Clinical trials: Spinal
Spinal Fractures
Effect and Essentiality of Vertebroplasty Surgery in Acute Vertebral Compression Fractures
Percutaneous vertebroplasty is now a common procedures of patients with acute osteoporotic vertebral compression fractures in medical units all over China, but the efficacy and essentiality of the surgery remain uncertain and is…
- Trial name
- NCT03360383
- Testing
- percutaneous vertebroplasty, conservative treatment
- Volunteers
- 400 people
- Sponsor
- Peking University People's Hospital
Degenerative Disc Disease, Low Back Pain
Effectiveness and Safety of Mesenchymal Stem Cell (MSC) Implantation on Degenerative Discus Disease Patients
This study evaluates the effectivity and safety of MSC implantation on Degenerative Disc Disease Patients by assessing visual analog scale, ROM improvement and MRI examination.
- Conditions
- Degenerative Disc Disease, Low Back Pain, Disc Degeneration
- Trial name
- MSC (NCT04499105)
- Testing
- Mesenchymal Stem Cell + NaCl 0,9% 2ml
- Where
- Indonesia
- Volunteers
- 10 people
- Sponsor
- Ahmad Jabir Rahyussalim
Spinal Stenosis, Spondylolisthesis
Greenwich Lumbar Stenosis SLIP Study
The purpose of the study is to determine the proper use of lower back screws and rods (instrumentation) and bony fusion in subjects with one level of degenerative spinal narrowing (stenosis) compressing nerves to the legs with…
- Trial name
- SLIP (NCT00109213)
- Testing
- Lumbar Laminectomy with Instrumented Pedicle Screw Fusion, Lumbar Laminectomy
- Where
- 5 sites in United States
- Volunteers
- 66 people
- Sponsor
- Greenwich Hospital
Sensation Diminished, Pinprick
A Device to Determine Return of Sensation From Spinal Block
Participation in this study will involve having a pad wrapped onto the subject's non-surgical leg to detect when sensation returns after spinal anesthetic and while in recovery room.
- Trial name
- NCT04553913
- Testing
- cooling device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Wake Forest University Health Sciences
Pregnancy
Predicting Hypotension Related to Spinal Anesthesia for Caesarean Section With Ultrasonography
Spinal anesthesia is the main technique for caesarean section. This anesthesia is followed by a hypotension in 40% to 90% despite preventing tools. Hypotension is responsible of foetale and maternal suffering.
- Trial name
- NCT02471924
- Testing
- Trans thoraciq cardiac ultrasonography
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Spinal Cord Injury, Spinal Cord Disease
Paired Spinal Cord and Peripheral Nerve Stimulation to Recover Hand Function in SCI
Individuals who suffer a spinal cord injury in the neck region have difficulty using their hands due to paralysis and/or weakness of their arms and hand muscles.
- Conditions
- Spinal Cord Injury, Spinal Cord Disease, Spinal Cord Injuries (SCI)
- Trial name
- NCT06698224
- Testing
- Spinal cord transcutaneous stimulation, Paired spinal cord and peripheral nerve stimulation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Total Joint Arthroplasty
Utility of Indwelling Catheter in Orthopaedic Patients Receiving Spinal Anesthesia
A study measuring utility of indwelling bladder catheter placement in orthopaedic surgical patients receiving spinal anesthesia. Study will track clinical outcomes, patient satisfaction and cost efficacy.
- Trial name
- NCT01577823
- Testing
- Foley Catheter
- Where
- United States
- Sponsor
- Rothman Institute Orthopaedics
Tactile Hyperalgesia, Neuropathic Pain
Effects of Pregabalin on Mechanical Hyperalgesia
The aim of this randomized placebo-controlled study is to evaluate the effects of analgetics for neuropathic pain on mechanical hyperalgesia as a kind of evoked pain.
- Trial name
- NCT00310583
- Testing
- Pregabalin
- Where
- 17 sites in Germany
- Volunteers
- 120 people
- Sponsor
- Professional Associations Clinic Bergmannsheil
Neuromodulatory Effects of TSCS and FES in Lower Limbs
Ultrasound for Quantifying Muscle Activation Elicited by Spinal Cord Stimulation and Functional Electrical Stimulation
Transcutaneous (non-invasive) spinal cord stimulation (tSCS) has been shown to facilitate volitional motor activity in patients with spinal cord injury.
- Trial name
- NCT07206797
- Testing
- Functional Electrical Stimulation, Transcutaneous (Non-Invasive) Spinal Cord Stimulation, Ultrasound
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Spine Deformity
Novel Pedicle Screws Used for Corrective Surgery in Spinal Deformity
There are still a large number of severe spinal deformity cases which would keep progressing without treatment. These patients not only have severe appearance deformity, but also suffer from cardiopulmonary compression, reduced…
- Trial name
- NCT06144879
- Testing
- double rods without dual-headed screw, three rods with one dual-headed screw, four rods with two dual-headed screw
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Spinal Anesthesia
Chloroprocaine for Inguinal Herniorrhaphy
This study is to determine the minimum effective dose for intrathecal chloroprocaine in inguinal herniorrhaphy in outpatients using a Combined Spinal Epidural (CSE) anesthesia.
- Trial name
- NCT03805503
- Testing
- Chloroprocaine 1% Injectable Solution
- Volunteers
- 12 people
- Sponsor
- University Hospital, Ghent
Post-Dural Puncture Headache, Headache After Spinal Puncture
Comparison of Post-Dural Puncture Headache After Spinal Anesthesia Using Median Versus Paramedian Approach
This randomized controlled trial will compare two commonly used techniques for performing spinal anesthesia, the median (midline) approach and the paramedian (lateral) approach, in adult patients undergoing elective orthopedic or…
- Trial name
- NCT07436403
- Testing
- Spinal anesthesia using median approach (midline), Spinal anesthesia using paramedian approach
- Where
- Pakistan
- Volunteers
- 142 people
- Sponsor
- Mayo Hospital Lahore
Psoriatic Arthritis
Safety and Efficacy of Tofacitinib vs Methotrexate in the Treatment of Psoriatic Arthritis
Title Safety and Efficacy of Tofacitinib vs Methotrexate in the treatment of Psoriatic Arthritis- An Open Label Randomized single center study Psoriatic arthritis is defined as an inflammatory arthropathy associated with skin…
- Trial name
- PsOLSET-BD (NCT03736161)
- Testing
- Group A- Tofacitinib, Group B- Methotrexate
- Where
- Bangladesh
- Volunteers
- 61 people
- Sponsor
- Globe Pharmaceuticals Limited
Secondary Osteoporosis, Spinal Cord Injury
The Efficacy of Denosumab in Incomplete Patients Spinal Cord Injury
The purpose of this study is to determine the usefulness of a drug, denosumab, to prevent the loss of bone in participants legs due to SCI.
- Trial name
- NCT03029442
- Testing
- Denosumab (Prolia)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Cerebral Autoregulation
Feasibility of Using NeuraSignal Transcranial Doppler Robot
The purpose of this study is to determine the feasibility of using the NeuraSignal transcranial doppler robot in a neuro ICU setting to measure cerebral blood flow correlated with arterial blood pressure to generate…
- Trial name
- NCT06565442
- Testing
- NeuraSignal transcranial doppler robot
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Spinal Tumors
Stereotactic Body Radiation Therapy (SBRT) for Tumors Near the Spinal Cord
The purpose of this research study is to determine if Stereotactic Body Radiation Therapy (SBRT) is a good way to treat tumors near the spinal cord.
- Trial name
- NCT00631670
- Testing
- Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Florida
Post-polio Syndrome, Physical Activity
Glutathione and Health With Post-Polio Syndrome
In this study, people who have symptoms of post polio will take oral glutathione supplements for three months. Their levels of fatigue, physical activity and sleep efficiency will be assessed.
- Conditions
- Post-polio Syndrome, Physical Activity, Depression, Pain
- Trial name
- NCT01402570
- Testing
- Glutathione
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Androgenetic Alopecia
Association of Polymorphisms in the Androgen Receptor Gene and Finasteride Response in Women With Androgenetic Alopecia
Previous studies of finasteride treatment in women with hair loss have failed to show positive results, yet, some women have responded anecdotally.
- Trial name
- NCT01052870
- Testing
- Finasteride
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- HairDx, LLC
Laminectomy, Post-laminectomy Syndrome
Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Traditionally, pain relief through spinal cord stimulation has been associated with the appearance of paresthesia in the affected area.
- Conditions
- Laminectomy, Post-laminectomy Syndrome, Spinal Cord Syndrome, Failed Back Surgery Syndrome
- Trial name
- NCT03702010
- Testing
- spinal cord stimulation conventional, spinal cord stimulation experimental
- Where
- 2 sites in Spain
- Volunteers
- 27 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Spondylolisthesis, Spinal Stenosis
Prospective Follow-up of Elderly Patients Undergoing Instrumented Lumbar Arthrodesis Supplemented by the Implanet Jazz System(TM)
Establish a data repository of patients who have undergone single, two-, or three-level lumbar instrumented arthrodesis procedures supplemented by the Implanet Jazz System.
- Conditions
- Spondylolisthesis, Spinal Stenosis, Degenerative Disease
- Trial name
- NCT03434223
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Ohio State University
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