Clinical trials: Soft Tissue
Broken Teeth
Soft Tissue Outcomes Of Badly Broken-Down Teeth Treated With Orthodontic Extrusion Compared With Immediate Implant Placement
Many patients suffer from tooth substance loss as a result of fracture or decay of teeth situated in the esthetic zone. This might commonly occur with car accidents, sport injuries, falls or even fistfights.
- Trial name
- NCT04436094
- Testing
- Orthodontic extrusion, Immediate implant placement
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alcoholism, HIV Infection
Genetic Factors and Interrelationships for Sexual Orientation, Susceptibility to HIV and Kaposi's Sarcoma, Alcoholism and Psychological Traits, and Histocompatibility Antigens
We propose to test, by DNA linkage analysis of family pedigree members, the following interrelated hypotheses: 1) that sexual orientation is genetically influenced; 2) that the development of Kaposi's sarcoma and other outcomes…
- Conditions
- Alcoholism, HIV Infection, Homosexuality, Kaposi's Sarcoma
- Trial name
- NCT00001294
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Leiomyosarcoma
The Role of Pre-Surgical Tru - Cut Biopsy in the Management of Atypical Myometrial Lesions
The Tru-cut biopsy (TCB) for targeting pelvic tumors is well established in gynecologic oncology. However, its reliability for differentiating of uterine sarcoma in "myoma-like" uterine lesions has been confirmed by only a few…
- Trial name
- MYSTR (NCT06521060)
- Testing
- tru cut biopsy
- Where
- Czechia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Dupuytren's Contracture
Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures
The primary objective of this study is to assess the safety of two concurrent injections of AA4500 into the same hand in subjects with multiple Dupuytren's contractures with palpable cords followed 24 to 72 hours later by a…
- Trial name
- NCT01674634
- Testing
- XIAFLEX / XIAPEX
- Where
- 25 sites in United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
to Study Soft Tissue Health and Stability
A 3-YEAR CLINICAL INVESTIGATION ON THE NOBEL ACTIVE® TIULTRA™ IMPLANT AND ON1™ BASE XEAL1™ _____________________________________________________________
Soft tissue thickness, using IOS, between implant insertion (baseline) and 3-year follow-up has no changes
- Trial name
- NCT04383834
- Testing
- NobelActive® TiUltra™ implants and On1™ Base/Xeal™ along with On1 components
- Where
- Italy
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Giacomo Fabbri
Metrorrhagia, Pelvic Pain
Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)
In this project, the proposition is that the use of daily dosed Myfembree ( a combination of relugolix with estradiol and norethindrone acetate), FDA-approved medication to treat heavy menses fibroid-related symptoms, has the…
- Conditions
- Metrorrhagia, Pelvic Pain, Menorrhagia, Leiomyoma
- Trial name
- SOUL (NCT05538689)
- Testing
- Myfembree Oral Product
- Where
- 6 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Healing Surgical Wounds, Pain
L-PRF vs PBM on Extraction Socket Healing
The aim of this study is to compare leukocyte and platelet-rich fibrin (L-PRF) and photobiomodulation (PBM) applications, which have been repeatedly reported to be superior to control groups, in terms of pain, soft tissue and…
- Trial name
- NCT06328413
- Testing
- photobiomodulation, Leukocyte and Platelet Rich Fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Controlling Mild to Moderate Bleeding During Surgery
The EVARREST® Pediatric Mild or Moderate Liver and Soft Tissue Bleeding Study
The objective of this study is to evaluate the safety and hemostatic effectiveness of EVARREST as an adjunct to controlling mild to moderate soft hepatic parenchyma or soft tissue bleeding during open hepatic, abdominal, pelvic…
- Trial name
- NCT03255174
- Testing
- EVARREST® Fibrin Sealant Patch
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ethicon, Inc.
Gingival Recession
Assessment of The Accuracy of Complete Crown 3D Superimposition Technique Relative to The Gold Standard Technique for Digital Quantification of Volumetric Soft Tissue Changes in The Esthetic Zone
The aim of this study is to assess the precision of the complete crown technique employed for the superimposition of 3D models, specifically in the quantitative volumetric evaluation of gingival tissues.
