Clinical trials: Social Cognition in Patients With Schizophrenia
Social Cognition in Patients With Schizophrenia
Treating Social Cognition With Theta Burst Stimulation: a Multicentric Study
The purpose of the study is to test a new treatment of social cognition deficits in patients with schizophrenia or schizoaffective disorder by transcranial magnetic stimulation (theta-burst).
- Trial name
- TBS-COG (NCT02479919)
- Testing
- Magstim® Active TBS
- Where
- 3 sites in France
- Volunteers
- 61 people
- Sponsor
- University Hospital, Caen
Neurologic Disorders, Schizophrenia
Characterization of High-Level Cognitive Impairments in Patients With Neuropsychiatric Disorders
Neuropsychiatric disorders are extremely common, severe, and disabling conditions. In the field of psychiatry, they notably include schizophrenia, mood disorders (depressive and bipolar disorders), autism spectrum or…
- Conditions
- Neurologic Disorders, Schizophrenia, Bipolar Disorder (BD), Depressive Disorder
- Trial name
- COGPSY (NCT07295652)
- Testing
- Cognitive assessment, Brain MRI (optional), Electroencephalography (optional)
- Where
- 3 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Schizophrenia and Disorders With Psychotic Features, Psychotic Episode
Effectiveness of a Mindfulness-based Group Training Addressing Social Cognition in First Episode Psychosis (AGES-Mind)
The current investigation aims to compare two group intervention in patients with a first episode of psychosis, that is, people who have suffered their first psychotic episode within 5 years prior to their inclusion in the study.
- Trial name
- AGES-Mind (NCT03309475)
- Testing
- SocialMIND, Psychoeducational multicomponent intervention, Psychosocial treatment
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Schizophrenia Spectrum Disorders, Social Cognition
Using Illusions to Boost Social Cognition
This study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders.
- Trial name
- SOLLUSIONS (NCT07602712)
- Testing
- Visual-illusion social cognition session (immediate), Visual-illusion social cognition session (delayed)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hôpital le Vinatier
Schizophrenia, Social Cognition
Social Dysfunction and Brain Dysfunction in Patients With Schizophrenia
There were a few studies about the relationship of structural or functional abnormalities of brain and social cognitive dysfunctions in patients with schizophrenia.
- Trial name
- NCT01903915
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
SCHIZOPHRENIA 1 (Disorder)
The Effect of ACT-Based Nursing Interventions on Social Cognition, Emotion Regulation and Psychological Flexibility in Patients With Schizophrenia
This randomized controlled trial aims to evaluate the effect of Acceptance and Commitment Therapy (ACT)-based nursing interventions on social cognition, emotion regulation, and psychological flexibility in individuals diagnosed…
- Trial name
- NCT07661225
- Testing
- Acceptance and Commitment Therapy (ACT)-Based Nursing Intervention
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Schizophrenia, Schizo Affective Disorder
Efficacy Study of a New Individualized Rehabilitation Programme for Social Cognition in Patients With Schizophrenia
Patients affected by schizophrenia often present significant deficits in various aspects of social cognition, such as social perception, recognition of one's own and other people's emotional state and the theory of mind.
- Trial name
- SoCIAL (NCT05130853)
- Testing
- Social Skills and Neurocognitive Individualized Training (SoCIAL), Treatmment-as-usual
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- University of Campania Luigi Vanvitelli
Schizophrenia, Quality of Life
Milestones of Adjustment Post-Psychosis
This nested design clinical outcome study of psychiatric case manager education on disease state, psychopharmacology of schizophrenia, relapse, motivational interviewing, and the process of psychological adjustment post-psychosis…
- Conditions
- Schizophrenia, Quality of Life, Adjustment, Psychological, Medication Adherence
- Trial name
- MAPP (NCT01192594)
- Testing
- Training in all modules including MAPP Recovery Model, Training in all modules except MAPP Recovery Model
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia, Cognition Disorders
The Effect of Nicotine on Arousal, Cognition and Social Cognition in Schizophrenic Patients
This study in patients with stable schizophrenia will investigate the effect of nicotine on arousal, cognitive task and social cognition after acute dose administration.
