Clinical trials: Spatial Neglect, open to volunteers
Stroke, Ischemic Stroke
Robotic rEhabilitation sCenario fOr patieNts With NeglECT
The goal of this pilot clinical trial is to develop an integrated motor and cognitive rehabilitation program and evaluate the usability and acceptability of a new virtual reality scenario designed for the MOTORE device.
- Conditions
- Stroke, Ischemic Stroke, Haemorrhagic Stroke, Neglect, Hemispatial
- Trial name
- RECONNECT (NCT06890481)
- Testing
- Upper-limb planar robotic intervention
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Unilateral Spatial Neglect (USN)
Rehabilitation Methods for Unilateral Spatial Neglect in Stroke Patients
Stroke remains one of the leading causes of mortality and disability worldwide. Between 30% and 40% of patients who have had an acute cerebral hemorrhage, develop unilateral spatial neglect syndrome (USN).
- Trial name
- NCT06802159
- Testing
- Conventional therapy, Eye tracking based therapy, Cognitive therapy
- Where
- 2 sites in Russia
- Volunteers
- 30 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Segmental Exclusion Syndrome, Complex Regional Pain Syndrome (CRPS)
Peripersonal Space Representation in Upper Limb Segmental Exclusion
This study aims to evaluate the representation of action peripersonal space (PPS) in subjects suffering from unilateral segmental exclusion syndrome of the upper limb compared to healthy control subjects.
- Conditions
- Segmental Exclusion Syndrome, Complex Regional Pain Syndrome (CRPS), Upper Limb Neglect (Peripheral)
- Trial name
- NCT07349173
- Testing
- Reachability Judgment Task in VR.
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Stroke, Unilateral Spatial Neglect
Immersive Virtual Reality Treatment for Unilateral Spatial Neglect
Unilateral Spatial Neglect (USN) is a relatively common neuropsychological syndrome following stroke. It is characterized by difficulties in detecting, orienting and identifying events located in the hemispace contralateral to a…
- Trial name
- NCT06366360
- Testing
- Immersive Virtual Reality Intervention, Conventional rehabilitation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hopitaux de Saint-Maurice
Spatial Neglect
Engaging Mobile Prism Adaptation Treatment at Home
Spatial neglect is a common disorder after stroke which leads to problems with noticing or responding to information from the left side of the body or space.
- Trial name
- EMPATH (NCT05595668)
- Testing
- Prism Adaptation - 15-degree prism goggles, Prism Adaptation - 5-degree prism goggles
- Where
- 4 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Perceptual Disorders, Healthy Volunteers
Standardization of Spatial Neglect Assessment Tests
Spatial neglect is a common cognitive disorder in stroke patients, characterized by a lateralized deficit in attention and intention. This research focuses on defining norms for tests to assess spatial neglect.
- Conditions
- Perceptual Disorders, Healthy Volunteers, Reference Values
- Trial name
- NOTEN (NCT07145970)
- Testing
- Neuropsychological assessment tests for spatial neglect
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Unilateral Spatial Neglect, Stroke
Comparing Prism Adaptation Training With and Without TENS to Minimize Unilateral Spatial Neglect
This study aims to find out if doing two treatments together-Prism Adaptation Therapy (PAT) and Transcutaneous Electrical Nerve Stimulation (TENS)-will help people who have had a stroke pay better attention to one side of their…
- Trial name
- NCT07157865
- Testing
- Prism adaptation training combined with TENS, PAT only
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Kettering Health Network
Stroke
Effect of Optokinetic Stimulation on Spatial Neglect and Postural Stability in Patients With Stroke
The purpose of this study is to investigate the efficacy of optokinetic stimulation in stroke patients by examining its effects on spatial neglect, static balance, dynamic balance, and weight-bearing symmetry.
- Trial name
- NCT07424105
- Testing
- Optokinetic stimulation, Traditional therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Stroke, Anosognosia
Improving Awareness for Spatial Neglect With tDCS
Brain-damaged patients can show severe neurological and cognitive deficits, and yet often remain strikingly unaware of these symptoms: this condition is called anosognosia.
- Conditions
- Stroke, Anosognosia, Neglect, Hemispatial
- Trial name
- ANOSO (NCT04845529)
- Testing
- transcranial direct current stimulation (tDCS)
- Volunteers
- 12 people
- Sponsor
- University of Geneva, Switzerland
Stroke, Spatial Neglect
Validation of Web-Based Star Cancellation and Line Bisection Tests in Hemiplegic Stroke
The goal of this observational study is to evaluate the clinical usability and diagnostic performance of newly developed web-based Star Cancellation and Line Bisection tests in assessing visuospatial neglect in hemiplegic stroke…
- Conditions
- Stroke, Spatial Neglect, Spatial Neglect After Stroke
- Trial name
- NCT07538076
- Testing
- Web-Based Star Cancellation Test, Web-Based Line Bisection Test
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Spatial Neglect, Stroke
Spatial-Motor Stroke-Rehab Study
The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.
- Trial name
- NCT06053320
- Testing
- Prism adaptation therapy (PAT) + Electrical stimulation (E-stim), Gait Training
- Where
- 3 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Emory University
Spatial Neglect
Dosing and Deployment Trial: A Home-based Optokinetic Treatment
Several interventions exist for remediation of spatial neglect, but they have mixed evidence. Optokinetic stimulation is a bottom-up intervention; in other words, it is a stimulus-driven process, with Level A (strongest)…
- Trial name
- NCT07519317
- Testing
- Optokinetic stimulation
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Duke University
Stroke, Neglect, Hemispatial
Strategy Training for Optimizing Attention for Individuals With Spatial Neglect
It is common for individuals after stroke to have a cognitive perceptual impairment called unilateral spatial neglect (neglect).
- Trial name
- SOAR (NCT07331896)
- Testing
- Strategy Training, Attention Control
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Pittsburgh
Glioma, Parietal Lobe Glioma
Evaluation of the Variation Over Time of Visuospatial Deficit in Patients With Parietal Lobe Glioma
The goal of modern neurooncological surgery is to obtain maximum tumor resection while preserving neurological function. Parietal lobe gliomas often cause attention deficits (hemineglect) that are difficult to differentiate from…
- Conditions
- Glioma, Parietal Lobe Glioma, Visuspatial Deficit, Unilateral Spatial Neglect (USN)
- Trial name
- neGLIO (NCT07286929)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Spatial Neglect After Right Brain Stroke
Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation
After a right brain stroke, >50% of Veterans experience problems with dressing, eating, self-care or steering their wheelchairs because their ability to move, orient, and respond toward the left side is limited: spatial neglect.
- Trial name
- NCT05983185
- Testing
- Prism adaptation therapy
- Where
- 4 sites in United States
- Volunteers
- 244 people
- Sponsor
- VA Office of Research and Development
Neglect, Brain Injured Patients
Tridimensional Robotic Assessment of Neglect in Brain Injured Patients
The goal of this clinical trial is to assess the usability and feasibility of a robotic and virtual reality-based system called NeglectARm 3D for the three-dimensional assessment of unilateral spatial neglect (USN) in patients…
- Conditions
- Neglect, Brain Injured Patients, Stroke, Unilateral Spatial Neglect (USN)
- Trial name
- NEGLECTARM3D (NCT07290218)
- Testing
- Evaluation with a Non-CE-Marked Robotic Device
- Where
- 3 sites in Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Acquired Brain Injury Including Stroke, Unilateral Spatial Neglect (USN)
Immersive Functional Virtual Reality in People With Acquired Brain Injury and Unilateral Spatial Neglect
Unilateral spatial neglect (USN) is a common and highly disabling condition following acquired brain injury (ABI), significantly impairing individuals' ability to perform daily activities and reducing their autonomy.
- Conditions
- Acquired Brain Injury Including Stroke, Unilateral Spatial Neglect (USN), Stroke, Traumatic Brain Injury
- Trial name
- REVINE (NCT07017140)
- Testing
- Immersive Functional Virtual Reality Intervention using a Head-Mounted Display System for Spatial Neglect Rehabilitation
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- University of Vic - Central University of Catalonia