Clinical trials: Sodium Intake
Hypertension
Human Sodium Balance Study
The overall objective of this study is to examine how dietary sodium is used by the body. In a racially diverse sample of adults, the investigators will examine the effects of high and low dietary sodium intake on the storage and…
- Trial name
- MEASURE (NCT04110262)
- Testing
- High dietary sodium intake, Low dietary sodium intake
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, San Diego
Diabetes Mellitus
Fiber-Enriched, Sodium-Controlled Enteral Formula for Glycemia and Blood Pressure in Tube-Fed Residents With Diabetes
This study aims to evaluate the effects of a fiber-enriched, sodium-controlled enteral nutrition formula on glycemia, blood pressure, and nutritional status in long-term care residents with diabetes receiving tube feeding.
- Trial name
- FIBER-BP-DM (NCT07504380)
- Testing
- Fiber-Enriched, Sodium-Controlled Enteral Formula
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Taipei Medical University
Sodium Intake, Arterial Stiffness
Effects of Sodium Intake on Arterial Stiffness in Black Men and Women
The purpose of this study is to explore the influence of sodium intake on arterial stiffness in African American/Black adults.
- Trial name
- NCT05815043
- Testing
- Low-sodium intake, High-sodium intake
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Texas State University
Bipolar Affective Disorder
Effect of Regulated Add -on Sodium Chloride Intake on Stabilization of Serum Lithium Concentration in Bipolar Disorder
Bipolar affective disorder or manic -depressive psychosis (MDP) is a mood disorder affecting 2.4% of the global population . Lithium is considered as the "gold standard" for the treatment of bipolar disorder but the clinical use…
- Trial name
- NCT04222816
- Testing
- Lithium Carbonate, Sodium chloride
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Diet, Sodium-Restricted, Heart Failure, Systolic
Effect of Sodium Intake on Brain Natriuretic Peptide Levels in Patients With Heart Failure
The SODA-HF trial is a randomized, double-blind, controlled trial to evaluate the effect of moderate to severe sodium restriction on brain natriuretic peptide in patients with heart failure and reduced ejection fraction (less…
- Conditions
- Diet, Sodium-Restricted, Heart Failure, Systolic, Natriuretic Peptide, Brain, Clinical Trial
- Trial name
- SODA-HF (NCT03351283)
- Testing
- Severe sodium restriction, Moderate sodium restriction
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Instituto Mexicano del Seguro Social
High Blood Pressure
Salt and Gut Study
High sodium intake is a significant risk factor for hypertension. Recently, animal studies connect high sodium intake to the gut-immune axis and highlight the gut microbiome as a potential therapeutic target to counteract…
- Trial name
- NCT04958148
- Testing
- Salt pills
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Augusta University
Heart Failure
Dietary Sodium Intake and Outcomes in Heart Failure
Currently, the recommendations for sodium intake restriction for patients with heart failure are mostly based on expert consensus and observational evidence, whereas smaller randomized studies have actually suggested that strict…
- Trial name
- PROHIBITSodium (NCT02467296)
- Testing
- Dietary plan with controlled amount of Sodium
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Stony Brook University
Heart Failure, Systolic, Sodium Imbalance
Low-salt Bread in Heart Failure, Pilot Study
SUMMARY Rationale Patients with heart failure may suffer from a poor quality of life (QoL) due to frequent hospital admittance, medication intake, and symptoms as a result of progression of their disease.
- Conditions
- Heart Failure, Systolic, Sodium Imbalance, Food Selection
- Trial name
- NCT05589428
- Testing
- Low sodium bread
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- VieCuri Medical Centre
Healthy
Effects of Divalproex Sodium on Food Intake, Energy Expenditure, and Posture Allocation
The purpose of the proposed study is to identify the mechanisms responsible for the weight gain associated with Depakote treatment, and to identify methods to prevent and treat weight gain in people taking Depakote.
- Trial name
- VPA (NCT00287053)
- Testing
- divalproex sodium
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Type 2 Diabetes
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes
SGLT2 inhibitors have demonstrated to mitigate cardiorenal risk in people with type 2 diabetes and are likely to play an increasingly large role in the treatment of patients with diabetes, chronic kidney disease and hypertension.
- Trial name
- DESIGN (NCT06983054)
- Testing
- ertugliflozine, low salt diet, high salt diet
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 34 people
- Sponsor
- Amsterdam UMC, location VUmc
Healthy
Dietary Salt Intake and Vascular Function
The purpose of this study is to look at the effects of high- and low-salt diets on blood vessel function in healthy subjects.
- Trial name
- NCT00590512
- Testing
- High sodium, Low sodium
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Healthy Older Adults
Interactive Effects of Sodium and Potassium on Vascular Health in Older Adults
The goal of this clinical trial is to determine if a high potassium intake can counteract the harmful effects of excess sodium on endothelial function in older adults with no history of cardiometabolic disease.
- Trial name
- NCT07649005
- Testing
- low sodium/low potassium diet, high sodium/low potassium diet, high sodium/high potassium diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Arterial Hypertension
Effect of Dietary Sodium Intake on Blood Pressure in Hypertensive Patients in Primary Care
There is strong evidence that our current consumption of salt is the major factor increasing blood pressure (BP). The current salt intake in most countries in the world is 9 to 12 grams per day (g/d), whil the World Health…
- Trial name
- NCT01334138
- Testing
- A 4-week diet, low in sodium.
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Ghent
Dietary Habits, Risk Factor, Cardiovascular
Sodium Intake in Ecuadorian Population
This study is aim to determine the sodium intake in Ecuadorian population that is an unknown information at present. For that, 24h urine samples will be collected from 130 subjects working either at tue USFQ or HDLV to measure…
- Conditions
- Dietary Habits, Risk Factor, Cardiovascular, Nutritional Disorder
- Trial name
- NCT03154502
- Testing
- Urinary sodium excretion
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad San Francisco de Quito
Hypertension
Genetic Determinant of Blood Pressure Sensitivity to Salt Intake
Nedd4.2 is a regulator of ENac, a transporter of sodium involved in the regulation of salt retention by the kidney. The study address the consequence of a frequent genetic variation leading expected to impact the function of…
- Trial name
- JEU004 (NCT01706887)
- Testing
- Diet Amiloride
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension
Comparison on Blood Pressure Effect of an Equivalent Sodium Intake, With Different Nature, for Hypertensive Subjects
Numerous large-scale epidemiological studies have made it possible to establish a link between the average consumption of table salt (sodium chloride) and blood pressure figures.
- Trial name
- SODIVASC-II (NCT05108402)
- Testing
- Phenotyping, Drug intake
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Clermont-Ferrand
Blood Pressure, Hypertension
Clarifying Optimal Sodium Intake Project
Hypertension is a leading risk factor for cardiovascular disease (CVD) globally, accounting for 25-35% of the population-attributable fraction.
- Conditions
- Blood Pressure, Hypertension, Kidney Disease, Cardiovascular Disease
- Trial name
- COSIP-1 (NCT02738736)
- Testing
- Sodium Reduction
- Where
- Ireland
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- University College Hospital Galway
Health Behaviour
Can Primary Care Change Elderly Physical Activity and Salt Intake? An Australian Pilot Trial
A randomised controlled trial to test if offering three visits to a dietician + two visits to a physiotherapist over six months + a home sphygmomanometer, will result in a reduction in sodium intake and an increase in fitness in…
- Trial name
- ECOBEING (NCT01693536)
- Testing
- Lifestyle counselling
- Where
- Australia
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Health HQ
Hypertension
Influence of Sodium Intake on Left Ventricular-arterial Coupling
The objective of the present study is to asses the effectiveness of the aorta-ventricular coupling according to low and high sodium intake in 28 controled hypertensive patients.
- Trial name
- NCT01965236
- Testing
- sodium chloride
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Montpellier