Clinical trials: Sodium Intake
Osteoporosis
Effect of Sodium Intake on Calcium Retention in Girls
Optimal calcium retention is important for building bone mass within the genetic potential, a key to reducing risk of osteoporosis later in life. Calcium retention is high during the rapid growth period.
- Trial name
- NCT01564238
- Testing
- Low Na diet (1.3 g/d), High sodium diet (3.8 g/d)
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Purdue University
Healthy Subjects
The Effect of Atorvastatin on Renal Function in Healthy Subjects During Normal and High Sodium Intake
We wanted to test the hypothesis that acute treatment with atorvastatin changes renal sodium handling, renal hemodynamics, tubular function and vasoactive hormones in healthy humans during normal and high sodium intake.
- Trial name
- NCT00678184
- Testing
- Atorvastatin
- Where
- 2 sites in Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Dietary Deficiency, Sodium
Cross-sectional, Non-randomized Observational Study to Assess the Frequency of Reduced Sodium Intake in the Primary Care Setting - LAXAP
This study is a cross-sectional epidemiological, observational study. It would be carried out in primary health care sites. The purpose of this study is estimating the percentage of patients aged 60 years or older who suffer from…
- Trial name
- LAXAP (NCT06121583)
- Where
- 14 sites in Spain
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- Casen Recordati S.L.
Hypertension, Living Kidney Donor
Dietary Sodium Intake and Blood Pressure in Living Kidney Donors
This is a pilot study to determine the feasibility of the study design and examine the main outcome whether low dietary sodium intake is superior to high dietary sodium intake in controlling blood pressure to be within the…
- Conditions
- Hypertension, Living Kidney Donor, Dietary Sodium Intake
- Trial name
- SPLID (NCT05041829)
- Testing
- Dietary sodium
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Sodium Excess, Hypertension
Effects of a Six-Day Whole-Diet Intervention on Taste Perception and Dietary Behaviour in Young Adults
This study aims to investigate the effects of a specific diet modification on the pleasantness, desire, and saltiness intensities of selected foods and an ad libitum breakfast buffet through a randomized controlled trial with…
- Conditions
- Sodium Excess, Hypertension, Salty Taste
- Trial name
- NCT07726394
- Testing
- Experimental: Increased Salty Food Intake, Experimental: Decrease Salty Food Intake, Active Comparator: Maintain Usual Diet
- Where
- Malaysia
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Sunway University
Hypertension
Urine Chloride/Creatinine Ratio for Estimation of Urine Sodium
We plan to assess the accuracy of a new means of estimating urine sodium excretion. We will compare the chloride to creatinine ratio obtained by titrator sticks with urine sodium measured by a standard laboratory.
- Trial name
- NCT00324883
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Hypertension
Effect of High- and Low-sodium Intake on the Pharmacokinetics and Pharmacodynamic Effects of Fimasartan
It has been known that the blood pressure lowering effect of angiotensin receptor antagonists (ARBs) and angiotensin converting enzyme (ACE) inhibitors is impaired in patients on high sodium intake.
- Trial name
- NCT02147704
- Testing
- High-sodium diet, low-sodium diet
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- DongGuk University
Healthy Nutrition, Culinary Medicine
Increasing Vegetable Intake Using Monosodium Glutamate: A Reduced-Effort Intervention
Food Intake Study: This will be a 4-week randomized controlled intervention study with a vegetable intake questionnaire, daily food intake, and seasoning usage measurement to test the acceptability of different seasoning…
- Conditions
- Healthy Nutrition, Culinary Medicine, Sodium Excess
- Trial name
- NCT05591612
- Testing
- Salt replacement seasoning (50% salt and 50% MSG) mix, Salt replacement seasoning (70% salt and 30% MSG) mix, NaCl (sodium chloride/table salt)
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Polycystic Kidney, Autosomal Dominant
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease
The aim of the study is to test the following hypotheses: 1. that the function and/or regulation of AQP2 and /or ENaC in the principal cells is abnormal in autosomal dominant polycystic kidney disease. 2.
