Clinical trials: Smoker
E-cigarettes
Acute Response to Cigarette and E-cigarette Smoking Assesed in Exhaled Breath Condensate in Healthy Smokers of Traditional and E-cigarettes
Electronical cigarettes, also known as "e-cigarettes" are a new phenomenon, which steadily wins more aprobation among smokers. However, there exists no much data concerning the effects of acute exposure to electronic cigarettes…
- Trial name
- NCT03153228
- Where
- Poland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Tobacco Use
The Impact of E-liquid Nicotine Content on Reinforcement in Current Smokers
Participants will complete a phone screen and then one laboratory session. After completing in-person screening assessments, eligible participants will complete additional questionnaires.
- Trial name
- NCT03186911
- Testing
- E-liquid sampling and preference assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Lung Cancer
LDCT Screening in Non-smokers in Taiwan
This study utilizes the low dose computed tomography(LDCT) to detect the occurrence of early lung cancer among non-smokers in Taiwan.
- Trial name
- NCT02611570
- Testing
- LDCT
- Where
- 17 sites in Taiwan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Academia Sinica, Taiwan
Dentin Sensitivity
Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients
The main objective of this study is to evaluate the effectiveness and longevity of color and Tooth sensitivity of patients undergoing home whitening peroxide 10% carbamide ( Whiteness Perfect , FGM , Joinville , Santa Catarina …
- Trial name
- BLESMOK (NCT02017873)
- Testing
- Peroxide Carbamide 10% - Dental bleaching treatment
- Where
- 2 sites in Brazil, Chile
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Chile
Smoking, Tobacco, Smoking (Tobacco) Addiction
Effects of Nicotine in Tobacco Smokers
This study will examine mechanisms linking Obsessive-Compulsive Disorder symptomatology to tobacco dependence.
- Trial name
- NCT03651869
- Testing
- Cigarette 1, Cigarette 2, Patch 1
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Smoking, Non-smoking
Smoking Research Study
The purpose of this study is to develop a fit-for-purpose biochemical verification tool that can be used to detect concomitant use of a few (less than 5) conventional cigarettes.
- Trial name
- NCT01465880
- Testing
- Part A
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking Cessation
Strategies to Promote Cessation in Smokers Who Are Not Ready To Quit
To our knowledge, no study has evaluated the independent effects of motivational interviewing and rate reduction, individually versus in combination, for motivating smokers who are not ready to quit (SNRTQ) to increase both quit…
- Trial name
- PACE (NCT02905656)
- Testing
- Brief Advice, Motivational Interviewing, Rate Reduction
- Where
- United States
- Volunteers
- 903 people, healthy volunteers welcome
- Sponsor
- University of Virginia
COPD, Healthy Smoker
SLP Model Development in the Diagnosis of COPD Patients
This is an observational, comparative, multicentre study to develop a model for the Thora3Di™ against standard practice in patients who are undergoing investigation for COPD.
- Trial name
- SLPCOPD (NCT04584801)
- Testing
- Structured Light Plethysmography
- Where
- 7 sites in United Kingdom
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Pneumacare Ltd
Cardiovascular Diseases
Chronic and Acute Effects of Smoking on the Left and Right Ventricular Relaxation in Young Healthy Smokers
Impairment of relaxation, the early phase of ventricular diastole is the first stage of heart diastolic dysfunction. Left ventricular diastolic function can be determined noninvasively by Echo- Doppler - derived mitral valve flow…
- Trial name
- NCT00395928
- Where
- Poland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Cancer of Head and Neck, Smoking
Assessment of Early Genetic Changes in Smokers
This study will look at the genetic profile of cells taken from the oral cavity of healthy college students who smoke and who do not smoke cigarettes.
- Trial name
- NCT00200408
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Smoking Cessation, Harm Reduction
Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes
This study will evaluate a reward devaluation strategy in which smokers use the JUUL e-cigarette immediately before any combustible cigarettes (CCs) are smoked.
- Conditions
- Smoking Cessation, Harm Reduction, E-Cig Use, Cigarette Smoking
- Trial name
- RECON (NCT04188197)
- Testing
- JUUL
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Smoking, Smoking Cessation
Culturally Specific Interventions: African American Smokers
The investigators expect that a culturally specific group intervention targeting African American smokers will result in greater smoking cessation rates compared to a standard intervention.
- Trial name
- SB2 (NCT01811758)
- Testing
- Culturally Specific CBT, Standard CBT
- Where
- United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- University of Miami
Nicotine Addiction, E-Cig Use
Sex Differences in E-cig Perception: Study 1
The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.
- Conditions
- Nicotine Addiction, E-Cig Use, Cigarette Smoking, Sex Differences
- Trial name
- NCT05432830
- Testing
- E-liquid Flavor 1, E-liquid Flavor 2, E-liquid Flavor 3
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking, Prevention
Celecoxib as a Chemopreventive Agent in Current and Former Smokers
The purpose of this study is: To examine the effect of celecoxib treatment on Ki-67 expression, a marker of cell proliferation, in the bronchial epithelium of current and former smokers.
- Trial name
- NCT00981201
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking
A Randomized Controlled Trial to Test the Effect of a Smartphone Quit Smoking Intervention on Young Adult Smokers
The primary aim of this study will be to determine the effectiveness of a smartphone delivered app for young adult smokers on quitting smoking.
- Trial name
- NCT01983150
- Testing
- Crush the Crave Application, On the Road to Quitting - Self Help
- Where
- Canada
- Volunteers
- 1,601 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Smoking Cessation
Biomarkers of Molecular Risk in Smokers
Doctors at MSKCC are doing this research study to see if smokers are interested in the idea that genes might be markers of cancer risk, and to see if smokers would want to learn this information about their risk if it were…
- Trial name
- NCT00598143
- Testing
- Vignette, questionnaires and Saliva Samples, Urine Collection, Smoking cessation treatment
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Smoking
Airway and Pulmonary Vascular Endothelial Function in Healthy Smokers: Effect of Inhaled Glucocorticosteroid Treatment
The purposes of the present proposal are to 1) compare inhaled albuterol-induced changes in airway blood flow (Qaw), and in CO and Ppas in healthy current smokers and lifetime non-smokers as an index of endothelial function in…
- Trial name
- smoker3 (NCT02141633)
- Testing
- echocardiogram plus albuterol, airway blood flow plus albuterol, Fluticasone propionate
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Miami
Healthy
Cigarette Smoke and Susceptibility to Influenza Infection
This study will be a descriptive comparison of the effects of live attenuated influenza virus (FluMist) on nasal inflammation and oxidative stress in healthy young adults who are not exposed to smoke vs smokers.
- Trial name
- NCT00448617
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tobacco Use Disorder, Smoking Cessation
Development of a mHealth Intervention for Ambivalent Smokers
The current pilot study will assess the feasibility and acceptability of a novel mHealth app designed for people who are ambivalent about quitting smoking.
- Conditions
- Tobacco Use Disorder, Smoking Cessation, Motivation, Behavior, Smoking
- Trial name
- NCT04560868
- Testing
- Control mHealth program, Experimental mHealth program, Nicotine patch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Healthy
A Phase 1 Study To Investigate The Pharmacokinetics, Safety And Tolerability Of CP-601,927 In Healthy Japanese Subjects
This Phase 1 study is the first clinical trial to be conducted in Japanese subjects. The pharmacokinetics, safety and tolerability of single and multiple doses of CP-601,927 will be evaluated in Japanese, healthy, non-smoking…
- Trial name
- NCT01396135
- Testing
- CP-601,927
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer