Clinical trials: Spinal
Cesarean Section, Post Operative Pain
Ilioinguinal Iliohypogastric Nerve Block as Adjunct to Spinal Anesthesia for Cesarean Section
The aim of the present controlled randomized study is to compare between ilioinguinal/iliohypogastric nerve block (IINB) and morphine as adjuncts to spinal anesthesia for cesarean section regarding quality of post-operative…
- Trial name
- NCT06108895
- Testing
- ilio-inguinal/ilio-hypogastric nerve block (IINB), intrathecal morphine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Immobilization
Time Performance of Scoop Stretcher Versus Vacuum Mattress for Prehospital Spinal Stabilization
A simulation-based randomized controlled trial was designed with the objective to assess the time needed to achieve spinal stabilization using a scoop stretcher compared to a vacuum mattress.
- Trial name
- NCT04904770
- Testing
- Scoop stretcher, Vacuum mattress
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Stuby Loric
SCI - Spinal Cord Injury, Cardiovascular Risk Factor
Cardiovascular Risk Markers in Spinal Cord Injured Subjects of the Wheelchair Dancer Study
The present study will analyze if exercise is able to elicit the well-known anti-atherogenic effects in patients with SCI. This will be evaluated by measuring vascular parameters such as endothelial and inflammatory blood…
- Trial name
- NCT03352505
- Where
- 2 sites in Austria
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Poliomyelitis
A Study to Evaluate the Mucosal Intestinal Immunity to Poliovirus Type-2 of nOPV2 at Birth Dose in Healthy IPV Vaccinated Infants
The study will compare the transmissible levels of poliovirus type-2 detected in stool samples collected at the time of the nOPV2 challenge and subsequent timepoints in 3 groups of newborns receiving an nOPV2 dose at birth and…
- Trial name
- NCT07010822
- Testing
- nOPV2
- Where
- Bangladesh
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- Fidec Corporation
Anesthesia, Cognitive Dysfunction
Evaluation of Cognitive Functions by Cerebral Pulse Oximetry
General and Spinal Anesthesia can be used in geriatric patients in orthopedic surgery. Post-op cognitive dysfunction can be seen in orthopedic surgeries in this group of patients.
- Trial name
- NCT03827083
- Testing
- cerebral pulse oximetry
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Temperature Change, Body, Chills
Does Higher OT Temperature and IV Ondansetron Reduce Incidence of PSS in Parturients?
This study will look at the incidence of post-spinal shivering (PSS) among the obstetrics population and will investigate whether higher operation theater (OT) temperature range or/and IV Ondansetron are able to reduce the…
- Conditions
- Temperature Change, Body, Chills, Tremor, Nausea, Postoperative
- Trial name
- HOTON (NCT04654429)
- Testing
- IV Ondansetron 4mg, Higher OT temperature range, Lower OT temperature Range
- Where
- Malaysia
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Dr Lim Siu Min
Spinal Cord Injuries
Feeding Regulation in SCI
The overall purpose of this research is to understand the reasons why persons with spinal cord injuries eat more calories than they need to "burn", stay alive, and function.
- Trial name
- NCT05406739
- Testing
- Test Meals
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Miami
Scoliosis
The Effect of Schroth Method on Pain, Body Awareness and Quality of Life in Adolescent Individuals With Idiopathic Scoliosis
This study was aimed to compare the effect of Schroth therapy method, which is a 3-dimensional scoliosis exercise method, and traditional exercises on pain, body awareness and quality of life in young individuals with idiopathic…
- Trial name
- NCT04689295
- Testing
- exercise programme 1, exercise programme 2
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hypotension
Norepinephrine To Prevent Hypotension After Spinal Anesthesia For Cesarean Delivery: A Dose Finding Study
Spinal anesthesia is the most common anesthetic technique for elective Cesarean delivery (CD), but the most frequent unwanted side effect is hypotension, which can cause nausea and vomiting, as well as effects on the fetus.
- Trial name
- NCT02654847
- Testing
- Norepinephrine, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Poliomyelitis
An Immunogenicity and Safety Study of Sabin Inactivated Poliovirus Vaccine (Vero Cell) in 2-month-old Infants
The purpose of this phase III study is to evaluate the immunogenicity and safety of Sabin Inactivated Poliovirus Vaccine (Vero cell) in 2-month-old infants.
- Trial name
- NCT03526978
- Testing
- Investigational sIPV, Control IPV
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Spinal Cord Injuries
Protein Supplementation and Neuromuscular Electrical Stimulation in Persons With SCI
The aim of this pilot study is to explore how body composition, circulating markers of metabolic health and skin integrity in persons with a spinal cord injury (SCI) are affected by 12 weeks of quadriceps neuromuscular electrical…
- Trial name
- NCT05249985
- Testing
- NMES, Protein
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Parkinson Disease, Postural Kyphosis, Lumbosacral Region
The Relationship of Trunk Position Sense and Spinal Posture With Balance in Parkinson's
The 4 main motor symptoms seen in Parkinson's patients are tremor, rigidity, postural instability and bradykinesia. In addition to these, another common symptom investigators encounter is balance problems.
- Conditions
- Parkinson Disease, Postural Kyphosis, Lumbosacral Region, Postural Kyphosis, Postural Lordosis, Lumbosacral Region
- Trial name
- NCT05233943
- Testing
- Spinal Mouse and Digital Inclinometer
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Diphtheria, Polio
Safety and Immune Response of Different Pediatric Combination Vaccines.
The overall aim of the study is to corroborate that a schedule consisting of 3 doses of Pentacel™ and a 4th dose of DAPTACEL® and ActHIB® or 4 doses of Pentacel™ or 4 doses of Quadracel and ActHIB® is as safe and immunogenic as a…
- Conditions
- Diphtheria, Polio, Pertussis
- Trial name
- NCT00255047
- Testing
- DAPTACEL®. (DTaP), IPOL®., and ActHIB®., Pentacel®: DTaP-IPV/Hib combined, DTaP-IPV and ActHIB®
- Where
- 36 sites in United States
- Volunteers
- 2,167 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Neck Pain
The Investigation of Thoracic Spinal Curvature and Mobility in Subjects With and Without Neck Pain: Cut-off Points
The purpose of this study is to investigate the sagittal thoracic spinal curvature and mobility in subjects with and without chronic neck pain, cut-off points and pain relationship
- Trial name
- NCT02424058
- Testing
- Spinal Mouse® measurement, Neck pain intensity measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk Training and Research Hospital
Motor Disorders, Healthy
Non-invasive BCI-controlled Assistive Devices
Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibits sensorimotor rhythms (SMRs) during movement intents or motor imagery…
- Conditions
- Motor Disorders, Healthy, Spinal Cord Injuries, Muscular Diseases
- Trial name
- NCT05183152
- Testing
- NMES Feedback, Visual Feedback, TESS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Diphtheria, Tetanus
Safety and Immunogenicity Study of a Diphtheria, Tetanus, Acellular Pertussis and Poliomyelitis Vaccine (REPEVAX) Followed by 2 Doses of a Diphtheria, Tetanus and Poliomyelitis Vaccine (REVAXIS) in Subjects of 40 Years of Age or Older
Primary objective: To demonstrate that 3 doses of a vaccine containing Td-IPV valences administered in a 0, 1 and 6-month schedule induce an acceptable immune response in terms of seroprotection rates (SPR) against diphtheria…
- Conditions
- Diphtheria, Tetanus, Poliomyelitis, Pertussis
- Trial name
- NCT01287949
- Testing
- Diphtheria, tetanus, polio and pertussis vaccination
- Where
- 12 sites in France, Germany
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Virtual Reality
The Effect of Virtual Reality on Patients With Anxiety Over Surgeries Under Spinal Anesthesia
The main purposes of this study are as follows: First, to understand the effect of virtual reality on the subjective feelings of anxiety in patients with orthopaedic lower limb surgery for spinal anesthesia.
- Trial name
- NCT03922009
- Testing
- Virtual Reality
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Amyotrophic Lateral Sclerosis (ALS), Peripheral Neuropathies
Translating Single-cell Vulnerability Into Novel ALS Biomarkers and Therapeutic Targets: Towards a Liquid Nerve Biopsy
The progress of ALS research and clinical practice is hampered by lack of effective biomarkers to monitor disease onset and progression.
- Trial name
- TUNEABLE (NCT07268833)
- Where
- 4 sites in Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
Interactions Between Neurostimulation and Physical Exercise
People with cervical spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS) have reduced connections in the nerve circuits between the brain and the hands.
- Trial name
- NCT03076632
- Testing
- Cervical plus transcranial stimulation, Cervical stimulation plus hand/wrist exercise, Electromyographic (EMG)-triggered (closed-loop) stimulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Traumatic Brain Injury, Cervical Spinal Cord Injury
Restorative Neuromodulation for Upper Extremity Functions
The objective of this research study is to find the efficacy of trans-spinal electrical stimulation, a non-invasive neurostimulation method to modulate the functions of spinal cord neurocircuits, on improving upper-extremity…
- Trial name
- NCT04183998
- Testing
- Trans-spinal Electrical Stimulation (tsES)
- Where
- Hong Kong
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
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