- Trial name
- NCT00410007
- Testing
- High Sodium Diet, Low Sodium Diet, Hypertonic saline infusion
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Carolina Cannillo
Th17 Helper Immune Cells, Autoimmunity
Salt and TH-17 in Healthy Human Subjects
The overall goal of this study is to evaluate the association between sodium and TH17 cells in human subjects. The subjects will have levels of TH-17 and various hormones measured on low salt diet, low salt diet with intravenous…
- Conditions
- Th17 Helper Immune Cells, Autoimmunity, Salt Intake, Sodium Chloride
- Trial name
- NCT02261688
- Testing
- Low salt diet, Low salt diet + IV normal saline, Liberal salt diet
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
The Effects of Sodium Bicarbonate Supplementation on Endurance Performance in Recreational Female Runners
Sodium Bicarbonate Intake on Endurance Performance
Sodium bicarbonate (SB) is one of the ergogenic aids that enhance short-duration, high-intensity sports performance by improving the buffering system.
- Trial name
- NCT06826222
- Testing
- Sodium Bicarbonate (NaHCO3), Sodium Chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Essential Hypertension and Healthy Controls
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Essential Hypertension
The aim of the study is to test the following hypotheses: that the function and/or regulation of AQP2 and/or ENaC in the principal cells is abnormal in essential hypertension.
- Trial name
- NCT00345124
- Testing
- high sodium diet, Low Sodium Diet
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Sodium Intake, General Population
Research for the Improvement in Measurement Methods and the Effect of Sodium Intake on Cardiovascular Health
Epidemiological, clinical and animal-experimental evidence shows a direct relationship between dietary sodium intake, blood pressure and cardiovascular event.
- Trial name
- NCT01438619
- Where
- South Korea
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- DongGuk University
Obesity and Overweight
Reduction in Consumption of Sweetened Beverages on Weight, Body Composition and Blood Pressure in Young Adults
The impact of reduction in consumption of caloric and no caloric sweetened beverages on: weight body composition blood pressure young adults
- Trial name
- NCT02347267
- Testing
- Caloric and non-caloric SSBS reduction, Caloric SSBS reduction
- Where
- Mexico
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Atopic Dermatitis (Eczema), Psoriasis
The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease
The goal of this clinical trial is to demonstrate the feasibility of a trial that examines the impact of changes in dietary sodium intake on skin sodium levels, atopic dermatitis, and psoriasis.
- Trial name
- SIS-ISD (NCT07487831)
- Testing
- Sodium chloride tablets
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dietary Sources of Sodium, Population Sodium Intake
Evaluating Implementation and Scale-Up of Nigeria's National Sodium Reduction Program
The NaSS aims to assess the extent to which the SHAKE program is implemented within Nigeria by the Nigerian Agency for Food and Drug Administration and Control (NAFDAC) using a type III hybrid, mixed method study design.
- Trial name
- NaSS (NCT04765865)
- Testing
- SHAKE Package
- Where
- 3 sites in Nigeria
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hypertension
Vascular Responses to Sympathetic Activation and Altered Shear Rate: The Impact of Hypertension and Sodium Intake
The aim of this study is to determine if alterations in sodium intake alter peripheral vascular function and exercise tolerance in young individuals.
- Trial name
- NCT03558022
- Testing
- Salt Pills
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Hypertension, Physical Disability
The Effect of Sodium Reduction on Blood Pressure and Physical Function in Older Adults
This study will examine the effects of low sodium meal plan on seated blood pressure in older adults from a community-based, congregate senior living facility.
- Conditions
- Hypertension, Physical Disability, Aging
- Trial name
- SOTRUE (NCT04074941)
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Obesity, Hypertension
Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans
Experimental data have shown that timing of sodium intake impacts diurnal patterns of sodium excretion. The purpose of this study is to test the hypothesis that the time of day for salt intake impacts (1) blood pressure rhythms…
- Conditions
- Obesity, Hypertension, Circadian Dysregulation, Salt; Excess
- Trial name
- NCT04021355
- Testing
- Oral sodium supplementation
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy Volunteers, Probiotics
Salt Intake and Lactobacillus Abundance
To investigate the influence of an increased salt intake (6 g/d for 14 days) on the relative abundance of gut lactobillus species in healthy men
- Conditions
- Healthy Volunteers, Probiotics, Sodium
- Trial name
- NCT02971787
- Testing
- Probiotics, Salt
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany