Clinical trials: Sleep Obstructive Apnea
Atrial Fibrillation, Continuous Positive Airway Pressure
Clinical Study on the Effect of CPAP on AF Recurrence After Catheter Ablation in Patients with AF and OSA
Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice, significantly increasing the risks of death, stroke, heart failure, cognitive impairment, and dementia, thus severely impacting patients'…
- Conditions
- Atrial Fibrillation, Continuous Positive Airway Pressure, Obstructive Sleep Apnea, Recurrence
- Trial name
- NCT06542263
- Testing
- CPAP
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Obstructive Sleep Apnea
Effect of CPAP Treatment in Cognition in Adults With DS and OSA
Adults with Down syndrome (DS) have a high prevalence of obstructive sleep apnea (OSA), which may worsen cognitive performance. In general population, continuous positive airway pressure (CPAP), the gold Standard treatment for…
- Trial name
- NCT04198493
- Testing
- CPAP, CONSERVATIVE TREATMENT for OSA
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Heart Failure, Arteriosclerosis of Coronary Artery Bypass Graft or Other Coronary Reperfusion
PAC-IC-SAOS Obstructive Sleep Apnea Syndrome and Ventricular Function
The aim of this clinical trial is to evaluate the effect of obstructive sleep apnea syndrome (OSAS) treatment in heart failure patients following coronary artery bypass graft (CABG) surgery or other coronary reperfusion.
- Conditions
- Heart Failure, Arteriosclerosis of Coronary Artery Bypass Graft or Other Coronary Reperfusion, Sleep Apnea, Obstructive
- Trial name
- PAC-IC-SAOS (NCT01900379)
- Testing
- CPAP treatment
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea, Telemedicine
Global Self-management Telematic Support for Patients With Obstructive Sleep Apnea.
This clinical trial compares the usual follow-up to a program of telematic control and self-management in a group of patients with severe obstructive sleep apnea-hypopnea syndrome (OSAHS), few symptoms and treated with continuous…
- Conditions
- Obstructive Sleep Apnea, Telemedicine, Compliance, Patient
- Trial name
- TELESAS (NCT03792880)
- Testing
- Telematic control and self-management program, Habitual follow-up in Healthcare System
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Virgen del Puerto Hospital
Obstructive Sleep Apnea
Targeted Hypoglossal Neurostimulation Study #3
The purpose of this study is to evaluate the benefits and risks of hypoglossal nerve stimulation with the ImThera Medical aura6000 System as a potential therapeutic option for individuals with moderate to severe OSA that have…
- Trial name
- THN3 (NCT02263859)
- Testing
- aura6000 System
- Where
- 20 sites in United States, Belgium and 4 more
- Volunteers
- 138 people
- Sponsor
- ImThera Medical, Inc.
Obesity, Obesity, Maternal
Obesity and OSA in Pregnancy
The purposes of this project are 1) to compare the impact of maternal obesity versus excessive gestational weight gain on obstructive sleep apnea (OSA) in obese and non-obese women; 2) to investigate the mechanism(s) by which…
- Conditions
- Obesity, Obesity, Maternal, Obstructive Sleep Apnea, Blood Pressure
- Trial name
- NCT05654259
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- University of Texas Southwestern Medical Center
Obstructive Sleep Apnea (OSA)
Point of Care Ultrasound in Pregnant Women (PoCUS-OB)
Pregnant women with gestational age more than 20 weeks are at risk of developing Obstructive Sleep Apnea (OSA). OSA is a common underdiagnosed comorbid condition in pregnant women associated with adverse maternal and fetal…
- Trial name
- NCT06776237
- Testing
- PoCUS
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea, Metabolic Dysfunction-Associated Steatotic Liver Disease
Association Between Metabolic Associated Fatty Liver Disease and Obstructive Sleep Apnea
Association between Metabolic Associated Fatty Liver Disease and Obstructive Sleep Apnea
- Trial name
- OSA/MAFLD (NCT07716995)
- Volunteers
- 127 people
- Sponsor
- Assiut University
Otolaryngological Disease, Obstructive Sleep Apnea
Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils
The purpose of this study is to compare the effectiveness of a novel personalized surgical approach to the standard AT in children with small tonsils (ST).
- Trial name
- TOPS-ST (NCT06258837)
- Testing
- DISE-Directed Surgery, Adenotonsillectomy
- Where
- 2 sites in United States
- Volunteers
- 175 people
- Sponsor
- Oregon Health and Science University
Obstructive Sleep Apnea
Validation of a New Automatic Bi-level Algorithm in the Treatment of Sleep-disordered Breathing
Between 2%-4% of adult population suffers from obstructive sleep apnea (OSAS)(1), which is characterized by obstructive snoring, repetitive apnea and hypopnea in sleep, repetitive cyclic oxygen saturation, as a result from sleep…
- Trial name
- NCT00910195
- Testing
- CPAP treatment with subsequent Bi-Level-APAP treatment, Bi-Level-APAP treatment with subsequent CPAP treatment
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Ehlers-Danlos Syndrome, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
- Trial name
- OSA in EDS (NCT02435745)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstructive Sleep Apnea, Obesity
A Study of Surgical Weight Loss to Treat Obstructive Sleep Apnea
Obesity is an increasing problem worldwide. Over 20% of people in western societies are obese (BMI >30kg/m2) and 1-2 % are morbidly obese (BMI >40 kg/m2).
- Trial name
- NCT01080404
- Testing
- Bariatric surgery, Continuous positive airway pressure
- Where
- 9 sites in Finland
- Volunteers
- 197 people
- Sponsor
- Kuopio University Hospital
Obesity-hypoventilation Syndrome, Resting Energy Expenditure
Resting Energy Expenditure in Patients With OHS Treated With Long-term NIV
This study aims to compare, in subjects with obesity-hypoventilation syndrome (OHS) treated by long-term non-invasive ventilation (NIV), resting energy expenditure (REE) in spontaneous breathing and under NIV.
- Conditions
- Obesity-hypoventilation Syndrome, Resting Energy Expenditure, Long-term Non-invasive Ventilation
- Trial name
- NCT04474587
- Testing
- Indirect calorimetry
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Ischemic Stroke, Acute Coronary Syndrome
Comparative Study of Arterial Properties After an Ischaemic Stroke or an Acute Coronary Syndrome
A pilot, prospective, comparative study. To include both male and female patients who have presented an ischaemic stroke (full stroke or TIA) or an ACS, 5 to 30 days prior to inclusion.
- Conditions
- Ischemic Stroke, Acute Coronary Syndrome, Obstructive Sleep Apnea Syndrome
- Trial name
- AVC/SCA (NCT00926874)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Goiter
Effects of Thyroidectomy on Obstructive Sleep Apnea in Patients Suffering From Goiters
Literature regarding effects of goiter on the occurrence of obstructive sleep apnea (OSA) remains scarce. Reports have described cases of OSA in patients suffering from goiters, resolved after thyroidectomy.
- Trial name
- NCT05391945
- Testing
- polysomnography
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Obstructive Sleep Apnea
The Role of the Device Operating Under the Continuous Positive Airway Pressure in the Recovery Process of Cochlea
Hypothesis: Patients with obstructive sleep apnea syndrome (OSAS) have cochlear receptor cells damage because of prolonged, recurrent hypoxia.
- Trial name
- NCT05362890
- Testing
- DEVICE OPERATING UNDER THE CONTINOUS POSITIVE AIRWAY PRESSURE
- Where
- Croatia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mirjana Grebenar Cerkez
Obstructive Sleep Apnea
Baveno Classification Versus Polysomnography in Obstructive Sleep Apnea
Obstructive sleep apnea is a common disorder associated with significant cardiovascular and metabolic risks. Polysomnography is considered the gold standard for diagnosis and severity assessment; however, it may not fully reflect…
- Trial name
- NCT07594288
- Volunteers
- 395 people
- Sponsor
- Hisar Intercontinental Hospital
Pulmonary Disease, Chronic Obstructive
Efficacy of Self-titration of Ventilation in Overlap Syndrome (chronic Obstructive Pulmonar Disease + Sleep Apnea Syndrome ) with Dynamic Hyperinflation. EDIN-IDIN.
The combination of COPD and obstructive sleep apnea (OSA) can lead to undesirable interactions with the treatment approach. The investigators know that continuous positive airway pressure (CPAP) can increase dynamic…
- Trial name
- EDIN-IDIN (NCT06713486)
- Testing
- Fixed pressure obtained in the polysomnography for 28 days, Dynamic pressure in Dreamstation AVAPS-AAM PhilipsRespironic® mode
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Obstructive Sleep Apnea
Obstructive Sleep Apnea in World Trade Center Responders
The goal of the study is to examine the possible underlying causes of sleep apnea (a disorder in which there are problems with breathing during sleep) in World Trade Center Responders.
- Trial name
- NCT01753999
- Testing
- Standard CPAP, CPAP - Flex
- Where
- 3 sites in United States
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Obstructive Sleep Apnea
Reiterative Development and Evaluation Study of OSA Therapy System
The purpose of this study is to evaluate new iterations/generations of the ApniCure sleep therapy device.
- Trial name
- NCT01634074
- Where
- 7 sites in United States
- Volunteers
- 150 people
- Sponsor
- ApniCure, Inc.
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