Clinical trials: Spasmodic Torticollis
Cervical Dystonia Adults ,, Abnormal Head Position and Neck Pain for These 7 Muscle Groups: Splenius,Scalene,Sterno-cleido-mastoid,Levator Scapulae,Semispinalis,Trapezius,and Longissimus.
ASIS for Botox in Cervical Dystonia
Botox acts on nerve endings, yet there are no nerve endings inside the muscle, where they are typically injected. All nerves terminate on the fascia, where ASIS device can precisely deliver Botox by creating that subdermal…
- Trial name
- ASISinCD (NCT02074293)
- Testing
- Gadolinium, Efficacy of Botox intramuscularly at Week 6, Efficacy of Botox intramuscularly at Week 12
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- li nguyen
Cervical Dystonia
Zinc as an Adjunctive Therapy for Cervical Dystonia
The goal of this clinical trial is to evaluate if supplemental zinc can prolong the duration of benefit of botulinum toxin injections in cervical dystonia patients receiving care at the University of Florida.
- Trial name
- NCT07140874
- Testing
- Zinc citrate
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Cervical Dystonia
CD-PROBE: Cervical Dystonia Patient Registry for the Observation of onabotulinumtoxinA Efficacy
This study is an observational trial which will measure the efficacy of onabotulinumtoxinA in treating Cervical Dystonia.
- Trial name
- NCT00836017
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 1,046 people
- Sponsor
- Allergan
Cervical Dystonia
Neurotoxin and Physical Therapy
This study aims to compare Botox injections without Physical Therapy sessions to Botox injections combined with Physical Therapy sessions for treatment of Cervical Dystonia.
- Trial name
- NCT02177617
- Testing
- Botox injection, Physical Therapy, Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Florida
Cervical Dystonia
Efficacy and Safety of DYSPORT® Using 2mL Dilution in Adults With Cervical Dystonia.
The purpose of the protocol is to evaluate the efficacy and safety of Dysport® using 2 mL dilution compared with placebo for the treatment of Cervical Dystonia.
- Trial name
- NCT01753310
- Testing
- Botulinum toxin type A
- Where
- 42 sites in United States
- Volunteers
- 134 people
- Sponsor
- Ipsen
Cervical Dystonia
A Trial of Non-invasive Stimulation in Cervical Dystonia
Cervical dystonia (CD) is a common movement disorder. Despite the optimization of botulinum toxin injection (BoNT-A) parameters including muscle selection and dosing, a significant proportion of patients report low levels of…
- Trial name
- NCT04057911
- Testing
- Active NIBS
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Western University, Canada
Cervical Dystonia, Primary
Effects of Botulinum Toxin on Muscle and Brain Activity
This study will look into the effects of Botulinum Toxin in patients with primary cervical dystonia. The effects will be determined by neck muscle activity measurements and brain function activity measurements.
- Trial name
- NCT02837185
- Testing
- Botulinum Toxin injection, Physiological measures
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cervical Dystonia
Clinical Study of Ingrezza (Valbenazine) for the Treatment of Cervical Dystonia
Study of Ingrezza (Valbenazine) for the treatment of cervical dystonia.
- Trial name
- NCT05157100
- Testing
- Ingrezza Pill
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Orthopedic Foundation
Cervical Dystonia
Dystonia Treatment With Injections Supplemented By Transcranial Magnetic Stimulation
We applied 16 sessions of rTMS over 4 consecutive days for adult patients suffering from cervical dystonia who received botulinum toxin (BoNT) injections on a regular basis.
- Trial name
- D-TWIST (NCT04916444)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Florida
Cervical Dystonia
Post-marketing Surveillance of Administration of Botulinum Toxin Type B(NerBloc)-Investigation of the Clinical Condition and Safety in Patients With Cervical Dystonia
Investigation of the clinical condition and safety in patients with cervical dystonia
- Trial name
- NCT02175693
- Where
- 2 sites in Japan
- Volunteers
- 1,647 people
- Sponsor
- Eisai Co., Ltd.
