Clinical trials: Sleep Disturbance in Advanced Cancer
Carcinoma, Non-Small-Cell Lung, Sleep Wake Disorders
Low-Frequency rTMS for In-Hospital Sleep Disturbance in Advanced NSCLC
This randomized, double-blind, sham-controlled trial will evaluate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) can improve in-hospital sleep quality in adults with advanced non-small cell lung cancer…
- Trial name
- NCT07796438
- Testing
- Active Low-Frequency Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 160 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Advanced Malignant Solid Neoplasm, Delirium
Suvorexant for Insomnia to Prevent Delirium in Hospitalized Cancer Patients
This phase IV trial compares suvorexant with standard of care to standard of care alone for improving difficulty sleeping (insomnia) and reducing confusion (delirium) in hospitalized cancer patients.
- Conditions
- Advanced Malignant Solid Neoplasm, Delirium, Hematopoietic and Lymphatic System Neoplasm, Insomnia
- Trial name
- NCT06834386
- Testing
- Best Practice, Electronic Health Record Review, Interview
- Where
- United States
- Sponsor
- Mayo Clinic
Sleep Disturbance in Advanced Cancer
Sleep Well At Night
Research has shown that the incidence of sleep disturbances in people with cancer is much higher than in the general population. Sleep problems can lead to worse symptoms, quality of life, and potentially impact outcomes.
- Trial name
- SWAN (NCT07068971)
- Testing
- Online cognitive behavioural therapy for insomnia, bright light therapy, activity
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Our Lady's Hospice and Care Services
Rectal Cancer, Low Anterior Resection Syndrome
Impact of Quality of Life in the Patients With Sleep Disturbance From Low Anterior Resection Syndrome in Advanced Rectal Cancer Patients
The preservation surgery of the anal sphincter has become a standard procedure for the treatment of rectal cancer and is now possible even when the tumor is close to the anus, thanks to the advancement of surgical techniques.
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, Insomnia
- Trial name
- NCT06271629
- Testing
- Insomnia severity index
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Sleep Disorders, Neoplasms
Sleep Quality in Patients With Advanced Cancer
The primary focus of this clinical study is the objective and subjective measurements of sleep quality in patients with advanced cancer using opioids.
- Trial name
- NCT02585609
- Where
- Norway
- Volunteers
- 41 people
- Sponsor
- Norwegian University of Science and Technology
Sleep, Fatigue
Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer
To learn if Cognitive Behavior Therapy (called CBT), combined with either Bright Light Therapy (called BLT), methylphenidate, and/or melatonin, can help improve sleep and other related symptoms such as fatigue, anxiety, and…
- Conditions
- Sleep, Fatigue, Anxiety, Cancer
- Trial name
- NCT05474846
- Testing
- Melatonin, Methylphenidate
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer, Circadian Rhythm Disorders
Identifying Circadian Rest-Activity Rhythm Disorders in Patients With Advanced Cancer
Circadian rest-Activity Rhythm disorders (CARDs) are common in patients with cancer, particularly in advanced disease. CARDs are associated with increased symptoms, poorer quality of life, poorer response to anticancer treatments…
- Conditions
- Cancer, Circadian Rhythm Disorders, Sleep Disturbance, Activity, Motor
- Trial name
- NCT06023654
- Where
- 2 sites in Ireland
- Volunteers
- 100 people
- Sponsor
- University of Dublin, Trinity College
Oncology, Insomnia
Efficacy of Hypno-ear-acupuncture on Insomnia in Advanced Cancer Patients
This randomized controlled trial aims to test if a combination of medical hypnosis and ear acupuncture improves sleep quality in patients with advanced cancer during a hospital stay in a palliative care unit.
- Conditions
- Oncology, Insomnia, Symptoms and Signs
- Trial name
- NCT06532188
- Testing
- Hypno-ear-acupuncture
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Graz
Oral Cancer, Pharynx Cancer
Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer.
Evaluation of the Tolerance and Benefits of Mandibular Advanced Device (MAD) for Snoring and Sleep Apnea in Patients with Oropharyngeal Cancer (OPC): Mixed Design Study.
- Conditions
- Oral Cancer, Pharynx Cancer, Sleep Apnea, Snoring
- Trial name
- Ronco-Onco (NCT05719779)
- Testing
- Ronco-Onco and MAD
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pain, Fatigue
A Brief Patient-Controlled Intervention for a Symptom Cluster in Advanced Cancer
The purpose of the research is to test the efficacy of a patient-controlled cognitive-behavioral intervention for pain, fatigue, and sleep disturbance during cancer treatment, and to evaluate moderators and mediators of…
- Conditions
- Pain, Fatigue, Sleep Disturbance, Cancer
- Trial name
- NCT01954420
- Testing
- Cognitive-Behavioral Intervention, Attention Control
- Where
- 4 sites in United States
- Volunteers
- 188 people
- Sponsor
- University of Wisconsin, Madison
Sleep, Insomnia
Pharmacological Treatment of Insomnia in Palliative Care
Sleep disturbance is frequent in patients with advanced cancer and decreases the tolerability of other symptoms and impairs quality of life.
- Trial name
- NCT02807922
- Testing
- Zopiclone
- Where
- 5 sites in Norway
- Volunteers
- 43 people
- Sponsor
- St. Olavs Hospital
Advanced Cancer, Anorexia
Effects of Mirtazapine on Appetite in Advanced Cancer Patients
Primary objective: This is a preliminary study to determine if Mirtazapine in comparison to placebo will improve appetite in advanced cancer patients with anorexia and weight loss.
- Conditions
- Advanced Cancer, Anorexia, Weight Loss, Insomnia
- Trial name
- NCT00488072
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- M.D. Anderson Cancer Center
Advanced Cancers
The Use of Light Therapy for Managing Sleep Disturbances in Patients With Advanced Cancer
The goal of this research study is to learn if a type of light therapy can be used to help patients with advanced cancer who are having difficulty sleeping to sleep better.
- Trial name
- NCT01193530
- Testing
- Bright Light Therapy, Dim Red Light Therapy, Questionnaires
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- M.D. Anderson Cancer Center