Clinical trials: Sleep Restriction
Insomnia
Treatments for Insomnia: Mediators, Moderators and Quality of Life
The purpose of this study is to evaluate the relative efficacy and effectiveness of specific components of cognitive behavioral therapies for insomnia: sleep restriction (SR) and cognitive therapy (CT) in comparison to combined…
- Trial name
- NCT02117388
- Testing
- Sleep Restriction, Cognitive Behavioral Therapy, Combined Therapy
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
Sleep, Sleep Deprivation
Sleep Duration Required to Restore Performance During Chronic Sleep Restriction
The purpose of this study is to test the hypothesis that sleep and performance depend on length of time awake, length of time asleep, the amount of sleep over several sleep episodes, and circadian phase.
- Conditions
- Sleep, Sleep Deprivation, Insufficient Sleep Syndrome
- Trial name
- NCT01581125
- Testing
- Sleep:wake 1, Sleep:wake 2
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Deprivation, Sleep Restriction
Acoustic Stimulation During Restricted Sleep After Sleep Deprivation
The purpose of this study is to determine if brief sounds or tones presented within a restricted period of recovery sleep after a period of sleep deprivation will enhance restorative properties and improve performance during a…
- Conditions
- Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance
- Trial name
- NCT05309473
- Testing
- Philips SmartSleep Acoustic Stimulation Device
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Sleep Restriction
Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women
The purpose of this study is to 1) determine how hypothalamic-pituitary-adrenal axis (HPA axis) activation occurs with sleep restriction and 2) evaluate how hypothalamic-pituitary-gonadal axis (HPG axis) deactivation occurs with…
- Trial name
- NCT04037605
- Testing
- Ketoconazole Pill (also known as nizoral), Ganirelix, Dexamethasone Pill
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Sleep
Effect of Sleep Restriction on Metabolic Disturbances Caused by Overfeeding
The purpose of this study is to determine if sleep restriction provokes an increase in risk factors for metabolic diseases, such as elevation of ectopic fat and decreased sensitivity to insulin.
- Trial name
- NCT02075723
- Testing
- Overfeeding (130 % of energy requirements ), Sleep restriction (4 hours per night)
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Caloric Restriction, Exercise
Trial of Testosterone Undecanoate for Optimizing Performance During Military Operations
The objective of this study is to determine the effects of a single dose of testosterone undecanoate during and in recovery from simulated operational stress.
- Conditions
- Caloric Restriction, Exercise, Sleep
- Trial name
- OPS II (NCT04120363)
- Testing
- Testosterone Undecanoate, Sesame Oil
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Sleep Deprivation
Study on the Mechanism of Central Obesity Induced by Sleep Restriction and the Therapeutic Effect of n-3 Polyunsaturated Fatty Acid: a Randomized, Double-blind, Placebo-controlled Trial (COSPA Study)
This randomized, double-blind, placebo-controlled trial aims to investigate whether n-3 polyunsaturated fatty acid (PUFA) supplementation attenuates abdominal visceral fat accumulation induced by experimental sleep restriction.
- Trial name
- NCT07897097
- Testing
- n-3 PUFA Supplementation, Experimental Sleep Restriction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Sleep, Appetitive Behavior
Time-restricted Eating, Appetite and Sleep
The goal of this clinical trial is to learn about the effect of time-restricted eating (TRE) to 10 hours per day on the regulation of appetite, the desire to eat, and the quality and duration of nocturnal sleep in adults with…
- Trial name
- SLEEPFAST (NCT06485037)
- Testing
- Time-restricted eating
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Chile
Obesity, Diet Modification
Metabolic Impact of Time Restricted Feeding
The investigators are interested in how time-restricted feeding will impact weight, sleep duration and efficacy, and activity levels in obese adults.
