleep Therapeutic
The broad objective of this investigation is to assess the safety and efficacy of oral therapy with dexmedetomidine for the induction and maintenance of restful sleep.
- Trial name
- NCT02818569
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obstructive Sleep Apnea, Diabetes Mellitus, Type 2
Correlation Between Nocturnal Oxygen Desaturation and Glycemic Control in Diabetic Patients With Obstructive Sleep Apnea
Nocturnal reduction in blood oxygen is expected independently associated with the development of worsened glycemic control in individuals with type 2 diabetes mellitus.
- Trial name
- NCT04711083
- Testing
- overnight pulse oximetry
- Where
- Egypt
- Volunteers
- 107 people
- Sponsor
- Ain Shams University
Cancer
The Effect of Self-Acupressure Application on Pain, Fatigue and Sleep Quality in Cancer Patients Receiving Chemotherapy
The aim of this study is to examine the effect of Self-Acupressure application on pain, fatigue and sleep quality in cancer patients receiving chemotherapy.
- Trial name
- NCT04930341
- Testing
- Self-Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Geriatric
Effects of Thoracic Mobility Exercises in Geriatric Individuals
Aging leads to a gradual decline in muscle function and structural changes in the musculoskeletal system, which can affect balance and increase the risk of falls.
- Trial name
- Geriatric (NCT06876922)
- Testing
- Thoracic mobility exercises Group, the Conventional physiotherapy exercises Group
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Stroke
Factors Affecting Physical Activity in Stroke
The aim of our study is to examine the factors affecting the physical activity of individuals with stroke and to draw attention to the importance of these factors in interventions to improve the physical activity level of…
- Trial name
- NCT06049069
- Testing
- physical activity in stroke
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Kırıkkale University
Sleep
Sleep and Food-based Decision Making
This study administers two prescribed sleep levels, each lasting one week, that participants will complete in their at-home environment.
- Trial name
- NCT05728983
- Testing
- Sleep levels
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Sleep Apnea, Obstructive, Obstructive Sleep Apnea Syndrome
Usefulness of a Telemedicine System for OSA Patients Follow-up With High Cardiovascular Risk
The aim of this study is to determine the usefulness of a telemedicine system for the follow-up of OSA patients with a high cardiovascular risk.
- Trial name
- TELESAS (NCT01226641)
- Testing
- Telemedicine, Standard care
- Where
- 14 sites in France
- Volunteers
- 107 people
- Sponsor
- Initiative Pour la Sante
Cerebral Stroke, Stroke, Acute
Safety and Effectiveness of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke
This study will determine if NXY-059 will improve recovery from an acute stroke. The study is designed to look at both overall recovery and recovery of motor function, for example muscle strengthen and coordination.
- Conditions
- Cerebral Stroke, Stroke, Acute, Cerebrovascular Stroke, Ischemic Attack, Transient
- Trial name
- NCT00061022
- Testing
- NXY-059
- Where
- 256 sites in United States, Argentina and 28 more
- Volunteers
- 3,200 people
- Sponsor
- AstraZeneca
Obstructive Sleep Apnea
Home Diagnosis and Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) is a common and underrecognised condition. The diagnosis of OSA is typically made after an in-lab polysomnography (PSG) which requires an overnight stay in a sleep laboratory.
- Trial name
- NCT00139022
- Testing
- Continuous Positive Airway Pressure
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Saskatchewan
Primary Insomnia
Sleep Inducing And Maintaining Efficacy Of Circadin In Elderly Insomniacs
The aim of this placebo controlled study is to investigate the effect of 2 mg melatonin Slow Release (Circadin®) on the sleep/wake cycle in elderly insomniac out-subjects, aged 55 years or more.
- Trial name
- Neu I (NCT00816673)
- Testing
- Circadin
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Obstructive Sleep Apnea of Adult
An Extension Study to Assess the Long-term Safety of the Genio® System
The objective of this study is to assess the long-term safety of the Genio® system in adult OSA patients with and without complete concentric collapse of the soft palate who have successfully been implanted with the Genio IS in a…
- Trial name
- OLE (NCT05939141)
- Testing
- Genio System
- Where
- 7 sites in Australia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Nyxoah S.A.
Insomnia, Depression
Acupuncture for Residual Insomnia Associated With Major Depressive Disorder
The purpose of this study is to evaluate the clinical effectiveness of acupuncture treatment on residual insomnia in major depressive patients.
- Trial name
- NCT00838994
- Testing
- Acupuncture
- Where
- Hong Kong
- Volunteers
- 78 people
- Sponsor
- The University of Hong Kong
Obstructive Sleep Apnea
Effectiveness of Compression Stocking on Overnight Fluid Shift in Obstructive Sleep Apnoea Patients
Overnight rostral fluid shift is one of the contributing factors for worsening obstructive sleep apnoea (OSA). Fluid shift has been recognized to play a role in the pathophysiology of sleep apnoea.
- Trial name
- NCT04917094
- Testing
- Compression stocking
- Where
- Singapore
- Volunteers
- 29 people
- Sponsor
- Khoo Teck Puat Hospital
Sleep Apnea, Obstructive
The Influence of the Sleep Apnea on the Neurological and Functional Recovery
The sleep respiratory troubles (central apnea or CHEYNES-Stokes dyspnea) are frequent after stroke. The association of the sleep respiratory troubles with a reserved functional prognosis is debated.
- Trial name
- SAS-AVC (NCT01321229)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery, Anxiety
The Effect of Diaphragmatic Breathing Exercise on Symptom Severity, Sleep Quality and Anxiety in CABG Patients.
Coronary artery bypass surgery (CABC) is a commonly performed surgical procedure for the treatment of blockages in the heart vessels. This surgical intervention aims to improve the blood circulation of the patients' heart muscle.
- Conditions
- Coronary Artery, Anxiety, Symptom, Sleep
- Trial name
- NCT06356896
- Testing
- diaphragmatic breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- KTO Karatay University
Stress, Psychological, Stress, Emotional
Biology, Identity & Opportunity Study
This study will implement an intervention designed to promote ethnic and racial identity development. It is hypothesized that the intervention will have positive effects on ethnic-racial identity development, stress biology…
- Conditions
- Stress, Psychological, Stress, Emotional, Stress, Physiological
- Trial name
- BIO (NCT03412162)
- Testing
- Ethnic and Racial Identity Promotion, Academic Skills Promotion
- Where
- 3 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Northwestern University