Clinical trials: Soft Tissue Neoplasm
Myoma, Surgery
Impact of Uterine and Ovarian Vessel Occlusion on Blood Loss in High Burden Minimally Invasive Myomectomy.
This study hypothesizes that temporary bilateral uterine and utero-ovarian artery occlusion with laparoscopic clamps at time of minimally invasive myomectomy will lead to a decreased blood loss at time of myomectomy compared to…
- Trial name
- Myo-Bleed (NCT07182045)
- Testing
- Temporary clamping of uterine and ovarian vessels
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Endometrial Cancer, Endometrial Diseases
Virtual Reality's Role in See&Treat Hysteroscopy
The aim of the study is to evaluate the feasibility and effectiveness of virtual reality technology in outpatient hysteroscopy to improve pain and anxiety management and spread the diffusion of see \& treat philosophy.
- Conditions
- Endometrial Cancer, Endometrial Diseases, Myoma;Uterus, Endometrial Hyperplasia
- Trial name
- NCT06524934
- Testing
- Use of virtual reality during the hysteroscopic procedure
- Where
- Italy
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Federico II University
Uterine Fibroid, Myoma;Uterus
OPPIuM Technique and Myolysis With Diode Laser Dwls
PURPOSE OF THE STUDY The study aims to examine the feasibility and effectiveness of the OPPIuM technique combined with myolysis using the DWLS diode laser.
- Trial name
- Myolysis (NCT04748978)
- Testing
- hysteroscopy
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Infertility
The Effect of Ulipristal Acetate (UPA) on Women Ovarian Reserve
The uterine leiomyoma is the most common female benign disease.UPA seems to be most effective for the medical management of fibroids and could be place as preoperative adjunct to surgery but also as medical therapy to avoid…
- Trial name
- UPA_ovAge (NCT02361892)
- Testing
- ulipristal acetate
- Where
- Italy
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Uterine Fibroids
Endometrial Preparation Before Operative Hysteroscopy in Premenopausal Women
The presence of a thin endometrium has an important role in allowing the best conditions for hysteroscopic surgery. The aim of this study is to evaluate the efficacy of a 21 day administration of 2 mg of dienogest versus…
- Trial name
- NCT02440750
- Testing
- operative hysteroscopy, Dienogest, Ulipristal acetate
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Mastocytosis, Bones
Relationship Between Circulating Sclerostin and Bone Lesions in Patients With Mastocytosis
Mastocytosis is very rare and highly heterogeneous group of disorders, characterized by the accumulation of clonal mast cells which can infiltrate several organs and tissues.
- Trial name
- NCT06440148
- Testing
- SCLEROSTIN
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Angioedema, Angioedemas, Hereditary
Angioedema Biomarker Research Study
This clinical trial aims to evaluate and compare novel and commercially available diagnostic assays through blood tests for the differential diagnosis and comprehensive assessment of patients experiencing recurrent angioedema…
- Conditions
- Angioedema, Angioedemas, Hereditary, Urticaria, Mastocytosis
- Trial name
- NCT06210698
- Testing
- Venipuncture
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Foundation For Rare Disease Research
Sarcoma
Aranesp and Neulasta in Patients With Sarcoma Receiving Adriamycin and Ifosfamide
To determine the percentage of patients and number of cycles in which a packed red blood cell transfusion was administered due to anemia and in which antibiotics were administered due to neutropenic fever.
- Trial name
- NCT00283621
- Testing
- Aranesp (darbepoetin alfa), Neulasta (pegfilgrastim), Adriamycin
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Leukemia, Lymphoma
A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation From Related or Matched Unrelated Donors in Pediatric Patients With Solid Tumors and Leukemias
Background: Bone marrow stem cells, which are found in the bone marrow and blood stream, can be collected and transplanted to treat a variety of types of cancer in a process known as hematopoietic stem cell transplantation…
- Trial name
- NCT01287104
- Testing
- Natural Killer (NK) Cell Infusion, Stem Cell Infusion
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Minor Intra-uterine Abnormalities
The Impact of Treating Minor Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy in Unselected In Vitro Fertilization (IVF) Cases
This is a comparative, controlled trial to evaluate the impact of treating undetected, asymptomatic, predefined minor uterine cavity abnormalities on the success of IVF treatment.
- Trial name
- NCT00830401
- Testing
- Treatment of predefined abnormality by hysteroscopic surgery, Ofloxacinum/Doxycycline
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Liposarcoma, Atypical Lipomatous Tumor
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas
The main objective of this project is to identify a new non-invasive biological test for the diagnosis of LPS by measuring circulating serine levels. The current gold standard is the detection of Mdm2 amplification by the FISH.
- Trial name
- ESPACE (NCT04224064)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle