Clinical trials: Solid Pancreatic Masses
Solid Pancreatic Masses
Clinical Research on a Novel Deep-learning Based System in Pancreatic Mass Diagnosis
In this study, a single-center, prospective, self-control, and blind design was adopted.
- Trial name
- NCT04607720
- Testing
- artificial-EUS-FNA, AI-EUS-FNA
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Solid Pancreatic Masses
Endoscopic Ultrasound-guided Fine Needle Biopsy With 25-gauge Biopsy Needles for Solid Pancreatic Masses
For 12 months after approvement by the University of Yonsei institutional review board, of the 59 patients older than 20 years referred to our medical center for EUS-FNA or FNB, all consecutive pancreatic lesions were evaluated…
- Trial name
- NCT01795066
- Testing
- EUS-FNB with 25-gauge (Echotip ProCore; Cook Endoscopy Inc, Limerick, Ireland)
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Pancreatic Masses
RCT Comparing Accuracy Among Franseen, Forward-bevel Westcott, and Fork-tip EUS-FNB Needle in Diagnosis of Solid Pancreatic Lesions
Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) is a well-established technique for pancreatic tissue acquisition, offering a high diagnostic accuracy ranging from 78% to 95%, along with a favorable safety profile.
- Trial name
- NCT07032974
- Testing
- Franseen, Forward-bevel, Fork-tip
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Mahidol University
Pancreas Mass Diagnosis
Comparing Methods to Biopsy Pancreas Mass
This study will examine whether there is any difference in number of passes needed to diagnose pancreatic masses during endoscopic ultrasound-guided biopsies using 2 different types of needles.
- Trial name
- NCT01663493
- Testing
- FNB
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Brigham and Women's Hospital
Pancreatic Cancer, Endoscopic Ultrasound
Ex-vivo Ultrasound Guided Radiofrequency Ablation on Pancreatic Solid Lesions
The study investigates the feasibility and the efficacy to treat pancreatic solid lesions as pancreatic adenocarcinomas (PDAC) and neuroendocrine tumors (NET) with ex-vivo radiofrequency ablation (RFA) under ultrasound (US)…
- Conditions
- Pancreatic Cancer, Endoscopic Ultrasound, Radiofrequency Ablation
- Trial name
- NCT06371716
- Testing
- ex-vivo RFA under US control at 10 Watts (W) of power in 3 differents arms of lesions, ex-vivo RFA under US control at 30 Watts (W) of power in 3 differents arms of lesions, ex-vivo RFA under US control at 50 Watts (W) of power in 3 differents arms of lesions
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS San Raffaele
Fine Needle Aspiration, Pancreatic Mass
EUS FNB Versus FNA With On-Site Cytopathology in Solid Pancreatic Masses
The objective of this paired cohort study is to evaluate the diagnostic accuracy of Endoscopic Ultrasound-fine needle aspiration (EUS-FNA) with rapid onsite evaluation (ROSE) compared to EUS-fine needle biopsy (EUS-FNB) without…
- Trial name
- NCT03485924
- Testing
- EUS-FNA with ROSE, EUS-FNB without ROSE
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Pancreatic Neoplasms
Comparative Study of 22 and 25 Gauge ProCore EUS-guided Biopsy in Pancreatic Mass
Background: EUS-guided fine needle aspiration (FNA) is a major diagnostic tool in the patient with pancreatic mass with high specificity, specificity and accuracy.
- Trial name
- NCT01727921
- Testing
- 22 gauge ProCore needle biopsy, 25 gauge ProCore needle biopsy
- Where
- South Korea
- Volunteers
- 219 people
- Sponsor
- Samsung Medical Center
Solid Pancreatic Masses
Endoscopic Ultrasound-guided Needle-based Confocal Laser Endomicroscopy in Solid Pancreatic Masses
The differential diagnosis of solid pancreatic masses by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is currently suboptimal.
- Trial name
- NCT02936960
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shandong University
Cancer of Pancreas, Cancer of Stomach
Wet Heparinized Suction for Abdominal Cancer
The purpose of this research is to compare the amount and quality of tissue obtained by EUS-FNB when the device is flushed with an anticoagulant or "blood thinner" vs.
- Conditions
- Cancer of Pancreas, Cancer of Stomach, Cancer of Esophagus, Cancer of Liver
- Trial name
- EUS Heparin (NCT05041335)
- Testing
- wet heparinzed suction, Microsieve, No heparin flush
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Endoscopic Ultrasonography
The Added Value of Contrast Enhancement for Guiding EUS-FNA in Solid Pancreatic Masses
A prospective study designed to show the superiority of contrast guided echoendoscopy versus conventional echoendoscopy
- Trial name
- NCT03525847
- Testing
- Endosonography
- Where
- Romania
- Volunteers
- 150 people
- Sponsor
- Professor Dr. Seicean Andrada
Pancreas Cancer, Pancreas Neoplasm, Benign
Endoscopic Ultrasound Guided Tissue Sampling (The SharkBITE Study)
This study compares the diagnostic performance of Endoscopic ultrasound (EUS) guided fine needle aspiration and EUS guided core biopsy (SharkCore) in patients with a solid pancreatic mass.
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Benign, Chronic Pancreatitis, Pancreas Adenocarcinoma
- Trial name
- SharkBITE (NCT03532347)
- Testing
- EUS-FNA needle (Beacon)
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Pancreatic Cancer, Solid Pancreatic and Peripancreatic Lesion
Yield Rate for Procurement the Histologic Core With Endoscopic Ultrasound-guided Fine Needle Biopsy With 20-gauge Ultrasound Biopsy Needles for Solid Pancreatic Masses: Pilot Study
To investigate the technical feasibility and diagnostic yield of new 20-gauge Procore needle for EUS-guided fine needle biopsy in pancreatic solid lesions.
- Trial name
- NCT03017599
- Testing
- 20-gauge ProCore FNB needle
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Pancreatic Neoplasm
Comparison of Two Fine Needle Biopsy Needles for Solid Pancreatic Masses
This is a randomized prospective clinical study comparing the Acquire Biopsy Device to SharkCore Biopsy Device.
- Trial name
- Expect (NCT02910960)
- Testing
- Acquire EUS Biopsy Device, SharkCore Biopsy System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- AdventHealth
Pancreatic Masses
The Use of a New Core Needle in the Endoscopic Ultrasound Assisted Tissue Sampling for Pancreatic Solid Masses
Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) is a reliable, safe, and effective technique for obtaining samples from pancreatic masses.
- Trial name
- NCT02946840
- Testing
- FNA with 25 G Beacon needle
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Clinico Humanitas
Pancreatic Adenocarcinoma, Pancreas Cancer
Repeated EUS-guided Fine Needle Biopsy of Pancreatic Masses After Non-diagnostic or Inconclusive Results
The primary aim of REuBio study is to evaluate the diagnostic accuracy of repeated endoscopic ultrasound-guided fine needle biopsy after a previous non-diagnostic or inconclusive EUS-guided sampling of solid pancreatic lesions.
- Conditions
- Pancreatic Adenocarcinoma, Pancreas Cancer, Pancreas Metastases
- Trial name
- REuBio (NCT05226572)
- Testing
- endoscopic ultrasound-guided fine needle biopsy
- Where
- Italy
- Volunteers
- 462 people
- Sponsor
- University of Bologna
Pancreatic Tumor, Puncture
Comparison of Two Endoscopic Biopsic Needles for Pancreatic Tumors
This observational study compared quality of histological sampling of pancreatic EUS-FNB with the 20-gauge Procore® and 22-gauge Acquire® needles. In total, 68 patients were recruited.
- Trial name
- Mousquetaires (NCT03444051)
- Testing
- EUS-FNB with 20-gauge Procore® needle, EUS-FNB with 22-gauge Acquire® needle
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Société Française d'Endoscopie Digestive
Submucosal Tumor, Pancreas Tumor
25G and 22G Puncture Needles
The screened patients were randomly assigned 25G puncture needles and 22G puncture needles in a 1;1 ratio, based on the computer-generated random order, before receiving an ultrasound endoscope puncture.
- Trial name
- NCT05101772
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatic Neoplasm, Magnetic Resonance Imaging
MRE for Diagnosis of Pancreatic Masses
Pancreatic ductal adenocarcinoma (PDAC) accounts for 85-95% of pancreatic cancer and is one of the deadliest tumors in the world, with a survival rate of less than 8%, and identifying key prognostic or predictive factors…
- Trial name
- MREDPCM (NCT06526442)
- Testing
- magnetic resonance imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yu Shi
Pancreatic Neoplasm
Comparing Biopsy Needles for Endoscopic Ultrasound Guided Samples for Pancreatic Masses
This is a randomized prospective clinical study comparing a fine needle biopsy device and an aspiration needle.
- Trial name
- Expect (NCT02911974)
- Testing
- Acquire EUS Biopsy Device, Expect EUS Aspiration Needle
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- AdventHealth
Pancreatic Neoplasms
Comparison Between Olympus EZ Shot 3Plus 19G and EZ Shot 2 19G in EUS-guided FNB of Solid Pancreatic Masses
Endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) is a valid and recommended technique for tissue diagnosis of pancreatic masses.
- Trial name
- NCT02909530
- Testing
- EUS-FNB with EZ Shot 3Plus first, EUS-FNB with EZ Shot 2 19G first
- Where
- 4 sites in Germany
- Volunteers
- 46 people
- Sponsor
- University of Ulm