Clinical trials: Sperm Quality
Male Infertility
A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0
The purpose of this study is to determine if elevations in oxidative stress, as measured by oxidation-reduction potential (ORP), can distinguish between semen samples from men with abnormal semen parameters from those with normal…
- Trial name
- NCT02839447
- Testing
- Diagnostic
- Where
- 6 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aytu BioPharma, Inc.
Poor Semen Quality
Effects of Plant Extracts on Semen Quality
this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality.
- Trial name
- NCT01357044
- Testing
- Extracts of Punica granatum and Alpinia galanga
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Horsens Hospital
Virtual Reality
Erotica by Virtual Reality on Sperm Donors
Objective To study whether erotica by virtual reality (VR) during masturbation influences the quality of sperm donor ejaculates. Hypothesis Erotica by virtual reality improves ejaculate quality.
- Trial name
- NCT05457764
- Testing
- Virtual reality headset
- Where
- 4 sites in Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cryos International
Infertility, Male, Semen Analysis
The Influence of Fit of Underpants Worn on Semen Quality
The goal of this observational study is to investigate the impact of underpants fit among Thai males attending the Infertility Clinic, whether alone or with their spouses.
- Trial name
- NCT06335706
- Testing
- Fit of underpants worn
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Sperm Quality, Obesity
Obesity With Sperm Quality in Men With Fertility Need
This study aims to investigate the impact of different types of obesity on sperm quality. Participants will be divided into three groups: a normal BMI group, an obese group without pudendal fat wrapping the testicles, and an…
- Conditions
- Sperm Quality, Obesity, Sex Hormones, Visceral Fat
- Trial name
- NCT06353880
- Testing
- Participants will be categorized into three groups based on BMI and the presence of pudendal fat deposition.
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Yu xiaowei
Oligospermia, Sperm Count, Low
Creatine and Ubiquinol for Sperm Quality
This randomized controlled double-blind parallel-group interventional trial explores the impact of 8-week creatine supplementation, with or without ubiquinol, on sperm quality biomarkers in normospermic and oligospermic men.
- Trial name
- CRESPAQ10 (NCT06202469)
- Testing
- Supplement 1, Supplement 2
- Where
- Serbia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
in Vitro Fertilization, Ovulation Induction
Trial Comparing Start Stimulation of Recombinant Follicle Stimulating Hormone (rFSH) on Cycle Day 2 Versus Cycle Day 5 in In Vitro Fertilization (IVF)
Background of the study: Milder stimulation protocols have the advantage of being less expensive and more patient-friendly. Moreover, recent evidence suggests that mild stimulation protocols lead to lower embryo aneuploidy rates…
- Trial name
- LITE (NCT00823472)
- Testing
- Mild stimulation
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Male Infertility
Effect of Antioxidant Probiotic Administration on Seminal Quality and Reproductive Outcomes.
The quality of semen plays a fundamental role in correct fertilization and development of normal embryos that result in a live birth. Unfortunately, semen quality has declined during the last decades, and reduced more and more.
- Trial name
- NCT04585984
- Testing
- Experimental - Probiotic
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Fundación IVI
Unrecognized Condition
Male Supplements for Sperm Quality and Aging
This study investigates the effects of a new supplement on sperm quality in men with poor sperm quality. Fifty patients will receive the supplement for three months, followed by semen analysis and assessment of sperm aging and…
- Trial name
- NCT06339996
- Testing
- Male supplement
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Infertility, Male
Selection of Non Apoptotic Human Sperm for in Vitro Fertilization by Using Magnetic Activated Cell Sorting (MACS)
This clinical study has been organised to help improve the embryo quality in couples having high rate of sperm showing apoptotic signs.
- Trial name
- MACS-HS (NCT03988361)
- Testing
- Magnetic Activated Cell Sorting
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Spermatogenesis and Semen Disorders, Infertility, Male
Power Prenatal Supplements for Sperm Quality
Male factor infertility is a leading cause of primary and secondary infertility. Poor sperm quality is defined as having an abnormal semen analysis [WHO 2020 - https://www.who.int/publications/i/item/9789240030787].
- Trial name
- NCT05410782
- Testing
- Power Prenatal for Sperm
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Bird and Be Co Inc
Sperm Parameters in Fertile and Infertile Men
Evaluation of New Semen Collection & Transportation Kit
Examine the effect of overnight transport conditions on sperm parameters on semen samples collected and mailed to Cleveland Clinic Andrology center.
- Trial name
- NCT04536545
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Turtle Health, Inc.
Semen Quality
The Effects of Microgravity on Human Sperm
It has been described that microgravity affects cellular and molecular structures. Cell membrane, cytoskeleton, cytoplasm and nucleus have been found to be sensible to gravitational changes.
- Trial name
- NCT03760783
- Testing
- Parabolic flight
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
Infertility
Adding Insulin to IVF Culture Media Significantly Improve Outcome
Add insulin to a single step culture media for IVF embryo culture from day 0 to day 5/6 of In Vitro culture and detect the the effect upon embryo quality and implantation potential.
- Trial name
- NCT02420171
- Testing
- Adding insulin to In Vitro culture media
- Where
- 2 sites in Egypt
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Ibn Sina Hospital
Psychological Experience in Fertility Treatment, Hypogonadism
Male Experiences With Intra Cytoplasmic Sperm Injection (ICSI) and Reduced Sperm Quality
Several international studies indicate that men with reduced semen quality often feel overlooked in the context of fertility treatment.
- Conditions
- Psychological Experience in Fertility Treatment, Hypogonadism, Testosteron Levels, Quality of Life
- Trial name
- NCT07546435
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Severe Oligoasthenoteratozoospermia, Sperm Quality
PRP Improves Blastocyst Formation in ICSI Cycles
The goal of this clinical trial is to learn if platelet rich plasma (PRP) works to improve embryo development rates and embryo quality in IVF cycles, involving male adult patients with severe sperm disorders.
- Conditions
- Severe Oligoasthenoteratozoospermia, Sperm Quality, Spermatazoa Disorders, Sperm Parameters in Fertile and Infertile Men
- Trial name
- PRP ICSI SOAT (NCT07579858)
- Testing
- Platelet Rich Plasma
- Where
- Indonesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stella Maris Women and Children Hospital