- Trial name
- NCT06457672
- Testing
- Group I, Group II
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Horizontal Ridge Deficiency
Alveolar Ridge Augmentation Following Self-Inflating Soft Tissue Expander
The objective of this study will be to assess and compare between sub-periosteal self- inflating osmotic tissue expanders used as preparatory surgery before alveolar ridge augmentation and periosteal releasing incision using…
- Trial name
- NCT03153995
- Testing
- soft tissue expansion
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontitis, Periodontal Diseases
Influence of Flap Position Following FibReORS
There is lack of data in literature on keratinized tissue increase after FibReORS in relation to primary flap position. This study has been designed as a split-mouth randomized trial to assess the influence of flap position after…
- Trial name
- NCT05140681
- Testing
- FibReORS with apically positioned flap (apical position), FibReORS with apically positioned flap (crestal position)
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Heart Failure, Liver Fibrosis
Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues
Magnetic resonance elastography is a novel non-invasive MRI technique to obtain stiffness of soft tissues such as liver, heart, kidneys, etc.
- Conditions
- Heart Failure, Liver Fibrosis, Cardiac Transplant Rejection, Aortic Aneurysms
- Trial name
- MRE (NCT01757730)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Arunark Kolipaka
Adenomyosis, Uterine Leiomyoma
The Association Between Adenomyosis/Uterine Myoma and Lower Urinary Tract Symptoms
The aim of this study is to assess the relationship between adenomyosis/myoma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.
- Trial name
- NCT02495311
- Testing
- myomectomy or adenomyomectomy
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Plantar Fasciitis of Both Feet
Customized Shoe-padding Orthotics for Plantar Fasciitis
While human body receives large external force or motions, minor injuries to the soft tissues will be produced and will lead to acute or chronic inflammation reactions.
- Trial name
- NCT03226288
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Postural; Defect
Comparison of Instrument Assisted Soft Tissue Mobilization and Myofascial Gun in Upper Cross Syndrome
To compare the effects of Instrument Assisted Soft Tissue Mobilization and Myofascial gun in Upper Cross Syndrome
- Trial name
- NCT05474443
- Testing
- Myofascial gun with conventional therapy, Instrument Assisted Soft Tissue Mobilization with Conventional therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Haemodialysis Complication
Sodium Deposition in Soft Tissues of Patients with Kidney Disease
Sodium (Na+) hemostasis is abnormal in CKD patients, and this element can be deposited in the skin, muscle, and skeleton - to cope with long term sodium loading.
- Trial name
- NCT03004547
- Testing
- Measuring sodium content
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chris McIntyre
Gum Disease
Influence of Implant Crown Transmucosal Contour Design on Soft and Hard Tissue Clinical Outcomes
This study will evaluate how the crown's shape under the gums will influence the gum tissue around dental implants.
- Trial name
- NCT06185075
- Testing
- Implant crown delivery
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Site Preservation, Soft Tissue Healing
Site Preservation Was Performed Through an Open Healing Oral Restorative Membrane
In this study, an open healing oral restoration membrane was used for site preservation in the esthetic area after tooth extraction to maintain the space for tooth extraction and bone formation.
- Conditions
- Site Preservation, Soft Tissue Healing, Anterior Dental Aesthetic Area
- Trial name
- NCT07334067
- Testing
- site preservation surgery with open healing, site preservation surgery with close sutures
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Peri-implant Bone Loss, Implant Stability
Comparison Between Two Different Tissue-Level Implant Systems: A Prospective Clinical Study
The objective of this prospective study is to compare clinically and radiographically two different tissue-level implants, in partially edentulous patients in the posterior area of the maxilla and mandible.
- Conditions
- Peri-implant Bone Loss, Implant Stability, Vertical Soft Tissue Thickness
- Trial name
- NCT04761445
- Testing
- Straumann Standard Plus implant and JDental care (JD) Octa implant
- Where
- Lebanon
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Edentulous Alveolar Ridge
Long-term Follow up of Mucosal Tissue Height Influence on Peri-implant Bone Levels.
Our study looks into how the thickness of the gum tissue affects the health of the bone around dental implants over ten years. We include 59 people and divide them into three groups based on their gum tissue thickness.
- Trial name
- NCT06302322
- Testing
- Thin Tissues, Thick Tissues, Surgically augmented thin tissues
- Where
- Lithuania
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)