Clinical trials: Sound Perception
Cochlear Hearing Loss
Investigation of the Automatic Technology on the Naída M Hearing Devices
In this clinical trial, an un-controlled, repeated measures open design with within-subject comparison will be used to evaluate the effect of the device under investigation on sound perception.
- Trial name
- NCT04610216
- Testing
- Naida CI M hearing device
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Advanced Bionics AG
Hearing Loss
Quality Control of CE-Certified Phonak Hearing Aids - 2019_34
Phonak Hearing Devices pass through different development and study phases. At an early stage, feasibility studies are conducted to investigate new algorithms, features and functions in an isolated manner.
- Trial name
- NCT04187781
- Testing
- external microphone
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- Sonova AG
Sensorineural Hearing Loss, Bilateral, Cochlear Implant
Clinical Investigation of New CI Delivery Models in an Adult Nucleus CI Population
Use of Artificial Intelligent (AI) technology to assist audiologists in programming cochlear implants.
- Trial name
- NCT03304106
- Testing
- Commercially available cochlear implant and AI system
- Where
- 9 sites in United States
- Volunteers
- 102 people
- Sponsor
- Cochlear
Bilateral Hearing Loss
Evaluation of the Benefits of Bilateral Fitting in BAHS Users
The purpose of this study is to evaluate the benefit of bilateral implantation with bone-anchored hearing systems (BAHS), in terms of sound localization abilities, as well as auditory working memory.
- Trial name
- NCT04006132
- Testing
- Fitting of Ponto 3 SuperPower
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oticon Medical
Tinnitus
Efficacy of the Erchonia Corporation THL™ for Providing Relief of Tinnitus Symptoms
The purpose of this clinical study is to determine the effectiveness of the Erchonia® THL™, manufactured by Erchonia Corporation (the Company), for prescription home use in providing relief of tinnitus symptoms when used by…
- Trial name
- NCT05374421
- Testing
- Erchonia® THL™
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Erchonia Corporation
Conductive Hearing Loss
Comparison of a New Bone Conduction Hearing System to a Osteo-integrated Bone Conduction Hearing Aid on a Softband
Main objectives The first main objective is to evaluate the non-inferiority of the ADHEAR system compared to the PONTO 3 SUPERPOWER softband system in terms of average tonal gain.
- Trial name
- NCT03541967
- Testing
- ADHEAR and PONTO 3 SUPER POWER on softband hearing aids
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Hearing Loss, Sensorineural
Evaluation of the Efficacy and Safety of the Sullivan Cochlear Implant.
The study will be conducted as a prospective, single center, repeat measure, single-arm, open label clinical study
- Trial name
- NCT07018882
- Testing
- Sullivan
- Volunteers
- 25 people
- Sponsor
- Todoc
Tinnitus
Acoustic Coordinated Reset (CR®) Neuromodulation for the Treatment of Chronic Tonal Tinnitus ("RESET Real Life")
Confirmation of efficacy and safety of acoustic CR®-neuromodulation for the treatment of chronic tinnitus patients using the CE marked ANM T30 CR®-system in a real life outpatient setting.
- Trial name
- RRL (NCT01435317)
- Testing
- ANM T30 CR®-System
- Where
- 23 sites in Germany
- Volunteers
- 200 people
- Sponsor
- ANM Adaptive Neuromodulation GmbH
Migraine
Randomized Trial in Adult Participants With Acute Migraines
The purpose of this study is to test the safety and efficacy of BHV-3500 (zavegepant) versus placebo in the acute treatment of moderate or severe migraine.
- Trial name
- NCT04571060
- Testing
- Zavegepant
- Where
- 94 sites in United States
- Volunteers
- 1,978 people
- Sponsor
- Pfizer
Hearing Loss
Ponto Implantation Using a Minimally Invasive Surgical Technique
This multi-centre study funded by Oticon Medical AB will be conducted at seven hospitals across Europe (UK, Sweden, Denmark and the Netherlands).
