Clinical trials: Spasmodic Torticollis
Cervical Dystonia
Abobotulinum Toxin and Neubotulinum Toxin Injection in Cerivical Dystonia
A 48-Week Prospective, Double-Blinded, Randomized, Cross-over design in Multicenter Study of, 250 unit of Abobotulinum Toxin Type A (Dysport) and 50 unit of Neubotulinum Toxin Type A (Neuronox) injection for Cervical Dystonia in…
- Trial name
- DNCD (NCT03805152)
- Testing
- Neuronox(R), Dysport (R)
- Where
- 4 sites in Thailand
- Volunteers
- 52 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Cervical Dystonia
Longitudinal Study for Treatment With Botulinum Toxin A Injections in naïve and Pre-treated Patients Suffering From Cervical Dystonia [CD-NIS-Longterm]
The objective of this study is to investigate the efficacy of Dysport® in the treatment of cervical dystonia (CD) in a non-interventional long-term study in naïve and pre-treated patients.
- Trial name
- CDNISLongterm (NCT01840462)
- Where
- 2 sites in Austria, Germany
- Volunteers
- 372 people
- Sponsor
- Ipsen
Blepharospasm, Hemifacial Spasm
Post Marketing Surveillance Study of Dysport
The purpose of this study is to provide further information regarding the risks and benefits of Dysport in marketed indications.
- Conditions
- Blepharospasm, Hemifacial Spasm, Cervical Dystonia, Spasmodic Torticollis
- Trial name
- NCT00210431
- Where
- 36 sites in France, Germany and 1 more
- Volunteers
- 783 people
- Sponsor
- Ipsen
Cervical Dystonia
Comparison of Pallidal With Subthalamic Deep Brain Stimulation for Cervical Dystonia
Cervical dystonia (CD), also known as spasmodic torticollis, is a type of focal dystonia, mainly manifesting as involuntary head turning or tilting, or holding a twisted posture.
- Trial name
- NCT05715138
- Testing
- GPi-DBS, STN-DBS, GPi-DBS devices
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Chinese PLA General Hospital
Dystonia
The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias
Dystonia is a disorder characterized by excessive involuntary contraction of muscles with repetitive and patterned movements. The isolated dystonias are the most common type of dystonia and include Limb dystonias (like writer's…
- Trial name
- DCP (NCT01373424)
- Where
- 42 sites in United States, Australia and 5 more
- Volunteers
- 3,265 people
- Sponsor
- Emory University
Cervical Dystonia
tDCS in Cervical Dystonia
Dystonia is a devastating disorder defined by involuntary, sustained muscle contractions or abnormal postures that can affect any part of the body.
- Trial name
- NCT02180139
- Testing
- transcranial direct current stimulation
- Where
- United States
- Sponsor
- University of Minnesota
Idiopathic Cervical Dystonia
Factors Influencing Response to One BoNT-A Injection Cycle in Subjects Suffering From Idiopathic Cervical Dystonia
A post marketing, international, multicenter, observational, prospective, longitudinal study. The purpose of the study is to describe cervical dystonia sub-types with their injection protocols and response to BoNT-A.
- Trial name
- NCT00833196
- Where
- 39 sites in Australia, Belgium and 7 more
- Volunteers
- 404 people
- Sponsor
- Ipsen
Cervical Dystonia,Primary
A Multimodal Approach to Cervical Dystonia Treatment With Association of Botulinum Toxin and Motor Learning Techniques
the aim of this study protocol is to describe, using a longitudinal study, a multimodal approach of treatment of cervical dystonia with botulinum toxin (BoNTA) and a new rehabilitation protocol named SPRInt (Sensory-motor…
- Trial name
- SPRInt (NCT03247868)
- Testing
- Botulinum Toxin+SPRInt
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cervical Dystonia
Efficacy of Dronabinol for the Treatment of Cervical Dystonia
Cervical dystonia (CD) is characterized by abnormal, involuntary sustained cervical muscles contractions associated with twisting movements and abnormal postures of the neck that can be quite disabling.
- Trial name
- NCT00418925
- Testing
- Dronabinol
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University Health Network, Toronto
Cervical Dystonia, Blepharospasm
Trial Evaluating Xeomin® (incobotulinumtoxinA) for Cervical Dystonia or Blepharospasm in the United States
This is a prospective, observational trial evaluating the "real world" use of Xeomin®(incobotulinumtoxinA). Physicians may enroll patients who are eligible to be treated with a botulinum toxin for cervical dystonia or…
- Trial name
- XCiDaBLE (NCT01287247)
- Testing
- Xeomin®
- Where
- 70 sites in United States
- Volunteers
- 688 people
- Sponsor
- Merz North America, Inc.
