Clinical trials: Soft Tissue
Pain
Brainwave Activity Response on Common Physical Therapy Intervention
This study is designed to evaluate the if there is a predictable patterns in brainwave activity and to see how this changes with external physical therapy interventions such as manipulation, soft tissue massage, and exercise.
- Trial name
- NCT04542707
- Testing
- joint manipulation, Exercise, Soft tissue massage
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Florida Gulf Coast University
Dupuytren Contracture, Dupuytren's Disease
Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture
Dupuytren's contracture (DC) is associated with progressive finger flexion and extension deficit caused by fibrosis in the palm and digits.
- Trial name
- NCT05300893
- Testing
- No night splint
- Where
- 3 sites in Sweden
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Healthy Volunteers
The Effects of IASTM and Proprioception
The research design will be single group pretest-posttest design. The subject will be instructed to position the knee joint to a position previously set by the experimenter.
- Trial name
- NCT03023943
- Testing
- Instrument Assisted Soft Tissue Mobilization
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Youngstown State University
Sarcoma
A First-in-Human Study of ¹⁷⁷Lu-HX02 in Sarcoma Patients
This is a single-center, open-label clinical study to evaluate the safety, biodistribution, and dosimetry of ¹⁷⁷Lu-HX02 injection in patients with sarcoma.
- Trial name
- NCT07847268
- Testing
- Safety, Biodistribution, and Dosimetry of ¹⁷⁷Lu-HX02 in Patients with Sarcoma
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Retroperitoneal Sarcoma, Margin, Tumor-Free
Retroperıtoneal Soft-Tıssue Sarcomas
: Soft Tissue Sarcomas are rare mesenchymal tumors with many subtypes. Clean margin-wide resection is recommended for treatment. The guidelines recommend that sarcoma treatments be carried out in sarcoma centers.
- Trial name
- NCT05044624
- Testing
- retroperitoneal mass excision
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Peri-Implantitis
Treatment of Peri-implantitis With or Without Simultaneous Soft Tissue Augmentation
The study will aim to compare two modalities in the reconstructive treatment of peri-implantitis defects. More specifically, the control group will be a reconstructive approach (xenograft bone graft granules and collagen…
- Trial name
- NCT04323540
- Testing
- Peri-implantitis reconstructive surgery
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- George Eastman Dental Hospital, Italy
Osteosarcoma, Ewing Sarcoma
Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone Sarcoma
Osteosarcoma and Ewing sarcoma treatment has not changed in the last 30 years. For other types of cancer the epidemiologic and prognostic correlations between dietary behavior, lifestyle and metabolic alterations (i.e.obesity…
- Trial name
- Metabol-Sarc (NCT04735289)
- Testing
- EPIC-COS Food Frequency Questionnaire diet Evaluation, Metabolome, Microbiota, Lymphocytes subpopulations
- Where
- 7 sites in Italy
- Volunteers
- 810 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
De Quervain Syndrome
Mobilization With Movement Versus Soft Tissue Mobilization in Patients With De Quervain Tenosynovitis
this study will investigate the effects of mobilization with movement in addition to soft tissue mobilization on pain and range of motion in patients suffering from De Quervain Tenosynovitis.
- Trial name
- NCT05356624
- Testing
- Mulligan Mobilization, Soft Tissue Mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Skin Aging, Skin Wrinkling
Efficacy and Performance Evaluation of mIntense L+AS 25 mg/ml Hyaluronic Acid for the Correction of Moderate to Deep Wrinkles and Folds
The investigation is a single-centre, interventional, prospective, non-randomized, open-label, uncontrolled, single-arm, un-blinded investigation for evaluation of the safety and performance of the product mIntense L+AS in the…
- Trial name
- M-INT-LS (NCT06451822)
- Testing
- mIntense L+AS
- Where
- Bulgaria
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Dental Implants
Soft Tissue Response to Peek and Ti Healing Abutments
Introduction: Single-stage dental implant placement protocol involves the placement of healing abutments. In addition to osseointegration process, healing of peri-implant soft tissues is of a great importance too.
- Trial name
- NCT04436939
- Testing
- Dental implant
- Where
- Serbia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Hamstring Muscle Shortness and Elastographic Examination
Effects of Dry Needling, Static Stretching and IASTM in People With Hamstring Muscle Shortness
This randomized controlled trial compared the effects of dry needling, static stretching and instrument-assisted soft tissue mobilization (IASTM), each applied three times per week for four weeks, with a no-intervention control…
- Trial name
- NCT04118231
- Testing
- Dry needling, IASTM, Static stretching
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession, Generalized, Graft Reaction
The Healing of Soft Tissue Augmentation by Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft
The study team proposes to prospectively compare the healing outcomes of autogenous soft tissue connective tissue graft (CTG) and Acellular dermis matrix (ADM) in a split-mouth design study for patients requiring modification of…
- Trial name
- NCT03954028
- Testing
- Gingival Punch Biopsy after healing of Gingival Soft Tissue Augmentation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Dynamic Knee Valgus, Force Production
Investigation of the Effect of Instrument Assisted Soft Tissue Mobilization Technique in Individuals With Asymptomatic Dynamic Knee Valgus
STUDY DESIGN: Randomized controlled study OBJECTIVES: To investigate the contribution of instrument assisted soft tissue mobilization (IASTM) applied to gluteus medius (GMed) to isokinetic strength, femoral internal rotation…
- Conditions
- Dynamic Knee Valgus, Force Production, Frontal Plan Projection Angle, Instrument-assisted Soft Tissue Mobilization
- Trial name
- NCT04660604
- Testing
- Graston Technique®
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Implant or Graft; Rejection
Implant Placement in Horizontally Deficient Maxillary Aesthetic Zone With Simultaneous Soft Tissue Augmentation
Tooth extraction in maxillary esthetic zone is accomplished with great dimensional changes of the alveolar ridge, different procedures have been tested to compensate these dimensional alteration, such as Hard bone augmentation…
- Trial name
- NCT05274256
- Testing
- implant placement with simultaneous soft tissue augmentation
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skin Laxity
Measuring Renuvion Soft Tissue Contraction Using Ultrasound
This is a prospective, single-center, non-randomized study of up to 5 subjects who are receiving treatment with the Renuvion APR system following power-assisted liposuction in the abdomen per investigator standard of care.
- Trial name
- NCT05968495
- Testing
- Renuvion APR Handpiece
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Apyx Medical
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Skin Laxity
Sculptra to Aid in Treatment of Arm Laxity
To assess the safety, efficacy, and patient satisfaction associated with the treatment of upper inner arm crepiness/laxity with injectable poly-L-lactic acid (PLLA, Sculptra® Aesthetic; Galderma Laboratories; Fort Worth, TX).
- Trial name
- NCT05445661
- Testing
- injectable poly-L-lactic acid, Normal Saline
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Comparative Study
Soft Tissue Graft Versus Acellular Dermal Matrix in Preservation of Buccal Plate of Bone
Comparative study between 2 groups to assess the feasibility of using Acellular dermal matrix vs Soft tissue Graft after immediate implant placement
- Trial name
- NCT06229561
- Testing
- Acellular Dermal Matrix
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Myoma
Prevention of Intra-uterine Adhesions Following Laparoscopic and Laparotomic Myomectomy
Clinical study on the prevention of intrauterine adhesions after laparoscopic or laparotomic myomectomy. Myomas are common in women of reproductive age and myomectomy can lead to intra-uterine adhesions, which can be detrimental…
- Trial name
- PALLM (NCT05683041)
- Testing
- Hyalobarrier
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Uterine Fibroid, Myoma;Uterus
INTERVENTION WITH TRANEXAMIC ACID TO REDUCE HAEMORRHAGE DURING LAPAROSCOPIC MYOMECTOMY
This research is planned as a randomised double-blind controlled trial. interventions to reduce haemorrhage during laparoscopic myomectomy for fiboids is important.
- Conditions
- Uterine Fibroid, Myoma;Uterus, Tranexamic Acid Adverse Reaction
- Trial name
- NCT04192643
- Testing
- Tranexamic Acid 100 MG/ML
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alkü Alanya Education and Research Hospital