Clinical trials: Smoking, Tobacco
Vaping, Lung Diseases
The e-BILD Study: Effects of E-cigarettes on Lung Health in Teenagers.
Electronic nicotine delivery systems (ENDS/e-cigarettes/vaping) are increasingly popular among teenagers around the world. The safety and potential adverse effects of ENDS in this population are largely unknown.
- Trial name
- e-BILD (NCT05105555)
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy Adult Participants
Urban Exposome and Biological Age
The goal of this observational study is to evaluate the impact of the urban exposome, including air pollution and lifestyle-related stressors, on biological aging, inflammatory pathways, oxidative stress, and DNA methylation…
- Trial name
- IDEA (NCT07817836)
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- University of Pavia
Smokers, Vaping
Persistence of Oral DNA Adducts in Smokers and Vapers
This study aims to better understand what damage caused to oral cells from smoking and vaping might be important in the formation of oral cancers.
- Conditions
- Smokers, Vaping, Healthy Volunteers
- Trial name
- NCT06983392
- Testing
- Abstain from smoking/vaping
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Pregnancy, Smoking Cessation
SmokefreeMOM: Reaching Pregnant Smokers With Health Information Via Text Messaging
Despite the great health benefits associated with smoking cessation in pregnancy to both mother and baby, few studies to date have examined the applications of text messaging or other communication technologies for smoking…
- Trial name
- SmokefreeMOM (NCT02412956)
- Testing
- SmokefreeMOM Text
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- George Washington University
Tobacco Use Disorder
The Study of AZD8529 for Smoking Cessation in Female Smokers
To evaluate the efficacy and safety of AZD8529 for smoking cessation in female smokers.
- Trial name
- NCT02401022
- Testing
- AZD8529
- Where
- 9 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Dependence
The Interplay Between Addiction to Tobacco Smoking and Sleep Quality Among Healthy Adults
Tobacco smoking is a major health problem, leading to considerable morbidity and mortality due to cancer, impaired pulmonary function, and cardiovascular diseases.
- Trial name
- NCT04265339
- Testing
- Smoking cessation
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Max Stern Academic College Of Emek Yezreel
Nicotine Dependence, Nicotine Withdrawal
Progesterone and Brain Imaging Study
Male and female smokers were recruited to undergo 2 phases of smoking cessation. Each phase was 4 days long and involved 3 brain-imaging scans, blood draws and an intervention involving progesterone or a matched placebo.
- Trial name
- NCT01954966
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Squamous Cell Carcinoma of the Head and Neck
Study of Olaparib With Radiation Therapy and Cetuximab in Advanced Head and Neck Cancer With Heavy Smoking History
This is a research study that plans to learn more about the safety and tolerability of an investigational drug called Olaparib, in combination with radiation therapy and cetuximab.
- Trial name
- NCT01758731
- Testing
- Olaparib, Cetuximab, Radiation Therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Smoking, Tobacco, Placenta Diseases
Effects of Smoking on Placenta and Lactation
Maternal smoking during pregnancy although it is known to be associated with fetal growth restriction, it's effect on postpartum breastfeeding is not yet clear.
- Conditions
- Smoking, Tobacco, Placenta Diseases, Breastfeeding, Fetal Conditions
- Trial name
- NCT06456645
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Smoking Cessation
Provoked Craving Relief Study by NRT
This study is designed to assess the ability of the mint nicotine mouth strip to relieve provoked cigarette craving in light smokers compared to nicotine lozenge and nicotine gum.
- Trial name
- NRT (NCT01476202)
- Testing
- nicotine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Passive Smoking, Tobacco Smoke Pollution
Educational Models for Tobacco Exposure Awareness
This is a randomized controlled trial comparing the effects of peer education and traditional education on increasing knowledge and awareness of secondhand and thirdhand tobacco smoke exposure among geriatric care program…
- Conditions
- Passive Smoking, Tobacco Smoke Pollution, Health Education, Peer Group Guidance
- Trial name
- NCT07473245
- Testing
- Peer Education, traditional education
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Smoking Cessation
Chat-based Support for Preventing Smoking Relapse
This pilot trial aims to evaluate the effectiveness of chat-based instant messaging support in preventing smoking relapse in recent tobacco abstainers.
- Trial name
- NCT04409496
- Testing
- Chat-based instant messaging support, SMS message support, Self-help booklet
- Where
- Hong Kong
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking ( Cigarette)
Effect of Buteyko Breathing Exercise Combined With Postural Stability Exercises on Maximal Oxygen Consumption in Young Adult Smokers
Background: Smoking is one of the most significant risk factors for respiratory diseases, affecting both lung function and overall respiratory health.
- Trial name
- BBE PSE VO2max (NCT07257783)
- Testing
- Buteyko breathing exercise combined with postural stability exercises
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Yasmeen Alaa Abd El-Hamied Ahmeed
Asthma
Disclosure of Smoking in Adolescents With Asthma
This is an exploratory randomised matched cohort pilot study. It is hypothesised that adolescents (aged 13-16 years) with asthma attending a secondary care outpatient asthma clinic, will disclose their smoking status to a doctor…
- Trial name
- NCT03047902
- Testing
- Group 1 - Parents will be present for the Questionnaire., Group 2- Parents will not be present for the Questionnaire
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Tobacco Use Disorder
Effects of GTS-21 on Smoking Behavior and Neurocognitive Functions
Attempts to quit cigarette smoking are often accompanied by negative mood and problems in attention and memory. These effects, in turn, may contribute to smoking relapse.
- Trial name
- NCT02432066
- Testing
- GTS-21
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Tobacco Dependence, Tobacco Smoking
Smoke-free Home Study in Subsidized Housing
Comprehensive smoke-free policies have the potential to substantially reduce tobacco-related disparities among populations in subsidized housing.
- Trial name
- NCT06170437
- Testing
- Smoke-free home resident intervention, Lay Health Worker coaching
- Where
- United States
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation
A Study Evaluating The Absorption Of Varenicline Into The Body From A Varenicline Patch Applied To The Skin
This study will evaluate the single-dose pharmacokinetics, safety, and tolerability of a varenicline patch applied to the skin.
- Trial name
- NCT01013454
- Testing
- varenicline free base patch
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Smoking Cessation, Electronic Cigarette
Efficacy and Safety of E-cigarettes for Smoking Cessation in Middle-aged Heavy Smokers
Abstract Rationale. Electronic cigarette use is increasing at an exponential rate in Finland and internationally. The health consequences of vaporised aerosols in electronic cigarettes are largely unknown especially in a long…
- Trial name
- EFFECT (NCT03235505)
- Testing
- Nicotine, Varenicline Tartrate, Motivational Interview
- Where
- Finland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Lung Cancer, Smoking Behaviors
Health Opportunities and Promoters of Equitable Screening for Lung Cancer
The goal of this clinical trial is to promote lung cancer screening (LCS) uptake among Hispanic current and former smokers. The main questions it aims to answer are: What barriers do current and former Hispanic smokers face in…
- Conditions
- Lung Cancer, Smoking Behaviors, Diagnosis
- Trial name
- HOPES (NCT05784922)
- Testing
- Educational Lung Cancer Screening (LCS) Video
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Massachusetts General Hospital
Smoking
Effectiveness of the American Lung Association Reactive Anti-Smoking Telephone Help Line in Illinois
An estimated 47 million adult Americans smoke. The American Lung Association has launched a reactive telephone help line to assist in smoking cessation.
- Trial name
- QUITLINE (NCT00749151)
- Testing
- telephone counseling
- Where
- United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Southern Illinois University
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