Parkinson's Disease, Movement Disorders
Imaging Blood Brain Imaging Dysfunction in Parkinson's Disease
The purpose of this study is to evaluate the blood brain barrier in the striatum of patients that have other types of movement disorders compared to patients with Parkinson's Disease that are receiving similar treatment, to…
- Trial name
- NCT02605161
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Ottawa Hospital Research Institute
Cervical Dystonia
Double-blind, Multicenter Study to Assess the Efficacy of Bilateral Pallidal Stimulation in Patients With Medically Refractory Primary Cervical Dystonia
The purpose of this study is to investigate the efficacy and safety of bilateral pallidal stimulation in patients with medically refractory primary cervical dystonia.
- Trial name
- NCT00148889
- Testing
- Deep brain stimulation (DBS)
- Where
- 10 sites in Austria, Germany
- Volunteers
- 63 people
- Sponsor
- German Parkinson Study Group (GPS)
Cervical Dystonia
Insights Into Deep Brain Stimulation (DBS) for Cervical Dystonia
The purpose of this research study is to determine the physical brain changes in people with cervical dystonia after deep brain stimulation (DBS) surgery and as compared to healthy controls.
- Trial name
- NCT01671527
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Florida
Spasmodic Torticollis
Efficacy and Safety of Two Different Botulinum Toxin Type A Treatments for Moderate to Severe Cervical Dystonia
The purpose of this study is to compare two types of botulinum toxin type A to treat the involuntary muscle contractions in the neck
- Trial name
- NCT00432341
- Testing
- botulinum toxin type A
- Where
- 3 sites in Argentina, Australia and 1 more
- Volunteers
- 54 people
- Sponsor
- Allergan
Cervical Dystonia
Safety and Effectiveness of Valbenazine as Adjunct Therapy to Botulinum Toxin Injections in Cervical Dystonia
The most common form of idiopathic dystonia is adult-onset cervical dystonia (CD), a focal form of dystonia affecting the muscles of the neck.
- Trial name
- NCT06771323
- Testing
- Valbenazine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Primary Cervical Dystonia
Segmental Muscle Vibration on Pain in Patients With Primary Cervical Dystonia
This pilot study aims to evaluate the effectiveness of Vibration Muscle Stimulation (VMS) in reducing pain and improving quality of life in patients with primary cervical dystonia (CD), a focal dystonia characterized by…
- Trial name
- VIBRA-DYSTONIA (NCT06748846)
- Testing
- Physiotherapy + Occupational therapy + Focal Muscle Vibration
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Dystonia, Cervical
Exercise Program for Patients With Cervical Dystonia Who Are Treated With Botulinum Toxin Type A
Dystonia is involuntary movements characterized by posture abnormalities or repetitive movements as a result of continuous or intermittent simultaneous contraction of opposing muscle groups.
- Trial name
- NCT05502718
- Testing
- Stretching and Strengthening Exercises, Breathing and Rhythmic Coordination Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Prof. Dr. Şehim Kutlay
Cervical Dystonia
Daily Dystonia Practice - A Trial to Investigate NT 201, the Duration of Treatment Effect After One Injection Session and in Long-term Treatment in Cervical Dystonia
The aim of this study is to confirm efficacy and safety of NT 201 (Xeomin®, also known as IncobotulinumtoxinA) after one injection session and to determine the efficacy and safety profile and the duration of treatment effect of…
- Trial name
- NCT00541905
- Testing
- NT 201
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Merz Pharmaceuticals GmbH
Essential Tremor, Cervical Dystonia
Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor
Background: Essential tremor is when a person has tremor, but no other neurological symptoms. Dystonic tremor is when a person also has dystonia. Dystonia is a condition in which muscle contraction causes changes in posture.
- Conditions
- Essential Tremor, Cervical Dystonia, Focal Dystonia
- Trial name
- NCT03041714
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cervical Dystonia
Efficacy and Safety of MEDITOXIN® in Cervical Dystonia
The purpose of this study is to test the hypothesis that the efficacy and safety of Meditoxin® are not inferior to Botox®'s in the treatment of Cervical Dystonia.
- Trial name
- CD Phase III (NCT03905304)
- Testing
- Medytoxin, Botox
- Volunteers
- 152 people
- Sponsor
- Medy-Tox