Clinical trials: Sleep Restriction, open to volunteers
Cardiometabolic Syndrome, Type 2 Diabetes
Circadian Intervention to Improve Cardiometabolic Health
The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD).
- Conditions
- Cardiometabolic Syndrome, Type 2 Diabetes, Sleep, Time Restricted Feeding
- Trial name
- TOCS (NCT05943626)
- Testing
- Circadian Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Utah
Chronic Insomnia
Effects of Relaxation Training and Stimulus Control in Chronic Insomnia Patients
The study aims to validate the effect of relaxation training and stimulus control on reducing hyperarousal states and improving maladaptive sleep behaviors.
- Trial name
- NCT06658171
- Testing
- Relaxation training and stimulus control, Sleep hygiene education
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xuanwu Hospital, Beijing
Insomnia
Cognitive-behavioral Therapy for Insomnia in School-aged Children
This randomized controlled trial will test the efficacy of CBT-I intervention for school-aged children (7-11 years old) with insomnia. The trial will focus on the role of sleep restriction therapy in treatment.
- Trial name
- NCT07048340
- Testing
- Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia without SRT
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel Aviv University
Sleep Quality, Compliance
Changes in 24-hour Activity Cycle Behaviors During a Time-Restricted Eating Intervention in College-Aged Women
Time-restricted Eating (TRE) is a dietary approach that limits food intake to 4 - 12-hour windows without intentionally altering diet quality.
- Conditions
- Sleep Quality, Compliance, Physical Activity, Sedentary Behaviors
- Trial name
- DAWG-TREAT (NCT07520786)
- Testing
- Time Restricted Eating, Control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Sleep, Insomnia
The Effect of Sleep Loss on Emotion Regulation
The study is designed to investigate the impact of three nights of sleep restricted to 4 hours per night, on the processing and regulation of emotional information compared to Insomnia Disorder and control.
- Conditions
- Sleep, Insomnia, Sleep Deprivation
- Trial name
- NCT05393830
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Hypertension
Sleep Restriction and Parental History of Hypertension
The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal…
- Trial name
- NCT06482814
- Testing
- Partial sleep deprivation (sleep restriction), Normal sleep
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Autism Spectrum Disorder (ASD), Autism
Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism
The purpose of this open label trial is to examine the acceptability, tolerability, and feasibility and preliminary effectiveness of sleep restriction therapy for sleep problems in children with autism spectrum disorder (ASD).
- Trial name
- NCT06627205
- Testing
- Sleep Restriction Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Sleep, Blood Pressure
Impact of Sleep Restriction on Blood Pressure Reactivity
The purpose of the research study is to examine the effects of shortened sleep on blood pressure.
- Trial name
- NCT07489417
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Sleep Deprivation, Nutritional Intervention
Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.
Sleep deprivation is a major problem in military populations. Some major consequences of sleep loss are inability to concentrate, poor work efficiency, and increase in errors during daily tasks.
- Trial name
- NCT06075914
- Testing
- Ketogenic Intervention, Mediterranean Intervention, Ketone Ester
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Insomnia Disorders, Insomnia Disorder
Comparative Efficacy of BRT and CBT-I for Insomnia
This study evaluates two behavioral treatments for patients with insomnia disorder: Bedtime Restriction Therapy (BRT) and Cognitive Behavioral Therapy for Insomnia (CBT-I).
- Conditions
- Insomnia Disorders, Insomnia Disorder, Insomnia, Insomnia Chronic
- Trial name
- SLEEPwindow (NCT06767137)
- Testing
- Cognitive behavioral therapy for insomnia (CBT-I), Bedtime restriction (BRT)
- Where
- 2 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Christoph Nissen
Parkinson's Disease (PD)
Pilot Study of Robotic Spinal Mobilization in Parkinson's Disease
This interventional pilot study will evaluate the safety and clinical efficacy of robotic spinal mobilization in community-dwelling adults with Parkinson's Disease (PD).