Cervical Dystonia
Tele-yoga and Dystonia
The purpose of this study is to investigate the effect of yoga delivered remotely on adults with dystonia. This work will have implications related to physical interventions symptom management and quality of life as well as…
- Trial name
- NCT04348669
- Testing
- Tele-yoga
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
Cervical Dystonia
Deep Brain Stimulation to Treat Cervical Dystonia
This study will evaluate the effectiveness of deep brain stimulation (DBS) for treating primary dystonia. Patients with dystonia have muscle spasms that cause uncontrolled twisting and repetitive movement or abnormal postures.
- Trial name
- NCT00132340
- Testing
- Electrodes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cervical Dystonia
Physiotherapy and Botox for Cervical Dystonia: Impact of Sensory Tricks and Brain Imaging Insights
The primary aim of this study is to investigate improvements of dystonia severity in patients with cervical dystonia (CD) with (DYT-trick) and without sensory trick (DYT-no-trick) following 6 weeks of physiotherapy combined with…
- Trial name
- NCT06881147
- Testing
- Multimodal physiotherapy program
- Where
- Italy
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Cervical Dystonia
Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 in Cervical Dystonia
This Open-label Extension trial will evaluate the safety and efficacy of ABP-450 for the treatment of cervical dystonia in adults.
- Trial name
- NCT04871451
- Testing
- ABP-450
- Where
- 20 sites in United States
- Volunteers
- 51 people
- Sponsor
- AEON Biopharma, Inc.
Dystonia, Cervical Dystonia
Novel Stimulation Patterns for the Treatment of Dystonia
Deep brain stimulation (DBS) is an effective surgical therapy for select Dystonia patients who are refractory to medications or who have generalized symptoms (e.g.
- Trial name
- NCT02468843
- Testing
- Biphasic DBS stimulation, Unified Dystonia Rating Scale, Burke-Fahn- Marsden scale
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Florida
Dystonia
Deep Brain Stimulation in Patients With Dystonia
The purpose of this study is to evaluate the safety and effectiveness of deep brain stimulation (DBS) of the subthalamic nucleus (STN)for primary dystonia.
- Trial name
- STN DBS (NCT00773604)
- Testing
- Medtronic implantable deep brain stimulation (DBS) system
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of California, San Francisco
Cervical Dystonia
Integration of the Cervical Proprioceptive Signals in Patients With Cervical Dystonia
The purpose of this study is to compare the cervical muscular force control , taking into account the proprioceptive signals, in patients with and without cervical dystonia.
- Trial name
- STAC2 (NCT02834871)
- Testing
- Electromyogram
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cervical Dystonia
Single Treatment of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-1)
This is a randomized, double-blind, placebo-controlled, parallel group, multi-center trial of two doses of daxibotulinumtoxinA (DAXI) for injection (high-dose; low-dose in adult subjects with isolated (primary) cervical dystonia…
- Trial name
- ASPEN-1 (NCT03608397)
- Testing
- DaxibotulinumtoxinA for injection
- Where
- 75 sites in United States, Austria and 7 more
- Volunteers
- 301 people
- Sponsor
- Revance Therapeutics, Inc.
Cervical Dystonia
Keppra for Cervical Dystonia
The purpose of this study is to evaluate if there is an improved response in CD symptoms when Keppra is used as adjunctive therapy to Botox.
- Trial name
- Keppra (NCT00760318)
- Testing
- Keppra
- Volunteers
- 17 people
- Sponsor
- University of South Florida
Cervical Dystonia
Botox for Cervical Dystonia Following EMG Mapping
The purpose of this study is to determine how to improve treatment of patients with cervical dystonia who have not been helped with standard Botox injections.
- Trial name
- NCT00773253
- Testing
- Botulinum toxin A
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco