Clinical trials: Soft Tissue
Lip Augmentation
New Dermal Filler for Lip Augmentation
To demonstrate non-inferiority of Kysse versus a control in lip fullness augmentation
- Trial name
- NCT03320824
- Testing
- New Dermal Filler, Device: FDA Approved Dermal Filler
- Where
- 14 sites in United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Leiomyoma, Vitamin D Deficiency
Vitamin D Deficit in Women With Uterine Fibroids
Determinate the level of vitamin D in blood, and evaluate the prevalence of deficit and insufficiency among patients with diagnosis of uterine fibroids
- Conditions
- Leiomyoma, Vitamin D Deficiency, Fibroid Uterus
- Trial name
- NCT04030182
- Testing
- Level of Vitamin D
- Where
- 2 sites in Mexico
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Edentulous Alveolar Ridge
The Role of a New Prosthodontics Device in Hard and Soft Tissue Changes After Subcrestal Implant Placement
The present randomized controlled trial aims to assess the influence of a new prosthodontics device (Gingival Former Abutment -GFA) on peri-implant bone loss and soft tissue changes and health after subcrestal oral implant…
- Trial name
- NABUT (NCT06182670)
- Testing
- Gingival Former Abutment, Subcrestal Implant, Healing Abutment
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Soft Tissue Atrophy
Peri-Implant Soft Tissue Augmentation Using a Free Connective Tissue Graft With an Epithelial Collar
A prospective randomized interventional clinical trial (RCT) with a parallel-group design is planned. The study sample will include 32 patients randomly allocated into two groups according to the surgical intervention performed.
- Trial name
- NCT07626866
- Testing
- Free connective tissue graft without an epithelial collar, Free connective tissue graft with epithelial collar
- Where
- Russia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Mucositis
Surgical Protocol for Prevention of Mucositis
The main goal of implant therapy is to obtain long-term peri-implant health. Among local risk factors in the etiology of peri-implant diseases the absence of keratinized tissue (KT) around the implant has been reported.
- Trial name
- NCT04628520
- Testing
- Free gingival graft, Collagen matrix, Maintenance
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Cervical Cancer, Ovarian Cancer
Clinical Database and Biobank of Patients With Gynecologic Neoplasms
The database and biobank establishment started in 1997 in our institute. However, the sample size was too small with respect to our clinical and fundamental scientific research's requirement.
- Conditions
- Cervical Cancer, Ovarian Cancer, Endometrial Cancer, Choriocarcinoma
- Trial name
- NCT01267851
- Where
- China
- Volunteers
- 1,600,000 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Uterine Leiomyoma
Trial of a Patient Education Tool For Leiomyoma
The goal of this study was to assess whether using a multimedia tool would enhance patient education and counseling on uterine leiomyomata.
- Trial name
- PETAL (NCT03847077)
- Testing
- iPad counseling, Standard Counseling
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Loyola University
Dental Implants
Evaluation of Soft and Hard Tissue Healing and Implant Stability Of Hydrophilic Versus Conventional Titanium Dental Implants.
Dental implants have become more common treatment for replacing missing teeth and aim to improve chewing efficiency, physical health and esthetic.
- Trial name
- NCT06519019
- Testing
- Dental Implant Surgery - Hydrophilic group, Dental Implant Surgery - Conventional group
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Mastocytosis, Healthy Volunteer
Study of Mast Cell Precursors
This study will investigate mast cell precursors that circulate in the blood. In a group of diseases collectively known as mastocytosis, mast cells accumulate in abnormal amounts in the skin, lymphoid tissues, bone marrow, liver…
- Trial name
- NCT00001756
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Peri-Implantitis, Soft Tissue
Association of Keratinised Mucosa Around Implants and Teeth With Peri-implant/Periodontal Disease and Soft Tissue Conditioning
Lack of keratinised mucosa around dental implants and teeth is associated with plaque accumulation and worse tissue conditions. However, there is lack of data on the influence of the presence/lack of keratinised mucosa on the…
- Conditions
- Peri-Implantitis, Soft Tissue, Bone Gain
- Trial name
- NCT03501537
- Testing
- Free gingival graft obtained from the palate and debridement of the peri-implant lesion
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Bone Resorption
Timing of Soft Tissue Grafting Following Immediate Implant Placement
Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT).
- Trial name
- NCT05537545
- Testing
- Soft tissue grafting
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Osteoarthritis of the Knee
Computer Aided Gap Balancing Improves Sagittal Stability and Outcomes for Cruciate-Retaining Total Knee Arthroplasty
Computer Aided Surgery in total knee arthroplasty improves knee stability and functional outcomes more than conventional total knee arthroplasty.
- Trial name
- NCT00865865
- Testing
- Computer aided total knee arthroplasty, Conventional total knee arthroplasty
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Soft Tissue Augmentation
Evaluation of Self-filling Osmotic Tissue Expander in Augmenting Keratinized Tissue Around Dentulous Region
The present study is a human, prospective, single centre, single blind randomised controlled clinical tria conducted to explore the feasibility and efficacy of self-inflating hydrogel expander (Osmed®) to gain keratinised tissue…
- Trial name
- NCT03753906
- Testing
- Osmed® hydrogel expander implantation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Wound Healing After Tooth Extraction
Comparing Cross-Linked and Non-Cross-Linked Hyaluronic Acid for Early Healing After Tooth Extraction
This study compares early healing after a non-surgical tooth extraction in adults. Participants are assigned by chance to one of three groups: cross-linked hyaluronic acid placed in the extraction site using a gelatin sponge…
- Trial name
- NCT07898163
- Testing
- Cross-linked sodium hyaluronate 1%, Non-cross-linked low-molecular-weight hyaluronic acid, Gelatin sponge
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cyprus Health and Social Sciences University
Soft Tissue Injuries
Effectiveness of Phentolamine Mesylate as a Reversing Agent for Local Anesthesia in Children
Local anaesthesia is considered one of the most alarming and non-comfortable dental procedures for children. This goes back to the persisting effect of the local anaesthesia after finishing dental procedures.
- Trial name
- NCT05448807
- Testing
- OraVerse
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Customized Healing Abutment, Dental Implant
A Comparison Between Protemp and Flowable Light Cure Composite Material for Creating Optimal Gingival Emergence Profile Around Implant
The study focuses on the critical role of the gingival emergence profile in the success of dental implants, emphasizing its importance for both peri-implant health and esthetics.
- Conditions
- Customized Healing Abutment, Dental Implant, Composite Resin, Peri-Implant Health
- Trial name
- NCT07196293
- Testing
- Customized Healing Abutment - bulk fill composite, customized healing abutments - Bis acryl composite materials
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Amrita Institute of Medical Sciences & Research Center
Desmoid Tumor, Desmoid Fibromatosis
A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patients With Desmoid Tumors
This is a prospective study on the safety and effectiveness of radiofrequency ablation in patients with desmoid tumors. In the study group, all patients after radiofrequency ablation of the tumor after 1 month will be evaluated…
- Conditions
- Desmoid Tumor, Desmoid Fibromatosis, Desmoid
- Trial name
- RFAdesmoid (NCT06355921)
- Testing
- radiofrequency ablation
- Where
- Russia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Blokhin's Russian Cancer Research Center
Localized Gingival Recession
Use of a Collagen Membrane for Soft Tissue Grafting
Is PriMatrix wound dressing capable of regenerating gum tissue inside the mouth?
- Trial name
- NCT02206009
- Testing
- Collagen Membrane
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lauren M. F. Syrowik
Cervical Pain, Posterior, Musculoskeletal Disorder of the Neck
Investigation of the Immediate Effect of IASTM on Some Parameters in E-Sports Players
Due to the nature of competitive sports, frequent and regular training by e-sports players to increase their performance provides e-athletes with success in the field, but it also increases the time spent in front of the screen.
- Conditions
- Cervical Pain, Posterior, Musculoskeletal Disorder of the Neck, Neck Pain, Posture
- Trial name
- IASTM (NCT07006363)
- Testing
- IASTM
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Subacromial Impingement Syndrome, Massage
IASTM Effects on Pain, Functionality, and Proprioception in Subacromial Impingement
The aim of this study will be to investigate the effects of Instrument-Assisted Soft Tissue Mobilization (IASTM), applied in addition to a conventional exercise program, on pain, range of motion, proprioception, functionality…
- Conditions
- Subacromial Impingement Syndrome, Massage, Instrument-Assisted Soft Tissue Mobilization, Soft Tissue Injuries
- Trial name
- NCT07293702
- Testing
- Conventional exercise group, IASTM group
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital