Clinical trials: Sodium Intake
Healthy
Effects of Sodium Intake on (PK/PD) Relationship of a Single Dose of a Renin Angiotensin System-Blocker
The impact of sodium intake on plasma drug concentrations has previously been reported in the literature for verapamil and quinidine but, to the investigators' knowledge, never with renin-angiotensin system blockers such as AT1R…
- Trial name
- NCT00310778
- Testing
- high sodium diet, low sodium diet, ramipril 10 mg
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension
Phosphate in Blood Pressure Regulation
High dietary phosphate intake in the general population is associated with a higher risk for developing kidney disease and cardiovascular disease with an increased overall mortality.
- Trial name
- Phos-RR (NCT02822131)
- Testing
- sodium phosphate, sevelamer, sodium bicarbonate, sodium chloride
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hypertension, Overweight or Obesity
Education to Decrease in Sodium Intake Evaluated With 24 Hour Urinary Sodium Excretion (RCT)
WHO identifies as an important risk factor and potentially modifiable to high sodium intake (>2g/day 5g salt/day). Also, an insufficient consumption of potassium ( 3.5 g/day).Therefore, the results of this research could be the…
- Conditions
- Hypertension, Overweight or Obesity, Diabetes Mellitus, Type 2
- Trial name
- RCT (NCT04894344)
- Testing
- Education group
- Where
- Mexico
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Health, Appetite Regulation
Sodium Alginate in Chocolate Milk, Satiety and Glycemic Control
This study compares the effects of isovolumetric (325 ml) preloads of chocolate milk supplemented with sodium alginates at incremental doses on inter-meal glucose levels, appetite scores and food intake in healthy adult men.
- Conditions
- Health, Appetite Regulation, Glucose Metabolism
- Trial name
- NCT01877460
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Sodium Excess, Cardiovascular Risk Factor
A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk Factor
This study will evaluate the effect of a short, animated storytelling intervention video on sodium intake as a major risk factor for cardiovascular disease on immediate and medium-term retention of knowledge about the risks of…
- Conditions
- Sodium Excess, Cardiovascular Risk Factor, Education Entertainment Intervention, Short, Animated Storytelling
- Trial name
- NCT05735457
- Testing
- A short, animated storytelling video on dietary sodium
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Behavior, Eating
Menu to Meal (M2M) Menu Labeling Intervention Study
This study evaluates the impact of culturally tailored menu labeling interventions on psychosocial factors and ordering behavior among customers in two independently owned Hispanic restaurants in East-Central Texas.
- Trial name
- NCT07329452
- Testing
- Paper menu, Digital menu condition
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Salty Taste, Spicy Diet
Spicy Diet on Salty Taste and Salt Intake
Excess dietary salt intake is closely associated with the development of hypertension and cardiocerebral vascular diseases. Reduction in high salt intake significantly prevents hypertension and cardiocerebral events.
- Trial name
- NCT01982669
- Testing
- No Intervention
- Where
- China
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Zhiming Zhu
Healthy Adult, Alcohol Abstinence
Evaluation of Sodium Excretion and Dietary Intake Via a New Sodium Food Frequency Questionnaire
DETERMINATION OF URINARY SODIUM EXCRETION AND DIETARY SODIUM INTAKE IN ADULTS BY DEVELOPING A FOOD FREQUENCY QUESTIONNAIRE FOR ADDED-SALT FOODS Dear Participant, A doctoral thesis study titled "Determination of Urinary Sodium…
- Conditions
- Healthy Adult, Alcohol Abstinence, Tobacco Abstinence
- Trial name
- NCT07717645
- Testing
- Dietary Assessment (BTS-Salt), Urinary Analysis (Gold Standard vs. Practical), Nutritional Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Toros University
Cardiovascular Risk Factor
The Salty Gut: Effects of High Dietary Salt Intake on the Gut Microbiota
Gut microbiota has a role in cardiovascular disease and recent findings in rodents show dietary salt can negatively alter gut microbiota composition. High salt intake is a risk factor for cardiovascular disease.
- Trial name
- NCT04229680
- Testing
- High Salt, Recommended Salt
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Healthy Volunteer
A School-based Education Programme to Reduce Salt Intake in Children and Their Families
The study is to test whether an education programme targeted at school children can lower salt intake in children and their families.
- Trial name
- School-EduSalt (NCT01821144)
- Testing
- Salt reduction, Control
- Where
- China
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Dietary Sources of Sodium Intake
Salt Sources Study
The Centers for Disease Control and Prevention conducted an observational cross-sectional study to obtain information about the amount of sodium consumed from various sources (including sodium from processed and restaurant foods…
- Trial name
- NCT02474693
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Mary Cogswell
Healthy
Sodium vs Potassium Education to Improve Vascular Health
The goal of this clinical trial is to determine if a self-selected high potassium diet is easier to achieve and more effective at improving vascular health than a low sodium diet in generally healthy young adults who typically…
- Trial name
- NCT07221448
- Testing
- High potassium dietary education/counseling, Low sodium dietary education/counseling
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Florida State University
Hyperaldosteronism, Hypertension
Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood Pressure
Some patients with high blood pressure can experience an increase of blood pressure by 10 percent or more by taking in salt. These patients are referred to as having "salt-sensitive" (SS) hypertension.
- Trial name
- NCT00001176
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Edema, Perioperative/Postoperative Complications
Body Composition and Serum Biochemistry After Intravenous Infusion or Oral Intake of Saline in Healthy Volunteers
The investigators conducted a cross-over study to compare the response of healthy young volunteers to a rapid oral intake or intravenous infusion of 0.9% saline solution on the body composition, serum electrolytes, albumin, and…
- Trial name
- NCT01539798
- Testing
- Oral saline, Intravenous saline
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Elevated Blood Pressure, Vascular Health
Sodium-rich COndiments Unifying Health and Taste
This research aims to develop an evidence-based classification for sodium-rich condiments (natremic index) based on their CVD-related risks.
- Conditions
- Elevated Blood Pressure, Vascular Health, Sensory Evaluation
- Trial name
- Scout (NCT07397754)
- Testing
- Control porridge with no condiments, Porridge with light soya sauce, Porridge with fermented bean paste
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Maintenance of Recommended Sodium Intake
Maintenance of Recommended Sodium Intake
The overall objective of this study is to assist the general public in achieving and maintaining the currently recommended sodium intake of 1500 mg/day through a reduced sodium intervention that emphasizes spices and herbs.
- Trial name
- SPICE (NCT01615159)
- Testing
- Behavior and lifestyle counseling
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Bone Metabolism, Electrolyte Metabolism
Salty Life 7 Study: Effect of High Salt Intake on Several Physiological Systems in Immobilisation
The Salty Life 7 study aimed to examine the effect of a high salt (sodium chloride, NaCl) intake on different forms of sodium retention, acid-base balance and bone metabolism and other influenced physiological systems.
- Conditions
- Bone Metabolism, Electrolyte Metabolism, Acid-Base Metabolism, Energy Metabolism
- Trial name
- SL7 (NCT01183299)
- Testing
- Dietary salt intake
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Postural Tachycardia Syndrome (POTS)
Effect of Dietary Sodium Intake on Vascular Endothelium
The investigators will test the hypothesis that markers of vascular endothelial dysfunction will be exaggerated acutely with an extreme high sodium diet compared to an extreme low-sodium diet.
- Trial name
- NCT01550315
- Testing
- Pulsitile Arterial Tonometry (PAT) Protocol, Calf Blood Flow in Reactive Hyperemia (CBF-RH), Evaluation of Forearm-Mediated Dilation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Healthy Humans
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Healthy Humans.
The aim of the study is to test the hypothesis that the function and/or regulation of aquaporin 2 and/or endothelial sodium channels in the principal cells of healthy humans is abnormal at high and low sodium intake
- Trial name
- NCT00345215
- Testing
- High Sodium Diet, Low Sodium Diet
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Multiple Sclerosis
The Effect of Dietary Salt Intake on Immune Function in Patients With Multiple Sclerosis
The purpose of this work is to investigate the influence of dietary salt intake on immune function in multiple sclerosis (MS) subjects and healthy controls.
- Trial name
- NCT02282878
- Testing
- High/Low Sodium Diet
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Yale University