Clinical trials: Smoking Cessation
Tobacco Use
Pilot Randomised Controlled Trial of ToQuit Intervention in India
Tobacco use is associated with high mortality, and a range of morbidities including cancer, and lung and cardiovascular diseases.
- Trial name
- ToQuit (NCT04782453)
- Testing
- ToQuit, a technology delivered tobacco cessation intervention, Tobacco quitting helplines
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sangath
Smoking Cessation, Mental Illness
Mobile App for Smoking Cessation and Mental Health
Adults with serious mental illness (SMI) represent 5% of the United States population, yet account for 30% of all cigarettes smoked and are 2 to 3 times more likely to be dependent on nicotine compared with the general…
- Trial name
- NCT04887558
- Testing
- Smart-T Mental Health and NRT, Smart-T Mental Health+ and NRT, QuitGuide + NRT
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Tobacco Smoking
Smoking Interventions in the General Population
The study takes up two problems: 1) Little research exists about general population interventions for smokers not ready to quit within the foreseeable future.
- Trial name
- NCT00678938
- Testing
- Smoking abstinence oriented expert system intervention, Smoking reduction oriented expert system intervention
- Volunteers
- 1,462 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Tobacco Smoking, Second Hand Tobacco Smoke
eCEASE to Support Treatment for Parental Tobacco Use
The proposed project aims to develop an innovative and disseminable electronic health record (iEHR)-based approach that supports optimal primary care workflows to routinely screen families for tobacco and e-cigarette use, address…
- Conditions
- Tobacco Smoking, Second Hand Tobacco Smoke, Smoking Cessation
- Trial name
- eCEASE (NCT04974736)
- Testing
- iEHR + Navigator
- Where
- United States
- Volunteers
- 817 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cigarette Smoking
Using Computers to Assist in Parental Smoking Cessation in a Pediatric Setting
The CHICA system is a clinical decision support system that uses adaptive turnaround documents to provide point-of-care information to clinicians.
- Trial name
- NCT01334216
- Testing
- CHICA Smoking Cessation Module
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Indiana University
Smoking Cessation
ChatGPT-Supported Text Messaging Program for Smoking Cessation
The current research proposal aims to explore how a purpose driven LLM ChatGPT chatbot, BeFreeBot, might enhance an evidence-based text messaging smoking cessation program, BeFree.
- Trial name
- NCT07079306
- Testing
- BeFree+Bot, BeFree
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- George Washington University
Smoking Cessation
Escape Smoke Project: Non-Intervention Non-Drug Multicenter Study on the Real-life Effectiveness of Smoking Cessation in General Practice in Denmark
Real life smoking cessation rates after 24 weeks non-intervention design. Approximately 40 General Practice (GP) centers with 800 smokers will participate.
- Trial name
- ESCAPE SMOKE (NCT01544621)
- Testing
- Smoking cessation
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- Pfizer
Cigarette Smoking
Culturally Targeted & Individually Tailored Smoking Cessation Study: LGBT Smokers
For the approximately 4.6 million LGBT persons in the U.S., smoking rates among those living in urban areas are roughly twice that of heterosexuals.
- Trial name
- NCT01633567
- Testing
- Culturally Targeted Cessation Program, Non-Targeted Cessation Program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Tobacco Use Cessation, Addiction
An Evaluation of the Tobacco Prevention Toolkit Healthy Futures: Alternative-to-Suspension Vaping Intervention
The Healthy Futures: Alternative-to-Suspension Curriculum is a free, online curriculum developed to educate students and provide them with resources to quit tobacco/nicotine use.
- Trial name
- NCT06483412
- Testing
- Healthy Futures: Alternative-to-Suspension Curriculum
- Where
- United States
- Volunteers
- 2,540 people, healthy volunteers welcome
- Sponsor
- Stanford University
Smoking Cessation
Smoking Reduction and Cessation Interventions for Chinese
This study aims at developing and testing a stage-based scheduled smoking intervention that targets to encourage smokers to reduce smoking and to facilitate smoking abstinence.