- Trial name
- NCT01186471
- Testing
- A643 (nicotine)
- Volunteers
- 32 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Schizophrenia
Efficacy of Cognitive Remediation in Patients With Schizophrenia or Schizoaffective Disorder Stabilized on Lurasidone
The investigators hypothesize that cognitive remediation will be superior to the active control group on the change from baseline to study end point of cognitive remediation phase on both co-primary outcome measures (standardized…
- Trial name
- NCT01173874
- Testing
- Cognitive Remediation
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- New York State Psychiatric Institute
Women With Recent Diagnosis of Schizophrenia, Men With Recent Diagnosis of Schizophrenia
Gender Differences in Social Cognition in Patients With Schizophrenia of Recent Diagnosis and Healthy Controls Subjects
Individuals with schizophrenia have important and persistent deficits in multiple neurocognitive domains as well as in the Social Cognition (SC).
- Conditions
- Women With Recent Diagnosis of Schizophrenia, Men With Recent Diagnosis of Schizophrenia, Healthy Women, Healthy Men
- Trial name
- NCT02575209
- Testing
- GENDER
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Schizophrenia Disorders, Treatment Resistant Hallucinations
Cognitive and Metacognitive Evaluation in VR-Based Avatar Therapy for Psychosis
This study aims to evaluate the relationship between cognitive, metacognitive and social cognition variables in patients with psychosis undergoing VR-based Avatar Therapy for the treatment of auditory hallucinations.
- Trial name
- Meta-VR-AVATAR (NCT07091344)
- Testing
- VR-Based Avatar Therapy with Cognitive and Metacognitive Assessments
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Sant Joan de Déu
Schizophrenia, Schizoaffective Disorder
The Efficacy of Metacognitive Skills Training in the Context of Forensic Psychiatric Care
Deficiencies in social cognition are part of the core symptomatology of psychotic disorders. And deficiencies in social cognition, the closely related concept of metacognition, and, for example, paranoid attitudes are all…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Psychotic Disorders, Delusional Disorder
- Trial name
- NCT06005766
- Testing
- Metacognitive Skills Training (MCT), Treatment as usual
- Where
- Finland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Schizophrenia, Oxytocin
Adult Oxytocin Study
In this study, investigators will examine the behavioral effects and neurophysiological mechanisms of the pro-social neuropeptide oxytocin in patients with recent-onset schizophrenia.
- Conditions
- Schizophrenia, Oxytocin, Social Cognition
- Trial name
- OT (NCT02577575)
- Testing
- Oxytocin, Saline Nasal Spray
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Gambling
Effectiveness of Exergames on Cognitive, Social Functionamong Chronic Schizophrenia
An experimental study with random assignment will be adopted. The participants from 2 hospitals will be assigned to two groups: experimental group (n=77), and control group (n=77).
- Trial name
- exergames (NCT05933356)
- Testing
- playing exergames, scheduled activities
- Where
- Taiwan
- Volunteers
- 154 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Social Cognition in Patients With Schizophrenia
Treating Social Cognition With Theta Burst Stimulation; a Pilot Sudy
The purpose of the study is to test a new treatment of social cognition deficits in patients with schizophrenia or schizoaffective disorder by transcranial magnetic stimulation (theta-burst).
- Trial name
- PilotTMS-COG (NCT02440867)
- Testing
- Active TBS
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Schizophrenia, Schizoaffecitve Disorder
Digital Therapeutics for Social Cognitive Function in Schizophrenia Spectrum Disorder
The purpose of this study is to evaluate the safety and preliminary effectiveness of a smartphone-based digital therapeutic application (AffectUs) for improving social cognition, particularly emotion processing and social cue…
- Trial name
- NCT07755605
- Testing
- Digital therapeutic (AffectUs), Psychoeducational materials
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Schizophrenia, Oxytocin
Oxytocin MEG Study
The specific aim of this proposal is to investigate the neurophysiological mechanisms of oxytocin's (OT) prosocial effects in patients with schizophrenia and healthy subjects using magnetoencephalography.
- Conditions
- Schizophrenia, Oxytocin, Magnetoencephalography (MEG), Social Cognition
- Trial name
- MEG (NCT02568709)
- Testing
- Oxytocin, Saline Nasal Spray
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Indication for Modification of Patient Cognitive Status
Efficacy of Repyflec Cognitive Remediation Group Training in Schizophrenia
The purpose of this study was to develop an integrative intervention for schizophrenia taking into account previous efficacious therapies.
- Trial name
- NCT01279070
- Testing
- Repyflec cognitive remediation training
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Fundació Sant Joan de Déu