Clinical trials: Spinal
Lumbar Degenerative Disc Disease
Lumbar Degenerative Disc Disease Treated With Anterior Tension Band System (ATB) With ALIF/FRA Spacer
Multi-center, prospective nonrandomized study of treatment for 1 and 2 level degenerative disc disease between L2 and S1. Patients will be followed for a minimum of 2 years.
- Trial name
- ATB (NCT01323387)
- Testing
- Interbody Fusion
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Synthes USA HQ, Inc.
Neck Disability, Back Disability
Chiropractic and Exercise Management of Spinal Dysfunction in Seniors
This study will compare the effectiveness of chiropractic and exercise treatment in the short- and long-term, when managing chronic neck and back disability in seniors over the age of 65 years.
- Trial name
- NCT01057706
- Testing
- chiropractic, exercise
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwestern Health Sciences University
Disc Herniation, Kinesiophobia
The Effectiveness of Pilates in Women With Lumbar Disc Herniation
The aim of the study was to compare the effects of reformer pilates and mat exercise on pain, quality of life and kinesiophobia in female patients with lumbar disc herniation.
- Conditions
- Disc Herniation, Kinesiophobia, Low Back Pain
- Trial name
- NCT07261020
- Testing
- mat pilates, reformer pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Corset, Spinal Mobility
Effects of Different Hyperextension Braces on Spinal Mobility
This project aims to investigate the effects of different hyperextension braces (Jewett and Spinomed) on spinal mobility and posture.
- Conditions
- Corset, Spinal Mobility, Posture
- Trial name
- NCT07170813
- Testing
- Spinal hyperextension brace
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mustafa Tahsin Ozer
Chronic Disease, Arthritis
Deep Dive Randomized Control Trial
Compare two care management support program models on medical costs and utilization.
- Conditions
- Chronic Disease, Arthritis, Uterine Diseases, Spinal Diseases
- Trial name
- NCT00793260
- Testing
- Enhanced Support, Usual-Support
- Where
- United States
- Volunteers
- 174,120 people, healthy volunteers welcome
- Sponsor
- Health Dialog
Neoplasms, Glandular and Epithelial, Diphtheria
Concomitant Use of Gardasil (V501, Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combined Diptheria, Tetanus, Pertussis and Poliomyelitis Vaccine in Adolescents (V501-024)(COMPLETED)
Data from this study are expected to demonstrate that Gardasil (V501, Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine), when administered concomitantly with a combined diphtheria, tetanus, pertussis, and…
- Conditions
- Neoplasms, Glandular and Epithelial, Diphtheria, Tetanus, Whooping Cough
- Trial name
- NCT00337428
- Testing
- Comparator: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant (qHPV) Vaccine from Current Manufacturing Facility (CMF), Comparator: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant (qHPV) Vaccine from Future Manufacturing Facility (FMF), Comparator: REPEVAX™ (Concomitant)
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Discopathy, Herniated Cervical Disc
Post Market Clinical Follow up Study With the Cervical Disc Prothesis MOVE®-C
Study design: International, prospective, multicentre, non-randomised, observational study according to § 23b MPG. Objectives: Observational study to confirm the safety and performance of the cervical disc prosthesis MOVE®-C.
- Conditions
- Discopathy, Herniated Cervical Disc, Stenoses, Spinal, Radiculopathy
- Trial name
- PMCF_MOVE®-C (NCT05035693)
- Testing
- MOVE®-C
- Where
- 7 sites in Austria, Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- NGMedical GmbH
Cervical Spondylosis
A Magnetic Resonance Imaging Study of Patients With Cervical Spondylosis
This study aims at evaluating spinal cord structure using diffusion tensor imaging in patients with cervical spondylosis.
- Trial name
- Tractocervical (NCT01243684)
- Testing
- DTI - Diffusor Tensor Imaging
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cervical Lordosis Rehabilitation
The Efficacy of Cervical Lordosis Rehabilitation for Nerve Root Function and Pain in Cervical Spondylotic Radiculopathy
To test the hypothesis that improvement of cervical lordosis (CL) in cervical spondylotic radiculopathy (CSR) will improve clinical features in a population suffering from CSR.
- Trial name
- NCT05547997
- Testing
- Stretching exercises, Two way traction
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spinal Cord Injury
Respiratory Motor Control and Blood Pressure Regulation After Spinal Cord Injury
The proposed study is designed to answer a novel research question: Can resistive respiratory muscle training designed to improve respiratory motor control also improve blood pressure regulation impaired by spinal cord injury?…
- Trial name
- NCT02396823
- Testing
- Respiratory Muscle Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Spinal Cord Injury
Neuromodulation to Improve Grasping Function After SCI
The goal of this study is to restore the activities of late descending signals with a noninvasive stimulation approach in combination with hand motor training to improve hand function in persons with cervical SCI.
- Trial name
- NCT07433959
- Testing
- iTBS, PCMS, Exercise
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Vaginal Delivery
The Effects of Combined Spinal Epidurals on Fever During Labor of First-Time Mothers
The purpose of this study is to determine if the epidural of local anesthetics has an effect on fever that may occur in first time mothers during labor.
- Trial name
- CSE (NCT00802646)
- Testing
- saline, fentanyl/bupivacaine/epinephrine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Friedreich Ataxia, Cardiomyopathies
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ATI-105 in Healthy Adults
The goal of this clinical trial is to learn how ATI-105 administered to healthy participants at works in the body at different doses and with or without food.
- Conditions
- Friedreich Ataxia, Cardiomyopathies, Central Nervous System Diseases, Neuromuscular Diseases
- Trial name
- NCT07869654
- Testing
- ATI-105
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Adjuvia Therapeutics, Inc.
Axial Spondyloarthritis
Ultrasonographic Evaluation of the Shoulder Joint in Patients With Axial Spondyloarthritis
The aim of this observational study is to assess shoulder joint involvement in patients with axial spondyloarthritis using ultrasound and to compare the findings with those of healthy controls.
- Trial name
- NCT06727266
- Testing
- Shoulder ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Psoriatic Arthritis
DC-STAMP: Regulators of Osteoclastogenesis and Response Marker in PsA
The Investigators will examine if DC-STAMP can serve as an early marker of TNFi response in PsA. Identification of such a biomarker would permit rapid transition to a new agent, a major treatment advance.
- Trial name
- NCT03011242
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Spinal Muscular Atrophy
Newborn Screening for Spinal Muscular Atrophy
To test if the routine newborn screening dried blood spots can be used to test if missing 2 copies of SMN1 gene, a status indicating spinal muscular atrophy
- Trial name
- NCT02123186
- Testing
- newborn screening test for SMA
- Where
- Taiwan
- Volunteers
- 120,267 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Orthopedic Disorder
The Duration of Spinal Anaesthesia - a Prospective, Observational Cohort Study
Today, surgery in an ambulatory setting is preferred for many reasons. Total hip and knee arthroplasty (THA and TKA) are now procedures where patients can be sent home on the same day of the surgical procedure.
- Trial name
- Spinalrocks (NCT06459986)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Spinal Cord Injuries
Analysis of the Motion Activity Manual Wheelchair Users
Currently, there is no system in place to allow manual wheelchair users to know their quantities of movement activities and the intensity of effort to be provided during these propulsion movements.
- Trial name
- Acti-FRM (NCT04285970)
- Testing
- cycle detection, detection of effort intensity
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Neck Pain
The Effects of Spinal Manipulation on Performance on Neck Pain Patients During a Fitts' Task
The objective of this study is to quantify motor performance, this study will use an eye movement Fitts' task to examine the effects of cervical spine manipulation on participants with chronic neck pain and the subsequent changes…
- Trial name
- NCT04347551
- Testing
- High velocity/low amplitude cervical spine manipulation
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
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