Clinical trials: Spatial Memory Disorder
Schizophrenia, Psychotic Disorders
Study To Assess Differential Sensitivity Of 2 Spatial Working Memory Tests In Schizophrenics Treated With Risperidone
To assess the effect of risperidone 2 mg daily (QD) on the differential sensitivity of 2 spatial working memory tests (the GMLT and MDR) in non-agitated, drug-naive patients suffering from first-episode…
- Trial name
- NCT00174200
- Testing
- Risperidone 2 mg
- Where
- 3 sites in Canada, Russia
- Volunteers
- 20 people
- Sponsor
- Pfizer
Traumatic Brain Injury
Non-invasive Deep Brain Stimulation to Improve Spatial Navigation Abilities in Individuals Following Traumatic Brain Injury
Impairments in spatial memory and spatial navigation are commonly reported amongst patients presenting post-traumatic brain injury (TBI).
- Trial name
- NCT07271524
- Testing
- Transcranial electric stimulation
- Where
- 2 sites in Switzerland
- Volunteers
- 25 people
- Sponsor
- Friedhelm Hummel
Spatial Navigation, Navigation, Spatial
Investigating the Effect of Training With a Virtual Reality Driving Simulator
The proposed study aims to investigate the use of a driving simulator in a virtual reality (VR) environment to improve the cognition state and spatial navigation of individuals with mild/moderate memory impairment.
- Conditions
- Spatial Navigation, Navigation, Spatial, Dementia
- Trial name
- NCT04074655
- Testing
- Driving Simulator in a Virtual Reality Environment
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Focal Epilepsy, Temporal Lobe Epilepsy
Spatial Scene Recognition Memory in Epilepsy Surgery
This study investigates the anatomical and physiological basis of spatial scene recognition memory in patients with temporal lobe epilepsy and temporal lobe lesions.
- Conditions
- Focal Epilepsy, Temporal Lobe Epilepsy, Medically Refractory Epilepsy, Memory Disorders
- Trial name
- NCT07580183
- Testing
- Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimaging and Neuropsychological Assessment (Aim I)
- Where
- 2 sites in United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Cognition Disorders, Cognitive Deficits
Smart Autonomous Neuro-Rehabilitation System
Cognitive rehabilitation is defined as a systematic functionally oriented intervention of therapeutic cognitive activities based on the assessment and understanding of patient's brain behavior deficits.
- Trial name
- SANaR (NCT02816008)
- Testing
- Cognitive rehabilitation training with RGS in the clinic, Passive/conventional cognitive training at home.
- Volunteers
- 59 people
- Sponsor
- Universitat Pompeu Fabra
Aging, Aging Problems
Brain Health Virtual Reality Study
The Interventions for Brain Health Virtual Reality Study is a NIH-funded clinical research trial at the University of California San Diego (UCSD) Health under the supervision of the study principal investigator Dr. Judy Pa.
- Conditions
- Aging, Aging Problems, Memory Loss, Memory Impairment
- Trial name
- NCT06124339
- Testing
- Physical Activity, Cognitive Activity (VR), Physical and Cognitive Activity
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Parkinson's Disease, Parkinsonism
VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and Parkinsonism
VISMEMO-PD is an observational pilot study aimed at investigating visuospatial memory in reaching space and topographical memory in navigational space in patients with Parkinson's disease and Parkinsonism.
- Conditions
- Parkinson's Disease, Parkinsonism, Multiple System Atrophy, Progressive Supranuclear Palsy
- Trial name
- VISMEMO-PD (NCT07827963)
- Testing
- Multimodal visuospatial and topographical memory assessment
- Where
- 3 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Schizophrenia
A Study to Evaluate the Effects of Once Daily Doses of AQW051 on Cognition, in Stable Schizophrenia Patients
This is a study in chronic stable Schizophrenia with the purpose to answer the question of whether agonism of the nicotinic alpha7 receptor is capable of enhancing cognition in a well defined chronic stable patient population…
- Trial name
- NCT01730768
- Testing
- AQW051
- Where
- 13 sites in United States
- Volunteers
- 147 people
- Sponsor
- Novartis Pharmaceuticals
Age-Related Memory Disorders
An Examination of Visual Perceptual Training
Perceptual-cognitive training (PCT) is a computerized software game has been shown to improve sport performance in young elite athletes and even to aid in recovery speeds post-concussion.
- Trial name
- NCT03763344
- Testing
- Perceptual Cognitive Training (PCT)
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Victoria
Blindness, Blindness, Acquired
Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment
One of the most challenging tasks for blind and visually impaired individuals is navigation through a complex environment. The goal of the present multidisciplinary study is to increase spatial-cognition abilities in people who…
- Conditions
- Blindness, Blindness, Acquired, Low Vision, Blindness, Complete
- Trial name
- NCT05377853
- Testing
- Cognitive-Kinesthetic Navigational Training
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Smith-Kettlewell Eye Research Institute
Alzheimer Disease, MCI
Detecting Dementia Earlier
Aims 1. To determine whether the 4 Mountains test of allocentric (i.e. viewpoint-independent) spatial memory, and tests of memory for a recent experience (e.g.
- Conditions
- Alzheimer Disease, MCI, Aging
- Trial name
- DDE (NCT03900936)
- Testing
- Neuropsychological tests
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Aging, Anxiety
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
Two hallmarks of both healthy aging and age-related disease are 1) memory and navigational deficits, particularly in orienting towards goal locations and planning how to navigate to them, and 2) increased susceptibility to stress…
- Conditions
- Aging, Anxiety, Memory Impairment
- Trial name
- NCT03896529
- Testing
- Anticipatory psychological stress
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Epilepsy Lobe Temporal, Healthy
Spatial Memory and Temporal Lobe Epilepsy
Temporal lobe epilepsy (TLE) can cause memory disorders, including long-term forgetfulness due to a failure to consolidate verbal but also spatial information.
- Conditions
- Epilepsy Lobe Temporal, Healthy, Epilepsy
- Trial name
- EPINAVIG (NCT06847152)
- Testing
- spatial memory test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Class I Malocclusion, Crowded Teeth
The Predictability of Directly Printed Versus Thermoformed Clear Aligners
The study is randomized controlled trial ...The null hypothesis suggests that there is no significant difference between actual and predicted dental movement in patients treated using direct printed aligners produced with Graphy™…
- Conditions
- Class I Malocclusion, Crowded Teeth, Spacing of Anterior Teeth, Rotation
- Trial name
- NCT07350343
- Testing
- Direct-printed aligner (Graphy), Thermoformed aligner
- Where
- Iraq
- Volunteers
- 36 people
- Sponsor
- University of Baghdad
Spatial Memory Disorder
Sevoflurane General Anesthetic and Spatial Memory in Humans
The goal of this observational study is to learn about the effect of general anesthetic on spatial memory in adults who will undergo to an elective surgery.
- Trial name
- NCT05991817
- Testing
- Surgery/general anesthesia
- Where
- 2 sites in Chile
- Volunteers
- 22 people
- Sponsor
- University of Chile
Hemispatial Neglect
Rehabilitating Unilateral Neglect Using Spatial Working Memory Training
Purpose: Stroke is a common cause of death and disability in Canada. Injury to the right hemisphere of the brain and the parietal cortex in particular, is common and results in a disorder known as 'neglect' in 40% to 95% of…
- Trial name
- NCT02608190
- Testing
- Working memory training
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Hearing Loss, Sensorineural
Hearing Aid Processing and Working Memory in Realistic Spatial Conditions
The goal of this project is to determine whether the selection of hearing aid settings should be based in part on an individual's cognitive characteristics (specifically, working memory).
- Trial name
- DIRWDRCWM (NCT04521166)
- Testing
- Hearing aid
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Northwestern University
Schizophrenia
The Effect of Nitric Oxide on Spatial Working Memory in Patients With Schizophrenia - Pilot Study
Spatial working memory (ability to remember where objects are in space) is impaired in patients with schizophrenia. It is thought that this impairment occurs due to problems with the chemical messenger (neurotransmitter)…
- Trial name
- NCT02176044
- Testing
- Sodium Nitroprusside infusion
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- King's College London
Anxiety
Pilot Study of the Impact of Exercise on Hippocampal Function
The goal of this pilot study is to test the procedural aspects of the behavioral tests and the exercise components of the study.
- Trial name
- NCT03036371
- Testing
- High Intensity Interval Exercise
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- New York State Psychiatric Institute
Mild Cognitive Impairment
Spatial Memory Training and Cognitive Function
Mild cognitive impairment (MCI) is often considered a transitional stage between normal aging and dementia, particularly Alzheimer's disease (AD).
- Trial name
- NCT07002996
- Testing
- SMIP, No intervention
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Douglas Mental Health University Institute