Clinical trials: Sleeplessness
Anxiety, Stress
Non-invasive Auricular Simulation for Exam Anxiety and Depression in University Students
In Spain, depression, anxiety, and stress are highly prevalent in the general population as well as in college students. In college students, Ramón Arbués et al.
- Conditions
- Anxiety, Stress, Insomnia
- Trial name
- AURITEST (NCT06442826)
- Testing
- Non-invasive auricular stimulation
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fundació Tecnocampus Mataró-Maresme
Chronic Insomnia
Zolpidem or Exercise for Insomnia?
Introduction: The prevalence of chronic insomnia in the general population is between 10 and 15%. The therapy commonly prescribed for its treatment is pharmacological, however, there are several non-pharmacological alternatives…
- Trial name
- NCT03160404
- Testing
- Zolpidem, Exercise
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Insomnia
Improving Sleep Using Mentored Behavioral and Environmental Restructuring
The goal of this study is to test potential functional/psychosocial benefits of improved sleep using a program designed to teach nursing facility staff to improve sleep promoting strategies and environment for nursing home…
- Trial name
- SLUMBER (NCT03327324)
- Testing
- Sleep Using Mentored Behavioral and Environmental Restructuring
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Sleep Initiation and Maintenance Disorders, Depression
Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.
- Trial name
- NCT00227942
- Testing
- Estrogen Replacement Therapy, Zolpidem
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hadine Joffe, MD
Bladder Function
Pilot Trial in Sleep Laboratory Setting to Compare the Physiology of Night Time Bladder Function in Subjects With Overactive Bladder (OAB) Versus Subjects That Have Insomnia and Healthy Normal Subjects
This is an observational, physiology pilot study of subjects with overactive bladder, insomnia and normal subjects. No study drug will be given. All subjects will complete a one week sleep diary and a 3-day bladder diary.
- Trial name
- Nocturia Plt 1 (NCT01029015)
- Testing
- cystometry, polysomnography
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Chronic Low-back Pain, Insomnia
Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study
Our goal is to observational study is to determine feasibility of partial sleep restriction in individuals with CLBP+I and correlation findings with features of central sensitization.
- Conditions
- Chronic Low-back Pain, Insomnia, Sleep
- Trial name
- NCT07008924
- Testing
- No intervention is provided. We monitor natural recovery to full sleep.
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Insomnia
Study to Investigate the Effects of Melatonin, Temazepam & Zolpidem on Sleep EEG in Men and Women
This study has been designed to compare the effects of melatonin with those of drugs (temazepam and zolpidem) regularly prescribed for the treatment of insomnia, in healthy, middle-aged volunteers.
- Trial name
- NCT00940550
- Testing
- Prolonged-release melatonin, Temazepam, Zolpidem
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Insomnia
Follow-up of a Study Examining Sleep Management in United States Veterans
The first part of the pilot study, as detailed in Unique Protocol ID No. 27522, is a randomized clinical trial that compares the effects of a mind-body bridging program with a sleep hygiene program to improve sleep quality in…
- Trial name
- NCT00935337
- Testing
- Mind-Body Bridging Program, Sleep Hygiene
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Utah
Anxiety Disorder, Insomnia
A Multicenter Randomized Controlled Study of Pulse Magnetotherapy Combined Medication in Anxiety Combined With Insomnia
The goal of this clinical trial is to explore the therapeutic effect of pulse magnetic therapy system combined with drug therapy on patients with anxiety and insomnia. The main questions it aims to answer are: 1.
- Trial name
- NCT05705830
- Testing
- Pulse magnetic therapy, Selective serotonin reuptake inhibitors （SSRI）
- Where
- 3 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Insomnia, Health Adult Subjects
Does Style Matter: Comparison of Moderate- to Low-intensity Styles of Yoga
The goal of this clinical trial is to learn if yoga works to improve sleep and heart health in adults with and without insomnia disorder.
- Conditions
- Insomnia, Health Adult Subjects, Insomnia Disorder, Heart Health Markers
- Trial name
- NCT07638267
- Testing
- Vinyasa yoga, Gentle yoga, Non-active control
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Caitlin Cheruka
Insomnia, Sleep Initiation and Maintenance Disorders
Assessment of Smartwatch SAMSUNG to Monitor Sleep Quality: an Observational Prospective Study - SleepEx2 Protocol
The goal of this study is to learn if a smartwatch is effective to identify factors related to sleep quality and habits of adults (30 years old or more), enabling the improvement and/or creation of instruments to assess overall…
- Conditions
- Insomnia, Sleep Initiation and Maintenance Disorders, Health Status, Wearable Electronic Devices
- Trial name
- SLEEP-EX2 (NCT06363656)
- Testing
- Wears the smartwatch during the sleep time to capture sleep characteristics and answer questionaires
- Where
- Brazil
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Sleep Disorder, Healthy
Effects of Experimental Sleep Disturbances on Receptor Function of Study Drug
The overall goal of this project is to determine whether common sleep disturbance patterns, sleep continuity disturbance (SCD) and Sleep Fragmentation (SF), alter cerebral study drug receptor availability, drug-based analgesia…
- Trial name
- Sleep-MOR (NCT04299490)
- Testing
- Sleep Fragmentation, Sleep Continuity Disruption, Undisturbed Sleep
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Insomnia, Menopause
No More Sleepless Nights in Perimenopause
The goal of the clinical trial is to learn if Hormone Replacement Therapy (HRT) and Cognitive Behavioral Therapy (CBT-I) can treat insomnia in menopausal women.
- Trial name
- NCT06497894
- Testing
- Cognitive Behavioural Therapy for Insomnia (CBT-I), Hormone Replacement Therapy (HRT), Sleep Hygiene
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Type 2 Diabetes, Insomnia
Cognitive Behavioral Therapy for Insomnia in Type 2 Diabetes Mellitus
This study will explore the effects of cognitive behavioral therapy for insomnia (CBTI) compare to health educations in patients with type 2 diabetes (T2DM) with insomnia symptoms.
- Trial name
- NCT06202742
- Testing
- cognitive behavioral therapy for insomnia, Health education
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Sleep Fragmentation, Poor Quality Sleep
Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production
Nocturia is prevalent in older adults and it vastly reduces quality of life. Yet its treatment remains inadequate because its causes are not well understood, especially nocturnal polyuria or increased urine production at night.
- Conditions
- Sleep Fragmentation, Poor Quality Sleep, Nocturia, Nocturnal Enuresis
- Trial name
- NCT03883724
- Testing
- Brief behavioral treatment of insomnia (BBTI), Information-only control (IC)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Insomnia
Driving Performance After Middle of the Night Administration of 3.5 mg Zolpidem Tartrate Sublingual Tablet
A study in healthy volunteers of the next morning driving performance after middle-of-the-night dosing of 3.5 mg zolpidem tartrate sublingual tablet, a sleep aid.
- Trial name
- NCT01106859
- Testing
- zopiclone, zolpidem tartrate sublingual tablet
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Transcept Pharmaceuticals
Insomnia
Digitally-Assisted Brief Behavioral Treatment for Insomnia in College Students
The study is a single-blind study, parallel randomized controlled trial method. The purpose of this study was to explore the effectiveness of the mobile version of Application based Brief Behavioral Treatment for Insomnia…
- Trial name
- NCT07114302
- Testing
- Interactive E-book BBTI Group, BBTI-APP Group
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Insomnia
Insomnia in Older Adults: Impact of Personalized, Diet-Induced Alterations in the Microbiota
Insomnia is a chronic mental health condition characterized by difficulty initiating and maintaining sleep with a prevalence of over 50% in Israeli adults ages 65 and above.
- Trial name
- NCT03085446
- Testing
- PDM nutritional intervention, General information on nutrition and health
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Insomnia
Open-Label Study of Bioavailability of E2006 Tablet Versus Capsule Formulations
This is a single-center, open-label, randomized crossover study being conducted in three cohorts of healthy adult subjects. Approximately 36 subjects will be randomized to one of three cohorts (approximately 12 subjects per…
- Trial name
- NCT01673880
- Testing
- E2006
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Sleep Control Condition, Insomnia Symptoms Induction Condition
Pain Sensitization and Habituation in a Model of Experimentally-induced Insomnia Symptoms
The main purpose of this study is to learn about the effects of repeated exposure to sleep disruption (3 cycles of sleep disruption, each consisting of three days in a row where sleep is shortened and disrupted, followed by a…
- Trial name
- NCT02484742
- Testing
- Insomnia symptom induction
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center