- Trial name
- NCT00714532
- Testing
- Expert System Only, Enhanced Expert System
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking
Healthier Hearts and Brains in Treating Smoking: The HABITS Study
80 nicotine dependent adults ages 18-65 who desire to quit smoking will be screened and, if eligible, enrolled and randomized to one of two four-week treatments for smoking cessation.
- Trial name
- HABITS (NCT00581464)
- Testing
- Standard Behavioral Therapy, Mindfulness Based Addiction Therapy
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Smoking Cessation
Comparison of Pharmacokinetic Profiles of 3 New Nicotine Gum Formulations With a Reference Gum
The purpose of the study is to compare the pharmacokinetic (PK) profiles and assess bioequivalence between three new nicotine gum formulations and a reference nicotine gum in healthy smokers.
- Trial name
- NCT02356913
- Testing
- Nicotine gum
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fertin Pharma A/S
Smoking Cessation
Using Technology to Help Low-income and Latino Smokers Quit
The Institute for International Internet Interventions for Health (i4Health) at Palo Alto University proposes to develop digital tools specifically designed to help low income English-speaking and Spanish-speaking smokers to…
- Trial name
- NCT02666482
- Testing
- Stop Smoking SF Web App - baseline
- Where
- United States
- Volunteers
- 1,107 people, healthy volunteers welcome
- Sponsor
- i4Health
Obesity, Overweight
Semaglutide for Post-Smoking Cessation Weight Management
This trial will examine the effect of semaglutide 2.4mg on changes in body weight, body composition, and peripheral and central mechanisms that control appetite, satiety, and food intake in the context of smoking cessation.
- Conditions
- Obesity, Overweight, Cigarette Smoking
- Trial name
- NCT06173778
- Testing
- semaglutide 2.4mg, Nicotine Replacement Therapy (NRT, nicotine patch), Brief Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Carcinoma In Situ, Current Smoker
Implementing a Virtual Tobacco Treatment for Cancer Patients in Community Oncology Practices
This phase II trial studies how well smoking cessation treatment plans work in tobacco-dependent cancer patients when delivered virtually as part of their cancer care in community oncology practices.
- Conditions
- Carcinoma In Situ, Current Smoker, Malignant Neoplasm, Primary Neoplasm
- Trial name
- NCT03808818
- Testing
- Behavioral, Psychological or Informational Intervention, Nicotine Replacement, Quality-of-Life Assessment
- Where
- 42 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Healthy Smokers
Nicotine Patch - Bioequivalence Study
The purpose of this study is to evaluate the bioequivalence of a new transdermal nicotine patch to that of a reference formulation following repeated applications
- Trial name
- NCT02089308
- Testing
- Test treatment : V0116 transdermal patch, Reference treatment : Nicotine transdermal patch
- Where
- France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Medicament
Smoking Cessation
The ESTxENDS Trial- Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cigarette) as an Aid for Smoking Cessation.
Cigarette smoking is the leading cause of preventable death in Switzerland and still more than a quarter of the Swiss population smokes cigarettes.
- Trial name
- ESTxENDS (NCT03589989)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Tobacco Use Disorder
Smoking Cessation Behavioral Treatment Study
The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT).
- Trial name
- NCT03948893
- Testing
- Mindfulness-Oriented Recovery Enhancement (MORE), Cognitive Behavioral Therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cigarette Smoking
Tailored Web and Peer Email Cessation Counseling for College Smokers
The RealU2 is a randomized controlled trial to determine the efficacy of an online health and wellness program for young adults with the addition of individualized peer health coaching.
- Trial name
- RealU (NCT01604525)
- Testing
- Tailored Web, Peer Coaching, Untailored Web
- Volunteers
- 1,699 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cigarette Smoking-Related Carcinoma
EQQUAL-NM for the Promotion of Smoking Cessation in Sexual and Gender Minority Young Adults in New Mexico
This clinical trial assesses the acceptability and efficacy of Empowered, Queer, Quitting, and Living--New Mexico (EQQUAL-NM), a smoking cessation intervention for sexual and gender minority young adults in New Mexico.
- Trial name
- NCT06386432
- Testing
- Smartphone App-delivered Smoking Cessation Intervention, Health Promotion and Education, Biospecimen Collection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center