Clinical trials: Slow Breathing
Heart Failure
Short Term Hemodynamic Effects of Controlled Slow Breathing With Biofeedback in Patients With Heart Failure
Heart failure is associated with faster breathing, which has a negative impact on the functioning of the heart. This leads to fatigue, shortness of breath, and exercise intolerance.
- Trial name
- NCT00971386
- Testing
- Slow breathing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Breathing Rate
Coherence Breathing Before Cardiopulmonary Exercise Testing
This randomized crossover trial will examine the acute effects of pre-exercise coherence breathing on cardiopulmonary exercise responses in recreationally active adults.
- Trial name
- NCT07650279
- Testing
- Coherence Breathing, Spontaneous Breathing
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Human Performance Lab of Monmouth University
Physiological Stress
Impact of Breathing Interventions on Stress Markers
The goal of this clinical trial is to examine the effects of slow breathing breathing on markers of stress in healthy college aged individuals.
- Trial name
- NCT05825846
- Testing
- Virtual- reality active shooter drill
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas State University
Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation
Health Outcomes With CPAP or NIV in Patients With COPD and a Sleep Related Breathing Disorder
Chronic obstructive pulmonary disease (COPD) is a chronic lung disease affecting an estimated 1 in 10 Canadians. Symptoms include persistent shortness of breath, cough and sputum production.
- Conditions
- Chronic Obstructive Pulmonary Disease, Sleep Related Hypoventilation, Obstructive Sleep Apnea, Hypoventilation
- Trial name
- NCT05623709
- Testing
- Positive airway pressure with continuous positive airway pressure or noninvasive ventilation
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Normobaric Hypoxia, Hypoventilation
Influence of Hypoxic, Normobaric and Hypobaric Training on the Immunometabolism of Post-covid-19 Athletes
COVID-19 has significantly impacted sports globally, with event postponements, training disruptions, and wide-ranging concerns. SARS-CoV-2 infection can result in hyperinflammation and cardiopulmonary changes, with hypoxia as an…
- Conditions
- Normobaric Hypoxia, Hypoventilation, Normoxia
- Trial name
- NCT06128941
- Testing
- Repeated sprint
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Hypertension
Yoga in Altering Mechanistic Outcomes in Hypertension
The proposed study will assess the effects of yoga postures and slow, deep breathing in altering oxidative stress, vascular function, and blood pressure.
- Trial name
- NCT05158205
- Testing
- Yoga, Slow, deep breathing, Control breathing
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Texas State University
CSF Circulation
Influence of Yogic Breathwork on CSF Circulation
The purpose of this research study is to determine the influence of yoga breathing practices on cerebrospinal fluid (CSF) circulation, and to find out primarily if a regular practice of 8-week yoga breathing would enhance CSF…
- Trial name
- CSF (NCT03858309)
- Testing
- Breathing Group 1, Breathing Group 2
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Congenital Central Hypoventilation Syndrome (CCHS)
Identifying Biomarkers & Dysregulated Biological Pathways in Blood and Urine of Congenital Central Hypoventilation Syndrome (CCHS) Patients
The CCHS study is a prospective, open-label, monocentric, interventional study with diagnostic and prognostic objectives, conducted in two phases.
- Trial name
- CCHSBiomarkers (NCT06997146)
- Testing
- Blood and Urine Sampling, Polysomnography, lung function tests
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy Adult Participants
The Effect of A Slow-Paced Breathing Intervention on Heart Rate Variability, Stress, and Dysfunctional Breathing Patterns in Healthy Young Adults
The primary aim of this study is to evaluate the effects of a controlled breathing exercises-on autonomic nervous system functions (HRV) and perceived stress levels in healthy young adults with dysfunctional breathing patterns.
- Trial name
- SPB-HRV-RCT (NCT07874750)
- Testing
- slow-paced breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Drug Overdose, Opioid-Related Disorders
Development of an Algorithm That Predicts Hypoventilation Due to an Opioid Overdose
RTM Vital Signs, LLC is developing a miniature wearable tracheal sound sensor that communicates with a cell phone containing a machine-learning diagnostic algorithm designed to detect and predict the onset of mild, moderate, and…
- Trial name
- NCT03845699
- Testing
- Diagnostic algorithms that detects/predicts hypoventilation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RTM Vital Signs, LLC
Congenital Central Hypoventilation Syndrome
Late-onset Congenital Central Hypoventilation Syndrome and the Mutation of Phox2B Gene
Congenital central hypoventilation syndrome (CCHS) is a rare disorder of respiratory control characterized by ventilatory impairment that results in arterial hypoxemia.
- Trial name
- CCHS (NCT01225679)
- Testing
- positive airway pressure, Non-invasive mechanic ventilation
- Where
- Brazil
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Quality of Life, Behavior
Breathing and Decision-Making
The study aims to investigate how slow breathing with prolonged exhalation (i.e., ProlEx breathing) modulates decision-making under risk in healthy participants.
- Conditions
- Quality of Life, Behavior, Stress, Psychological
- Trial name
- ProlEx-MRI (NCT05936684)
- Testing
- Breathing with prolonged exhalation (ProlEx) during risky decision-making, Normal breathing (Eupnea/Control) during risky decision-making
- Where
- Germany
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Metabolic Syndrome, Obesity Hypoventilation Syndrome
Obesity-hypoventilation in Metabolic Syndrom Patients
The purpose of the study is to determined the prevalence of obesity-hypoventilation syndrome in patients with metabolic syndrom.
- Conditions
- Metabolic Syndrome, Obesity Hypoventilation Syndrome, Capnography
- Trial name
- NCT04839419
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- SOS Oxygene Mediterranee
Adult
LasaiON is an Evidence-informed, Multimodal Self-regulation Program Designed to Reduce Emotional Distress and Strengthen Stress-regulation Skills by Combining Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) With Breathing Supported by Heart-rate Variability Biofeedback (HRV-B; emWave).
The goal of this clinical trial is to evaluate whether the LasaiON program, which combines transcutaneous auricular vagus nerve stimulation (taVNS) with breathing supported by heart rate variability biofeedback (HRV-B; emWave)…
- Trial name
- LasaiON (NCT07498881)
- Testing
- LasaiON
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Hypoventilation
Positive Pressure and Gravity Affect Volumetric Capnography
Volumetric capnography is an interesting and non-invasive tool for monitoring ventilation in mechanically ventilated patients. The aim of this study was to test the effect of positive pressure ventilation and different body…
- Trial name
- NCT03853057
- Testing
- body positions
- Where
- Argentina
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Normobaric Hypoxia, Hypoventilation
"Living Low - Training High" Methods and Physiological Responses in Well-trained Swimmers
To overcome the lack of knowledge regarding the impact of different "living low, training high" methods on swimming performance, a 4-week intervention will be carried out to determine and compare the effects of three Repeated…
- Conditions
- Normobaric Hypoxia, Hypoventilation, Normoxia
- Trial name
- NCT06253039
- Testing
- Repeated sprint
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Healthy Volunteers
Effects of Breath-Hold vs Standard Interval Training on Fitness in Mountaineers
This study investigated whether adding structured breath-holds to standard interval training improves cardiorespiratory fitness in recreational mountaineers more than interval training alone.
- Trial name
- NCT07703839
- Testing
- Voluntary Hypoventilation Training, Progressive Treadmill Interval Training
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohammadreza Rezaeipour, MD, PhD
Chronic Obstructive Pulmonary Disease
Comparative Effects of ACBT and Slow Expiration in Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is characterized by nonreversible airway obstruction. A diagnosis of COPD is determined by clinical assessment of airflow limitation and symptoms such as cough and wheeze; however, the…
- Trial name
- NCT05922267
- Testing
- ACTIVE CYCLE OF BREATHING TECHNIQUES, SLOW EXPIRATION WITH OPEN GLOTTIS IN LATERAL POSITION
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Obesity, Pulmonary Atelectasis
Effects of PEEP on Heart and Lungs in Obese Subjects
Aim of this study is to better understand pathophysiology of the alteration of respiratory mechanics and cardiovascular function in obese volunteer subjects.
- Conditions
- Obesity, Pulmonary Atelectasis, Obesity Hypoventilation Syndrome, Magnetic Resonance Imaging
- Trial name
- NCT02523352
- Testing
- Non-Invasive Ventilation, Esophageal catheter positioning
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alveolar Hypoventilation Resulting in Hypoxemia
Capnography During Nurse Administered Propofol Sedation
Rationale: The current standard of respiratory monitoring for patients during deep sedation is continuous pulse oximetry with visual assessment of the patient.
- Trial name
- NCT01220765
- Testing
- Capnography
- Where
- Netherlands
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht