Clinical trials: Spider Phobia
Phobia, Specific
Influence of Valproic Acid on Extinction-based Therapy in Patients With Fear of Spiders.
The purpose of this study is to evaluate whether valproic acid in combination with fear memory reactivation is useful to enhance treatment stability of exposure therapy for specific phobia.
- Trial name
- VALPRO (NCT02789813)
- Testing
- Valproic Acid, Fear reactivation, No fear reactivation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Acrophobia, Arachnophobia
3D Video Virtual Reality Exposure Therapy Study
This study seeks to examine a Virtual Reality Exposure Therapy (VRET) using the 3D Video Virtual Reality (VR) technology for the fear of spiders.
- Trial name
- 3D-VVRET (NCT02584387)
- Testing
- 3D Video Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Specific Phobias
tDCS-Augmented Exposure Therapy for Pathological Fear
This double-blind randomized controlled clinical trial aims to test whether transcranial direct current stimulation (tDCS) can be used to modulate fear extinction learning during exposure therapy for pathological fear, including…
- Trial name
- NCT03095482
- Testing
- Transcranial Direct Current Stimulation (tDCS), In vivo exposure therapy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Specific Phobia
Enhancing Exposure Therapy for Snake and Spider Phobias
This study tests whether exposure therapy for fear of snakes or spiders is enhanced by the addition of a brief fear retrieval trial prior to treatment, and the use of compound extinction during treatment.
- Trial name
- Snake/Spider (NCT02160470)
- Testing
- Exposure Therapy with Retrieval, Exposure Therapy with Compound Extinction, Exposure Therapy with Retrieval and Compound Extinction
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Fear of Spiders
Neural Mechanisms of Imaginal and in Vivo Exposure
Imaginal exposure is a widely used and effective psychological treatment technique. Recent research suggests that neural activations and emotional responses during imaginal exposure are similar to those elicited during in vivo…
- Trial name
- NCT05193383
- Testing
- Imaginal exposure, Exposure, Approach-avoidance conflict
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Phobic Disorders
The Role of Treatment Expectation in Exposure Training With Spider Fearful Participants
This study evaluates the role of treatment success expectation in spider fearful individuals on the actual treatment success. Half of participants will have positive treatment success expectations, while the other half will have…
- Trial name
- NCT03012035
- Testing
- positive treatment expectations, neutral treatment expectations
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Specific Phobia
Spider Phobia Opposite Action Treatment Study
This study tests the effectiveness of exposure therapy for fear of spiders as enhanced by the use of antagonistic or opposite actions during treatment.
- Trial name
- NCT02905279
- Testing
- Biofeedback Relaxation Training, Exposure Therapy, Exposure with Threat-Relevant Opposite Actions
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Phobic Disorders
Neurophysiological Correlates of Exposition Therapy in Spider Phobia
This study aims to investigate the neurophysiological correlates of spider phobia and its treatment with CBT based Exposure Therapy.
- Trial name
- NCT03653923
- Testing
- Exposure Therapy
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Fear of Spiders
The Neural Mechanisms of Imaginal Extinction
Imaginal exposure is a widely used and effective psychological treatment technique in which patients are exposed to fearful stimuli and situations using mental imagery.
- Trial name
- NCT05168592
- Testing
- Threat conditioning, Imaginal extinction
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Individuals With Fear of Spiders
Neural Activations During Imaginal Exposure in Individuals Fearful of Spiders
This study explores the brain basis of imaginal exposure, a widely used psychological treatment technique. Specifically, this study uses functional magnetic resonance imaging to examine brain areas activated during imaginal…
- Trial name
- NCT03969160
- Testing
- Imaginal exposure
- Where
- 2 sites in Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Fear of Spiders
Efficacy of a Gamified Augmented Reality Exposure-based Application in Subjects With Fear of Spiders
Investigation of the efficacy of a gamified augmented reality exposure app in individual with fear of spiders.
- Trial name
- GARET2019 (NCT04162509)
- Testing
- AR app
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Posttraumatic Stress Disorder, Anxiety Disorder
Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
The aim of this project is to create fear conditioning paradigm within which the relative strengths of various novel pharmacological and behavioral interventions can be tested.
- Trial name
- NCT01631682
- Testing
- Propranolol, Reactivation, Mifepristone
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Phobias
fMRI Study Examining Effects of D-cycloserine in Specific Phobia
The research team hopes to use brain imaging and mental testing to learn more about specific phobias and the treatment of phobia.
- Trial name
- NCT00591825
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center