- Trial name
- NCT04606823
- Testing
- Minimally invasive surgery, Glasgow Benefit Inventory (GBI), Additional follow-up visits after surgery
- Where
- 7 sites in Denmark, Netherlands and 2 more
- Volunteers
- 52 people
- Sponsor
- Oticon Medical
Single Sided Deafness, Conductive Hearing Loss
SoundBite Hearing System 24 Month Multi Site Patient Use Study
The objective of this multi-site observational study is to further assess the long-term patient use of the Sonitus SoundBite Hearing System.
- Trial name
- NCT01807559
- Testing
- SoundBite Hearing System
- Where
- 7 sites in United States
- Volunteers
- 75 people
- Sponsor
- Sonitus Medical Inc
Hearing Loss
Clinical Performance, Safety and Patient Reported Outcomes of an Active Osseointegrated Steady-State Implant System
The aim of this clinical investigation is to collect data on objective and subjective hearing performance, quality of life and safety in adult subjects with conductive hearing loss, mixed hearing loss or single-sided…
- Trial name
- NCT04041700
- Testing
- Osia 2 system
- Where
- 3 sites in Australia, Hong Kong
- Volunteers
- 29 people
- Sponsor
- Cochlear
Sensorineural Hearing Loss
OTO-413 in Subjects With Speech-in-Noise Hearing Impairment
The purpose of this study is to evaluate the safety, tolerability, and exploratory efficacy of OTO-413 administered as an intratympanic injection for the treatment of speech-in-noise hearing impairment.
- Trial name
- NCT04129775
- Testing
- OTO-413
- Where
- 8 sites in United States
- Volunteers
- 110 people
- Sponsor
- Otonomy, Inc.
Hearing Loss
The Effects of Ultrasonic Noise Exposure on Human Hearing
The aim of this research is to investigate the effects of ultrasonic noise exposure on the human auditory system (how it effects hearing).
- Trial name
- NCT03515928
- Testing
- Ultrasonic noise exposure, Pure Tone Audiometry
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ultrahaptics Ltd
Presbyacusis
Development of a Battery of Audiological Tests for the Precision Diagnosis of Age-related Hearing Loss
Age-related hearing loss, or presbycusis, is caused by many genetic and environmental factors. Its prevalence poses a public health challenge of early identification and effective hearing aid treatment.
- Trial name
- AUDIOGENAGE (NCT05312983)
- Testing
- Audiological and vestibular tests, Blood sampling, neurocognitive self-questionnaire
- Where
- 2 sites in France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Hearing Disorders and Deafness
Cognitive Processing of Natural Sequences in Humans and Artificial Intelligence (AI)
The goal of this study is to identify electrical patterns in the cortex that enable the generation of predictions in natural auditory sequences such as speech and music.
- Trial name
- SEQUOIA (NCT07740070)
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Mixed Hearing Loss
Long Term Results With the Vibrant Soundbridge in Patients With Mixed Hearing Loss: a 60-month Longitudinal Study
Vibrant Soundbridge (VSB, MED-EL, Innsbruck) Active middle ear implants (AMEI) can benefit patients who are unable to use conventional hearing aids (HA) due to medical reasons, discomfort or unsuccessful rehabilitation.
- Trial name
- NCT05793580
- Testing
- Vibrant Soundbridge active middle ear implant
- Where
- France
- Volunteers
- 31 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Hearing Loss
Retrospective CI532 Hearing Performance
The aim of this retrospective study is to collect and assess hearing performance data that have been measured by five clinics in Germany as part of their clinical routine in recipients implanted with a commercial CI532.
- Trial name
- NCT03039283
- Testing
- Nucleus CI532 cochlear implant
- Where
- 5 sites in Germany
- Volunteers
- 162 people
- Sponsor
- Cochlear
Tinnitus
An Open-Label Study Evaluating Brexanolone in Adults With Tinnitus
The primary objective of this study is to evaluate the safety and tolerability of brexanolone in participants with tinnitus following a single 6-hour continuous intravenous (IV) infusion.
- Trial name
- NCT05645432
- Testing
- Brexanolone
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Autoimmune Inner Ear Disease
The Effects of Gevokizumab in Corticosteroid-resistant Subjects With Autoimmune Inner Ear Disease
The purpose of this study is to determine if gevokizumab therapy may be an alternate therapy in patients with steroid resistant Autoimmune Inner Ear Disease.
- Trial name
- NCT01950312
- Testing
- gevokizumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- XOMA (US) LLC