Clinical trials: Speech and Language Disorder
Wisconsin Alzheimer's Disease Research Center, Wisconsin Registry for Alzheimer's Prevention
Speech Pattern Evaluation and Analysis for Knowledge of AD
The goal of this observational study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer's disease and related dementias (ADRD).
- Trial name
- SPEAK-AD (NCT06230783)
- Testing
- TalkTracker
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Mild Cognitive Impairment, Dementia
Short-term Automated Longitudinal Analysis of Speech and Language in Cognitive Impairment
Validate speech analysis AI models: To contrast the accuracy of acceXible's platform as a screening tool in the detection of people with cognitive impairment and mild dementia.
- Trial name
- NCT05340218
- Testing
- Speech analysis
- Where
- Spain
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Accexible
Dyslexia
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study
Developmental dyslexia is a highly heritable disorder in which reading skills are compromised despite normal intelligence and appropriate reading instruction.
- Trial name
- SMeDy (NCT02622360)
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Alzheimer's Disease (AD), Frontotemporal Dementia (FTD)
Automated Language Analysis in Neurodegenerative Diseases: Application of Artificial Intelligence Models
This multicenter study aims to characterize the language profiles of patients with various neurodegenerative diseases, including Alzheimer's disease (AD), Primary Progressive Aphasia (PPA), behavioral variant Frontotemporal…
- Conditions
- Alzheimer's Disease (AD), Frontotemporal Dementia (FTD), Parkinsons Disease (PD), Lewy Body Dementia
- Trial name
- AILAN (NCT07906769)
- Testing
- Speech and language Test to support clinical diagnosis
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Cochlear Implants, Child Language
The Relationship Between Phonological Awareness Skills And Home Environment Literacy in Cochlear Implant Users
The aim was to examine the relationship between home literacy of parents whose has children who use cohlear implant and family demographic characteristics and phonological awareness skills of children with cochlear implant.
- Conditions
- Cochlear Implants, Child Language, Literacy, Phonological (Speech) Disorder
- Trial name
- NCT06322472
- Testing
- The Turkish Early Language Development Test (TEDIL), The Family Literacy Scale, The Early Childhood Phonological Sensitivity Scale (PASECP)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Speech Disorders, Voice Disorders
Personal Protective Equipment Effects
Severe acute respiratory syndrome coronavirus-2 transmits through droplets; thus, oral, nasal, and conjunctival mucosas are related to contamination, and wearing personal protective equipment (PPE) is strongly suggested.
- Trial name
- NCT05369663
- Testing
- mask use
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Parkinson Disease, Multiple System Atrophy
Differential Diagnosis Between Parkinson's Disease and Multiple System Atrophy Using Digital Speech Analysis - Part 2
Parkinson's disease (PD) is the second most common neurodegenerative disease. Multiple system atrophy (MSA) is a relentlessly progressing rare neurodegenerative disease of unknown etiology.
- Trial name
- Voice4PD-MSA (NCT05807373)
- Testing
- voice recordings
- Where
- 2 sites in France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Aphasia
Effect of Verb Network Strengthening Treatment (VNeST) on Lexical Retrieval in Aphasia
The purpose of this study is to evaluate the effect of Verb Network Strengthening Treatment (VNeST) on the ability to produce sentences and connected speech in persons with aphasia.
- Trial name
- VNeST (NCT01300624)
- Testing
- Verb Network Strengthening Treatment
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Developmental Stuttering, Evoked Potentials Auditory
Effect of Stuttering Remediation Exercises on Cortical Auditory Evoked Potentials
studying how the cortical auditory evoked potentials differ in children who stutter from who do not stutter and how these potentials change with therapy
- Trial name
- NCT05473572
- Testing
- Fluency shaping exercises
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Alaa Mamdouh
Stuttering, Childhood, Emotion, Expressed
Intensive Stuttering Group Therapy for School-age Children and the Effect of Emotional Reactivity on Therapy Outcomes
The primary objectives of this investigation were two-fold: 1) to investigate whether implementation of individualized desensitization exercises in an intensive stuttering group therapy for school-age children who stutter is…
- Trial name
- NCT03778632
- Testing
- individualized desensitization exercises
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm
Ultrasound Evaluation of Tongue Movements in Speech and Swallowing
This study will assess the use of ultrasound-a test that uses sound waves to produce images-as a diagnostic tool for evaluating speech and swallowing.
- Conditions
- Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm, Pharyngeal Neoplasm, Polymyositis
- Trial name
- NCT00001167
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Language Development Disorders
Perceptual Learning and Memory Consolidation in Adults With and Without LI
This study tests a memory-based account of atypical speech perception in adults with language-based learning disability (also known as developmental language impairment [LI]).
- Trial name
- NCT03609502
- Testing
- behavioral training
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Down Syndrome, Speech and Language Disorder
Building Sentences With Preschoolers Who Use AAC
The focus of this investigation is to compare the effectiveness of the AAC Generative Language Intervention approach to an AAC Standard of Care condition on preschool sentence productions.
- Conditions
- Down Syndrome, Speech and Language Disorder, Speech Disorders in Children, Speech Intelligibility
- Trial name
- NCT03538925
- Testing
- AAC Generative Language Intervention, Standard of Care / Business as Usual
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Healthy Subjects, Stuttering, Developmental
Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter
Stuttering negatively impacts communication and reduces the overall quality of life and well-being of individuals who stutter. This study will provide a strong foundation for developing neural and behavioral interventions for…
- Trial name
- NCT06181149
- Testing
- Delaying speech initiation, Auditory errors and pre-speech auditory modulation, Contributions of the speech premotor cortex to pre-speech auditory modulation
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Primary Progressive Aphasia, Semantic Dementia
Treatment for Speech and Language in Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a progressive neurological disorder that causes a gradual decline in communication ability as a result of selective neurodegeneration of speech and language networks in the brain.
- Conditions
- Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia
- Trial name
- NCT04881617
- Testing
- Lexical Retrieval Training (LRT), Video-Implemented Script Training for Aphasia (VISTA)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Central Auditory Disease, Healthy
Testing a Possible Cause of Reduced Ability of Children to Process Speech in Noise
This study aims to increase our understanding of the difficulty people have recognizing the spoken word, especially in noisy situations.
- Trial name
- NCT00001957
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Developmental Articulation Disorder, Speech Disorder
Characteristics of Idiopathic Familial Speech Disorders
According to studies, speech disorders with unknown causes (idiopathic) affect approximately 5% of the population at some point in their life.
- Conditions
- Developmental Articulation Disorder, Speech Disorder, Stuttering
- Trial name
- NCT00001551
- Where
- 2 sites in United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Aphasia
Effect of Communication Partner Training Program for the Management of Persons With Aphasia
Communication Partner Training (CPT) is an evidence-based intervention that teaches communication partners (e.g., family members, friends, healthcare workers) how to best support conversation and interaction for a person with…
- Trial name
- NCT05225922
- Testing
- Communication Partner Training, Usual Speech and language Therapy
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Aphasia
LEXURE for Post-Stroke Aphasia
This study evaluates the efficacy of digital language rehabilitation using LEXURE for the treatment of post-stroke aphasia. Half of participants will receive structured language training using the LEXURE application, while the…
- Trial name
- NCT07570264
- Testing
- LEXURE, Workbook
- Where
- 12 sites in South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Nunaps Inc
Amyotrophic Lateral Sclerosis, Parkinson Disease
A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria
The goal is to improve the fundamental knowledge about articulatory motor performance in people with Lou Gehrig's disease (also known as ALS) and Parkinson's disease (PD), in order to develop more sensitive assessments for…
- Trial name
- NCT03613038
- Testing
- Phonetic complexity effects on speech motor performance
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia