Clinical trials: Small Bowel Obstruction
Small Intestine Disease, Small Intestine Cancer
Prospective Collection of PillCam SB3 Videos and Raw Data Files for Future Developments (SODA)
Observational, Multicenter, Post-market, Minimal risk, Prospective data collection of PillCam SB3 videos (including PillCam reports) and raw data files and optional collection of Eneteroscopy reports
- Conditions
- Small Intestine Disease, Small Intestine Cancer, Small Intestinal Ulcer Bleeding, Small Intestine Obstruction
- Trial name
- SODA (NCT03771508)
- Where
- 30 sites in United States
- Volunteers
- 3,712 people
- Sponsor
- Medtronic - MITG
Small Bowel Obstruction, Small Bowel Adhesion
Comparison of Early Operative Treatment and 48 h Conservative Treatment in Small Bowel Obstruction
This study will compare the results of early surgery after 12 h conservative treatment and 48 h conservative treatment of adhesive small bowel obstruction.
- Conditions
- Small Bowel Obstruction, Small Bowel Adhesion, Strangulation of Ileum
- Trial name
- COTACSO (NCT03139149)
- Testing
- Adhesiolysis, X-ray diagnostics, Computer tomography
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Pirogov Russian National Research Medical University
Small Bowel Obstruction
Intrabdominal Pressure in Small Bowel Obstruction as a Possible Predictor for the Need of Operation
Small bowel obstruction (SBO) is a common surgical diagnosis. Most of SBO are related to post operative adhesions and most of them resolve without the need of surgical intervention.
- Trial name
- NCT01934283
- Testing
- urine folly catheter
- Where
- Israel
- Volunteers
- 125 people
- Sponsor
- Meir Medical Center
Small Bowel Obstruction
Clinical Impacts of Oral Gastrografin Follow Through in Adhesive Small Bowel Obstruction (SBO)
Mini abstract : Altogether 100 patients with 117 episodes of ASBO were randomized into control and gastrografin groups. Eight episodes in eight patients were excluded.
- Trial name
- NCT00738855
- Testing
- Oral Gastrografin, Nothing per os
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Bowel Obstruction Small
Diagnostic Performance of Arterial Time for CT Assessment of Parietal Enhancement Defect for the Diagnosis of Ischemia in Mechanical Small Bowel Occlusions: a Comparative Study With Portal Time
Intestinal obstruction is a frequent cause of emergency room visits and represents about 4-7% of the causes of acute abdominal pain syndrome and up to 30% in adults over 60 years old.
- Trial name
- PORTOGRELE (NCT04880421)
- Where
- France
- Volunteers
- 158 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Intestinal Obstruction
Clinical and Financial Impact of an Evidenced-Based Adhesive Small Bowel Obstruction Management Protocol
This research study is for patients with adhesive small bowel obstruction (ASBO). ASBO is a condition in which the small intestine gets blocked due to scars called adhesions.
- Trial name
- NCT02928458
- Testing
- Omnipaque, MD-Gastroview
- Where
- United States
- Sponsor
- The Guthrie Clinic
Adhesive Small Bowel Obstruction
Comparison of Outcomes of Management of Bowel Obstruction
The Comparison of Outcomes of Management of Bowel Obstruction (COMBO) trial is a patient-level randomized trial of a short course of dexamethasone + supportive care vs supportive care alone for patients with adhesion-related…
- Trial name
- COMBO (NCT07084441)
- Testing
- Dexamethasone, Supportive Care
- Where
- 4 sites in United States
- Volunteers
- 550 people
- Sponsor
- University of Washington
Small Bowel Obstruction
SnapSBO - Small Bowel Obstruction Snapshot Audit
Small bowel obstruction (SBO) and its complications are frequently seen in patients admitted through the Emergency Departments of all acute care hospitals2.
- Trial name
- SnapSBO (NCT05843097)
- Where
- Spain
- Volunteers
- 1,900 people
- Sponsor
- European Society for Trauma and Emergency Surgery
Small Bowel Obstruction, Surgery
Enhanced Recovery Programs and Small Bowel Obstruction
Small bowel obstruction surgery is frequent and would benefit from enhanced recovery programs. While some studies advocate for their feasibility, it has never been proved and prospective studies are required to confirm the…
- Trial name
- RACO (NCT04929275)
- Testing
- Enhanced recovery program
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Small Bowel Obstruction
Study About Contrast Media
Patients hospitalized with adhesive small bowel obstruction (SBO) are randomized to 2 study groups at admission after signing an informed consent form.
- Trial name
- NCT05678023
- Testing
- Effect on contrast media depending on the time of its administratsion
- Where
- Estonia
- Volunteers
- 120 people
- Sponsor
- University of Tartu
Adhesive Small Bowel Obstruction
Predictors of Laparoscopy Conversion in Adhesive Small Bowel Obstruction
The goal of this observational study is to reveal predictors of unsuccessfull laparoscopic intervention in adult patients with adhesive small bowel obstruction.
- Trial name
- NCT07350447
- Testing
- Laparoscopic adhesiolysis, Laparotomic adhesiolysis
- Where
- 7 sites in Russia
- Volunteers
- 170 people
- Sponsor
- Almazov National Medical Research Centre
Small Bowel Obstruction, Frailty
The Utility of Treatment With Nasogastric Tube Placement for Small Bowel Obstruction
Small bowel obstruction (SBO) occurs when the normal movements of the small bowel is obstructed, most commonly due to adhesion related to previous abdominal surgery.
- Conditions
- Small Bowel Obstruction, Frailty, Nasogastric Tube
- Trial name
- NGTUBE-OBS (NCT06262815)
- Testing
- Nasogastric tube placement, Clinical Frailty Scale
- Where
- 8 sites in Sweden
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Daniel Wilhelms
Bowel Obstruction, Artificial Intelligence
Deep Learning-based Artificial Intelligence for the Diagnosis of Small Bowel Obstruction
The study will compare the diagnostic accuracy and time to diagnosis of computed tomography images of patients with suspected intestinal obstruction seen in the emergency room by residents and surgeons, with and without…
- Trial name
- NCT06481358
- Testing
- Artificial intelligence
- Where
- Japan
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Nagoya University
Surgery-Induced Tissue Adhesion, Surgical Adhesions
National Snapshot Study Adhesive Small Bowel Obstruction (ASBO)
Over 63-90% of patients develop peritoneal adhesions after abdominal or pelvic surgery. Which makes it the most common complication after abdominal or pelvic surgery.
- Conditions
- Surgery-Induced Tissue Adhesion, Surgical Adhesions, Adhesion, Tissue
- Trial name
- NCT03786159
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Radboud University Medical Center
Small Bowel Obstruction, Conservative Management
Radiologic Score and Failure of Conservative Management of Adhesive Small Bowel Obstruction
The management of acute adhesive small bowel obstruction remains challenging for the digestive surgeon. The Bologna guidelines recommend that conservative management of aSBO.
- Conditions
- Small Bowel Obstruction, Conservative Management, Imaging
- Trial name
- PREDIFAIL (NCT05517057)
- Where
- France
- Volunteers
- 279 people
- Sponsor
- University Hospital, Angers
SBO - Small Bowel Obstruction
Management of Non Emergency Adhesive Small Bowel Obstruction:
SBO-CHOICE is a prospective, multicenter observational study investigating the management of adhesive small bowel obstruction (ASBO), a condition in which scar tissue (adhesions), usually resulting from previous abdominal…
- Trial name
- SBO- CHOICE (NCT07860177)
- Testing
- Surgical group
- Where
- Italy
- Volunteers
- 690 people
- Sponsor
- Azienda Sanitaria di Firenze
Small Bowel Obstruction
Value of CT-Scan and Oral Gastrografin in the Management of Post Operative Small Bowel Obstruction
Small bowel obstructions are responsible for 2 to 5% of emergency hospital admissions and 20% of all emergency surgical procedures.
- Trial name
- NCT00389116
- Testing
- gastrograffin, water
- Where
- France
- Volunteers
- 242 people
- Sponsor
- University Hospital, Rouen
Small Intestine Disease, Small Intestine Cancer
Data Collection of PillCamTM SB3 Capsule Endoscopy and Device-Assisted Enteroscopy Routine Care Procedures (GPS Study)
A prospective, multicenter, post-market, minimal risk, observational study designed to collect PillCamTM SB3 capsule endoscopy (CE) procedures and subsequent device-assisted enteroscopy (DAE) procedures data (double balloon…
- Conditions
- Small Intestine Disease, Small Intestine Cancer, Small Intestinal Ulcer Bleeding, Small Intestine Obstruction
- Trial name
- NCT05450393
- Sponsor
- Medtronic - MITG
Small Bowel Obstruction
Early Surgery Versus 3 Days Non-surgical Management in Acute Small Bowel Obstruction (SURGI-BOW)
For uncomplicated acute small bowel obstruction (aSBO), the "Bologna guidelines" recommend non-surgical management of 72 hours before considering surgery.
- Trial name
- SURGI-BOW (NCT06065150)
- Testing
- Standard support, Early surgery proposed according to the radiological score
- Where
- 14 sites in France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Angers