Clinical trials: Smoking Behaviors
Chronic Obstructive Pulmonary Disease (COPD), Smoking
The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and Disease
Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD, commonly known as chronic bronchitis and emphysema).
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Smoking, Smoking Cessation, Chronic Bronchitis
- Trial name
- NCT00974064
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Vaping
Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot Study
The purpose of this study is to assess the effects of non-invasive vagus nerve stimulation (nNVS) on cognitive functioning in the users of e-cigarettes or vaping products.
- Trial name
- nVNS (NCT06804109)
- Testing
- Active nVNS, Control nVNS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Temple University
Cigarette Smoking
E-Cigarettes and Financial Incentives to Promote Tobacco Harm Reduction Among Adults Accessing Shelter Services
This randomized controlled trial evaluated the feasibility and potential efficacy of 1) e-cigarette switching (EC) or 2) e-cigarette switching + financial incentives for combustible cigarette cessation (EC+FI)
- Trial name
- EXCHANGE (NCT03743532)
- Testing
- E-cigarette Switching, Financial Incentives
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking Cessation, Weight Loss
Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain
The purpose of this research study is to better understand (1) why people gain weight when they quit smoking and (2) whether certain types of smoking cessation (i.e.
- Trial name
- NCT02906787
- Testing
- BAS+, SC
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Nicotine Dependence
Study on Smoking Cessation and Cost Outcomes in the Duke Smoking Cessation Program
The purpose of this study is to conduct an observational assessment of natural outcomes within the Duke Smoking Cessation Program (DSCP), "Quit at Duke." This assessment will include information regarding abstinence rates…
- Trial name
- NCT02845687
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Duke University
Electronic Cigarette Use, Plaque Induced Gingivitis
Efficacy of Oral Hygiene Instructions on Proinflammatory Cytokines Among Cigarette Smokers and Individuals Vaping Electronic Cigarettes During Plaque Induced Gingivitis (Clinical Trial)
To evaluate the level of proinflammatory cytokines in individual vaping electronic cigarette in gingivitis patients. Can vaping affects the proinflammatory cytokines level in diseased individuals? Group I: cigarette smoker with…
- Trial name
- NCT06177158
- Testing
- oral hygiene instructions
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Smoking Behaviors
Evaluation of a Novel mHealth Intervention for People Who Are Ambivalent About Quitting Smoking
The goal of this study is to compare the effectiveness of two smoking cessation programs to determine which better helps people change their smoking behavior, the control or the experimental intervention? Both interventions…
- Trial name
- GEMS (NCT07459621)
- Testing
- Control Intervention, Experimental Intervention
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Kaiser Permanente
Smoking
Neuroimaging Reward, Behavioral Treatment, and Smoking Cessation
The goal of this study is to evaluate the effects of a smoking cessation intervention combining behavioral treatment with low nicotine cigarettes on neuroimaging measures of reward function and smoking cessation outcomes.
- Trial name
- NCT02927847
- Testing
- Nicotine Patch, SPECTRUM Nicotine Research Cigarettes (.03 mg), Behavioral Activation
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Maggie M Sweitzer, PhD
Smoking Cessation
Novel Smoking Cessation Drug for Schizophrenia
The investigators will evaluate effects of a novel drug that improves nicotinergic receptor function vs. placebo on short-term smoking abstinence in smokers with schizophrenia who have a high interest in quitting.
- Trial name
- TRENDS (NCT02230384)
- Testing
- Active JNJ Drug
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- K.N. Roy Chengappa
Cardiovascular Risk Factor
SEMEiotic Oriented Technology for Individual's CardiOmetabolic Risk Self- assessmeNt and Self-monitoring
Cardio-metabolic risk factors include obesity, physical inactivity, smoke, alcohol abuse, high blood lipids or sugar and arterial hypertension.
- Trial name
- SEMEOTICONS (NCT02818504)
- Testing
- Wize Mirror
- Where
- 3 sites in France, Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istituto di Fisiologia Clinica CNR
Tobacco Use
Choose2Quit: Improving Equity in Smoking Cessation for Low Income Adults
The goal of this study is to evaluate the effectiveness of a tobacco treatment navigator to improve primary care patient engagement in tobacco cessation support. We compare an ask, advise and connect to the quitline approach vs.
- Trial name
- NCT05612152
- Testing
- Referral to Quitline, Choose2Quit
- Volunteers
- 1,600 people
- Sponsor
- Oregon Health and Science University
Pregnancy, Smoking Cessation
Efficacy of Proactive Telephone Counseling for Pregnant Smokers Enrolled in a Managed Care Organization
The principal objective is to test whether offering pregnant smokers a proactive telephone counseling program throughout pregnancy and for 2 months postpartum increases the rate of smoking cessation at end of pregnancy and 3…
- Trial name
- NCT00181909
- Testing
- Smoking cessation counseling delivered by telephone
- Where
- 2 sites in United States
- Volunteers
- 434 people
- Sponsor
- Massachusetts General Hospital
Smoking
Development of Positive Psychotherapy for Smoking Cessation
The primary objective of this study is to test a manualized adaptation of positive psychotherapy (PPT) for smoking cessation (PPT-S).
- Trial name
- NCT01451814
- Testing
- Positive Psychotherapy for smoking cessation, Nicotine polacrilex, Relaxation training
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Brown University
Smoking Cessation
ChatGPT-Supported Text Messaging Program for Smoking Cessation
The current research proposal aims to explore how a purpose driven LLM ChatGPT chatbot, BeFreeBot, might enhance an evidence-based text messaging smoking cessation program, BeFree.
- Trial name
- NCT07079306
- Testing
- BeFree+Bot, BeFree
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- George Washington University
Smoking Cessation, Weight, Body
Daily Liraglutide for Nicotine Dependence
This clinical research trial examines the effects of the GLP-1 receptor agonist liraglutide on smoking behavior, food intake, and weight gain.
- Trial name
- DAL (NCT03712098)
- Testing
- Liraglutide, Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rebecca Ashare
Tooth Loss
Tooth Loss Rate and Its Associated Factors: a Retrospective Cross-sectional Study With up to 50 Years of Follow-up.
This study will evaluate, in an adult population (n=448) previously diagnosed with gingivitis and/ or periodontitis, the tooth loss rate and its potential associated factors such as diabetes, smoking, bruxism, cardiovascular…
- Trial name
- NCT06578806
- Volunteers
- 448 people
- Sponsor
- Saint-Joseph University
Tobacco Use, Smoking Cessation
Can Cognitive Behavioural Therapy Help Incarcerated Men Quit Smoking? Efficacy and Predictors of Treatment Outcomes
The goal of this clinical trial is to evaluate whether a brief group-based psychological intervention using cognitive-behavioral therapy (CBT) helps people in prison quit smoking.
- Conditions
- Tobacco Use, Smoking Cessation, Cognitive Behavioral Therapy, Prisoners
- Trial name
- PriSanTabac (NCT06873009)
- Testing
- Cognitive-Behavioral Therapy (CBT) for Smoking Cessation, Health Education Session on Tobacco Use
- Where
- France
- Volunteers
- 202 people
- Sponsor
- Centre Hospitalier St Anne
HIV Positive, Marijuana Smoking
Medical Marijuana Use in HIV+ Patients Prospective Cohort Study
The investigators are interested in understanding personal factors such as medical conditions and mental health, as well as social and economic factors, that influence marijuana (and other substance) use in HIV-positive patients.
- Trial name
- MMC-1 (NCT01536899)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Wayne State University
Nicotine Dependence
Breath Carbon Monoxide and Cotinine as Biomarkers to Distinguish Smokers From Nonsmokers
Background: Self-report and biochemical verification are used to determine smoking status in treatment trials and clinical research. Each method has merits and limitations that make it appropriate for particular situations.
- Trial name
- NCT01031121
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Use Disorder
Combination Pharmacotherapy for Smoking Cessation Among Methadone Patients
The purpose of this pilot study is to examine the effects of combined pharmacotherapy (Zyban/NRT)/behavioral treatment on smoking cessation among methadone maintenance therapy patients.
- Trial name
- NCT00060814
- Testing
- Combined intervention
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- National Institute on Drug Abuse (NIDA)