- Trial name
- NCT07376122
- Testing
- BackHug Robotic Spinal Mobilization System
- Volunteers
- 30 people
- Sponsor
- Pacla Medical Limited
Sleep Deprivation
Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period
Short sleep duration confers high cardiovascular and metabolic risk, but lifestyle factors and molecular mechanisms that contribute to increased blood pressure and poor glucose control during short sleep are not completely…
- Trial name
- CRISP (NCT06070194)
- Testing
- Time restricted eating (TRE)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Sleep Deprivation, Sleep Restriction
Acoustic Stimulation During Restricted Sleep After Sleep Deprivation
The purpose of this study is to determine if brief sounds or tones presented within a restricted period of recovery sleep after a period of sleep deprivation will enhance restorative properties and improve performance during a…
- Conditions
- Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance
- Trial name
- NCT05309473
- Testing
- Philips SmartSleep Acoustic Stimulation Device
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Healthy Volunteer
Challenging the Endocannabinoid System in Sleep Restricted Healthy Volunteers to Modulate Physiological Arousal (CANISLEEP) Study
The goal of this study is to learn about the body's response to cannabis based products in sleep deprived people who are currently experiencing anxiety but are otherwise healthy.
- Trial name
- CANISLEEP (NCT07656350)
- Testing
- THC, CBD, THC + CBD
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King's College London
Chronic Insomnia
Effects of Sleep Restriction and Stimulus Control in Chronic Insomnia Patients
The study aims to validate the effect of sleep restriction and stimulus control on improving chronic insomnia patients\' sleep habits and maladaptive sleep behaviors.
- Trial name
- NCT06658184
- Testing
- sleep restriction and stimulus control, sleep hygiene education
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xuanwu Hospital, Beijing
Chronic Insomnia, Overweight/Obesity
Cognitive Behavioral Therapy for Insomnia as an Adjunct to Time-restricted Eating on Weight Loss in Adults With Overweight or Obesity and Chronic Insomnia
Obesity (being overweight due to excess body fat) is a common health condition that increases the risk of developing problems such as diabetes, high blood pressure, and heart disease.
- Trial name
- NCT07770516
- Testing
- Flexible Time-restricted eating group (FTRE), Flexible Time-restricted eating plus cognitive behavioural therapy for insomnia group (CBTI+FTRE)
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Old Adults, Sleep Quality
Kava Aging and Mobility Study
The goal of this clinical trial is to learn if AB-free kava works to improve mobility and physical function in older adults with sleep difficulties. It will also learn about the safety of AB-free kava.
- Conditions
- Old Adults, Sleep Quality, Kava, Mobility Impairment
- Trial name
- NCT07219186
- Testing
- AB-free kava
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Insomnia Chronic, Insomnia Due to Medical Condition
Sleep Well Despite Persistent Pain Symptoms
Background: The prevalence of comorbid insomnia is 8-10 times higher in patients with chronic pain than in the general population.
- Conditions
- Insomnia Chronic, Insomnia Due to Medical Condition, Pain, Chronic
- Trial name
- Sleep-Well (NCT06351839)
- Testing
- Sleep-Well despite persistent pain, TAU (treatment-as-usual)
- Where
- Norway
- Volunteers
- 106 people
- Sponsor
- University of Tromso
Time Restricted Eating, Diet, Mediterranean
Healthy Lifestyles for Bipolar Disorder
The goal of this clinical trial is to compare the effects of two different healthy lifestyles on outcomes for those with bipolar disorder.
- Trial name
- HL (NCT06188754)
- Testing
- Time restricted eating, Mediterranean diet
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, Berkeley
Bipolar Disorder, Time Restricted Eating
Healthy Lifestyles in Bipolar Disorder: Bay Area Study
The goal of this clinical trial is to understand how level of adherence with time-restricted eating (TRE) predicts change in diurnal rhythms (as measured using the amplitude of diurnal peripheral clock gene expression), and how…
- Trial name
- NCT06555406
- Testing
- Time-restricted eating for 8 weeks
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Berkeley