Clinical trials: Spectrum
Placenta Accreta Spectrum
Effectiveness of REBOA in Reducing Blood Loss During Cesarean Section in Patients with PAS
Obstetric hemorrhage is one of the leading causes of maternal mortality and morbidity worldwide. The major risk factors for obstetric hemorrhage include placenta previa and placenta accreta spectrum (PAS) disorders.
- Trial name
- NCT06721182
- Testing
- REBOA
- Volunteers
- 100 people
- Sponsor
- Nazarbayev University
Autism Spectrum Disorder
Effect of ESDM and PCIT-A in Autism Spectrum Disorder
Children with ASD often show disruptive behaviors. However, interventions that were specifically designed to improve these symptoms have not been sufficiently investigated, especially in children with level 1 to level 3 ASD.
- Trial name
- TAFF (NCT04722783)
- Testing
- Parent-Child-Interaction Therapy adapted for children with autism spectrum disorder (PCIT-A), Early Start Denver Model (ESDM) intervention, 1-hour ESDM
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Bruno Rhiner
Autism Spectrum Disorder, Neurodevelopmental Disorders
AIR-B4: Remaking Recess (RR)
The AIRB research team will compare the use and effectiveness of each intervention (Mind the Gap, Remaking Recess and Self Determination Learning Model of Instruction) with and without the addition of our implementation strategy…
- Trial name
- RR (NCT04972838)
- Testing
- Remaking Recess (RR)
- Where
- 3 sites in United States
- Volunteers
- 264 people
- Sponsor
- Health Resources and Services Administration (HRSA)
Autism Spectrum Disorder, Neurodevelopmental Disorders
AIRB-4: Self-Determined Learning Model of Instruction
The AIRB research team will compare the use and effectiveness of each intervention (Mind the Gap, Remaking Recess and Self Determined Learning Model of Instruction) with and without the addition of our implementation strategy…
- Trial name
- SDLMI (NCT04972851)
- Testing
- Self-Determined Learning Model of Instruction (SDLMI)
- Where
- 3 sites in United States
- Volunteers
- 358 people
- Sponsor
- Health Resources and Services Administration (HRSA)
Autism Spectrum Disorder, Sleep Disturbance
Internet-delivered Cognitive Behaviour Therapy for Sleep Problems in ASD
This trial investigates the behavioural effects of Internet-based Cognitive behaviour therapy for insomnia (CBT-I) in adolescents with autism spectrum disorder with sleep problems. This is a randomised controlled trial.
- Conditions
- Autism Spectrum Disorder, Sleep Disturbance, Insomnia
- Trial name
- NCT03624400
- Testing
- Internet-based CBT-I, Internet-based psychoeducation
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Stockholm University
Autism Spectrum Disorder
Incredible Years Program for Parents of Children with Autism
Early intervention for children with Autism Spectrum Disorder (ASD), particularly with parent involvement, is beneficial for both children and their families.
- Trial name
- IY-ASD (NCT03300128)
- Testing
- Incredible Years - ASD, Circle of Parents
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Autism Spectrum Disorder, Healthy
Effects of Drugs on Responses to Brain and Emotional Processes
To study the effects of a psychostimulant on responses to affective touch in individuals with a range of autistic traits
- Trial name
- MAT (NCT04053036)
- Testing
- MDMA
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Autism Spectrum Disorder
Assessing the Effectiveness of Reciprocal Imitation Teaching in Part C Early Intervention Settings (Sprout Study)
Despite strong consensus that early, specialized intervention for children with Autism Spectrum Disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05425277
- Testing
- Reciprocal Intervention Teaching (RIT), Daily Routines
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Washington
Autism Spectrum Disorder
Treatment Planning for ABA Employing Auxiliary Tools V2+ (TREAAT2+)
Technology enhancement in Applied Behavior Analysis (ABA) treatment planning may increase confidence, efficiency, consistency, and satisfaction for Board Certified Behavior Analysts (BCBAs) which, in turn, can provide for better…
- Trial name
- TREAAT2+ (NCT06204536)
- Testing
- Tech-enabled ABA treatment planning
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Montera Health Texas LLC
Neuromyelitis Optica Spectrum Disorders
A Study to Evaluate the Efficacy and Safety of JYP0061 in Patients With Acute Neuromyelitis Spectrum Disease (NMOSD)
The goal of this clinical trial is to evaluate the efficacy and safety, of JYP0061 in acute NMOSD patients. The main questions it aims to answer are: efficacy and safety of JYP0061 in acute NMOSD patients.
- Trial name
- NCT06697535
- Testing
- JYP0061, Intravenous Glucocorticoids, Oral Glucocorticoids
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Guangzhou JOYO Pharma Co., Ltd
Equine-assisted Therapy, Children
Impact of Equine-Assisted Therapy on the Quality of Life of Children with Autism Spectrum Disorders (ASD)
The main objective of this research is to measure the influence of equine-assisted therapy sessions on the quality of life of children with ASD, using the PedsQL™ 4.0 questionnaire as an evaluation tool.
- Conditions
- Equine-assisted Therapy, Children, Autism Spectrum Disorder, Quality of Lifte
- Trial name
- EQUI-TSA (NCT06698068)
- Testing
- Equine-assisted therapy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hopital La Musse
Autism Spectrum Disorder, Parent-Training
Clinical Efficacy of Cooperative Parent-Mediated Therapy (C-PMT_in_ASD)
The research highlights the lack of studies assessing the effectiveness of evidence-based interventions for ASD in community services.
- Trial name
- C-PMT in ASD (NCT06692946)
- Testing
- Cooperative Parent-Mediated therapy, Treatement as Usual
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- ALESSANDRA CARTA
Physical Inactivity, Cerebral Palsy
Effects of Physical Activity on Prescription (PAP) as a Health-enhancing Intervention in People With Disabilities
Physical inactivity is an increasing problem in the general population in society. However, in people with disabilities, inactivity is even more frequently reported.
- Conditions
- Physical Inactivity, Cerebral Palsy, Autism, Autism Spectrum Disorder
- Trial name
- PAP (NCT05867940)
- Testing
- Physical activity on prescription
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Skane
Autism Spectrum Disorder
Safety, Tolerability and Pharmacokinetics Study of STP1 in a Subgroup of Patients With Autism Spectrum Disorder (ASD)
The main purpose of this study is to evaluate safety and tolerability in a subgroup of patients with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04644003
- Testing
- STP1
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stalicla SA
Autism Spectrum Disorder, Depression
Group Depression Treatment for Autistic Youth
Higher rates of depression are reported by autistic adolescents as compared to their non-autistic peers, which is problematic given adverse outcomes (e.g., negative self-esteem, lower academic performance) that are associated…
- Conditions
- Autism Spectrum Disorder, Depression, Suicidal Ideation, Self Esteem
- Trial name
- NCT05430022
- Testing
- Autism-adapted Group Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University Medical Center
Irritability Associated With Autism Spectrum Disorder, Autism Spectrum Disorder
A Study of JZP541 in Adults With Irritability Associated With Autism Spectrum Disorder
Behavior dysregulation is commonly associated with people with autism spectrum disorder (ASD). Irritability is a major safety concern in adults with ASD.
- Conditions
- Irritability Associated With Autism Spectrum Disorder, Autism Spectrum Disorder, ASD
- Trial name
- NCT05733390
- Testing
- JZP541
- Where
- United States
- Sponsor
- Jazz Pharmaceuticals
Fragile X Syndrome (FXS), Autism Spectrum Disorder
Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder
Fragile X Syndrome (FXS) is a rare genetic syndrome, caused by a mutation in the FMR1 gene located on the X chromosome. It is considered the leading hereditary cause of intellectual disability (ID) and the primary cause of Autism…
- Trial name
- NCT06677866
- Testing
- Cognitive behavioral therapy, Waiting List
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Neuromyelitis Optica Spectrum Disorders
Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE)
The goal of this clinical trial is to study the efficacy and safety of BCD-132 (divozilimab) in subjects with neuromyelitis optica spectrum disorders (NMOSD).
- Trial name
- AQUARELLE (NCT05730699)
- Testing
- divozilimab
- Where
- 19 sites in Russia
- Volunteers
- 105 people
- Sponsor
- Biocad
Autism Spectrum Disorder
The Effect of Simulation-based Training on Confidence and Competence in Obtaining Vitals in a Child With Autism
The objective is to evaluate the efficacy of an online learning module combined with high fidelity simulation-based training in improving medical assistants' and registered nurses' self-confidence and competence scores in taking…
- Trial name
- NCT05288868
- Testing
- Educational Intervention: online didactic lecture and educational simulation activity
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Autism Spectrum Disorder
Effects of Muscle Energy Technique With and Without Stationary Cycling on Toe Walking With ASD
In Autism spectrum disorder (ASD) is a developmental disability caused by differences in the brain. People with ASD often have problems with social communication and interaction, and restricted or repetitive behaviors or…
- Trial name
- NCT06673732
- Testing
- Muscle Energy Technique with Stationary Bi-Cyclying, Muscle Energy Technique without Stationary Cycling
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University