- Trial name
- NCT03129581
- Testing
- Dietary Counseling
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sleep Restriction
Effects of Nap Restriction on Preschoolers' Empathy, Prosocial Behaviors and Executive Function
Cross-sectional evidences suggest a relationship between early childhood sleep and cognitive as well as socio-emotional functions. However, the casual relation has not been fully revealed.
- Trial name
- NCT06025669
- Testing
- Nap restriction
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Sleep Deprivation
Chronic Sleep Restriction and Driving
Young subjects and patients with nocturnal respiratory disorders are frequently involved in sleep-related accidents. This study assess the impact of chronic sleep restriction (4 hr of sleep during 5 days) or total sleep…
- Trial name
- PRIVASOM (NCT00560456)
- Testing
- Chronic sleep restriction and driving simulator
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Obesity, Sleep Restriction
Effects of Time of Sleep Restriction in Obesity
The purpose of this study is to determine the effect of different time of sleep restriction on control of food intake and metabolism of obese and normal subjects.
- Conditions
- Obesity, Sleep Restriction, Appetite Regulation, Eating
- Trial name
- NCT01259895
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Chronic Low-back Pain, Insomnia
Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study
Our goal is to observational study is to determine feasibility of partial sleep restriction in individuals with CLBP+I and correlation findings with features of central sensitization.
- Conditions
- Chronic Low-back Pain, Insomnia, Sleep
- Trial name
- NCT07008924
- Testing
- No intervention is provided. We monitor natural recovery to full sleep.
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Sleep Deprivation
Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period
Short sleep duration confers high cardiovascular and metabolic risk, but lifestyle factors and molecular mechanisms that contribute to increased blood pressure and poor glucose control during short sleep are not completely…
- Trial name
- CRISP (NCT06070194)
- Testing
- Time restricted eating (TRE)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Sleep Deprivation
Sleep Deprivation and Energy Balance
Chronic sleep deprivation may constitute an important and potentially correctable behavioral factor in the alarming increase in obesity.
- Trial name
- NCT01334788
- Testing
- sleep deprivation, Normal sleep
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obstructive Sleep Apnea
Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea
This study evaluates the intervention of the 1) sodium-restricted diet, or 2) diuretic, or 3) placebo pill in the treatment of obstructive sleep apnea in adults.
- Trial name
- DESALT (NCT01945801)
- Testing
- Lasilactone, Sodium-Restricted Diet
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Healthy
Repeating Patterns of Sleep Restriction and Recovery
Goal of this study is to test the hypothesis that repeated exposure to cycles of insufficient sleep increases susceptibility to a variety of disease states by progressively compromising the integrity of stress response systems.
- Trial name
- NCT01523691
- Testing
- Repeated sleep restriction and recovery, Control sleep
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Sleep Deprivation, Obesity
Sleep and Metabolism
The goal of this study is to uncover sleep and circadian mechanisms contributing to adverse metabolic health. The protocol is a 21 day (7 outpatient days, 14 inpatient days) mechanistic randomized-crossover study designed to…
- Conditions
- Sleep Deprivation, Obesity, Glucose Intolerance, Weight Gain
- Trial name
- SAM (NCT05775627)
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sleep Restriction
Hormonal Mechanisms of Sleep Restriction - Axis Study
The purpose of this study is to 1) determine how hypothalamic-pituitary-adrenal axis (HPA axis) activation occurs with sleep restriction 2) evaluate how hypothalamic-pituitary-gonadal axis (HPG axis) deactivation occurs with…
- Trial name
- NCT03142893
- Testing
- Ketoconazole Pill, Ganirelix, Dexamethasone
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Peter y. Liu
Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease
Countermeasures to Circadian Misalignment
Insufficient sleep and circadian misalignment are independent risk factors for the development of obesity and diabetes, yet few strategies exist to counter metabolic impairments when these behaviors are unavoidable.
- Conditions
- Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease, Insulin Sensitivity
- Trial name
- C2CM (NCT04966351)
- Testing
- Time-restricted feeding, Circadian Misalignment
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Colorado State University