Clinical trials: Spinal Anesthesia
Operation
Spinal Anesthesia Magnesium Infusion
The aim of this study was to investigate the effect of i.v. infusion of magnesium sulphate during spinal anesthesia on duration of spinal block and postoperative pain.
- Trial name
- NCT02011152
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy, Aspiration
The Effect of Low-Dose vs High-Dose Epidural Fentanyl on Gastric Emptying - A Prospective Double-Blinded Randomized Controlled Trial
This study investigates the effect of epidural fentanyl on gastric emptying in non-fasted laboring women. Half the women will be randomized to receive low-dose epidural fentanyl (<100 mcg), and half will be randomized to receive…
- Trial name
- NCT04202887
- Testing
- Low Dose Fentanyl, High Dose Fentanyl, Gastric Ultrasonography
- Where
- Israel
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cesarean Birth, Spinal Anesthesia
Dexmedetomidine Versus Ketamine Loading for Dexmedetomidine Sedation During Elective Cesarean Section Under Spinal Anesthesia
This is a prospective, randomized, double-blind clinical study designed to compare the maternal and early neonatal effects of a loading dose of dexmedetomidine versus low-dose ketamine in parturients undergoing elective cesarean…
- Conditions
- Cesarean Birth, Spinal Anesthesia, Sedation
- Trial name
- Sedation (NCT07676955)
- Testing
- Dexmedetomidine, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Lower Extremity Problem, Gynecologic Disease
Comparison of the Effect of Remimazolam and Propofol on Perioperative Hypothermia Under Spinal Anesthesia
After dividing the patients into two groups, sedation is performed with propofol and remimazolam, respectively, after spinal anesthesia. Compare the patient's body temperature change after surgery.
- Conditions
- Lower Extremity Problem, Gynecologic Disease, Urinary Tract Disease
- Trial name
- NCT05574257
- Testing
- Propofol, Remimazolam
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Bladder Cancer
Comparison of Nerve Stimulating Approach and Interfascial Injection Approach During Sono-guided Obturator Nerve Block
Transurethral resection of bladder tumor (TURB) has been essential treatment for bladder tumours. Direct electrical stimulation of an obturator nerve during the TURB procedures can trigger an inadvertent adductor muscle spasm…
- Trial name
- NCT02452944
- Testing
- nerve stimulator (stimuplex HNS12), ultrasound
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Cesarean Section, Spinal Anesthesia
Pre-Insertion Ultrasound for Lateral-Position Spinal in Cesarean Delivery
The purpose of this study is to evaluate the impact of lumbar ultrasound anatomic mapping using the Accuro device on the number of needle redirections, when performing spinal anesthesia in the lateral decubitus position on…
- Conditions
- Cesarean Section, Spinal Anesthesia, Lumbar Ultrasound
- Trial name
- NCT04592926
- Testing
- Accuro SpineNav3D
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pregnancy, Labor Pain
Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients?
The investigators are interested in determining the utility of ultrasound of the spine for labor epidurals or spinal anesthesia for women in labor or having a cesarean delivery.
- Trial name
- NCT01243216
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Urinary Retention, Uterine Prolapse
Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?
The purpose of the study is to compare the risk of being unable to urinate shortly after surgery, also called acute post-operative urinary retention (POUR) between spinal and general anesthesia in women who undergo outpatient…
- Trial name
- NCT02547155
- Testing
- Spinal anesthesia, General anesthesia
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Post-spinal Shivering
Prophylactic Tramadol Versus Magnesium Sulphate for Prevention of Post-Spinal Shivering
This randomized controlled trial compared prophylactic intravenous tramadol and magnesium sulphate for the prevention of post-spinal shivering among women undergoing elective cesarean section under spinal anesthesia.
- Trial name
- TRAM-MAGS (NCT07838662)
- Testing
- Tramadol, Magnesium Sulphate
- Where
- Pakistan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Punjab Rangers Teaching Hospital Lahore
Vomiting, Nausea
Exteriorized Versus In Situ Uterine Repair at Cesarean Delivery
This study was undertaken to compare the two techniques (exteriorized vs in situ) of uterine repair with respect to patient comfort, hemodynamic changes, surgical time and blood loss, in patients undergoing elective CD under a…
- Conditions
- Vomiting, Nausea, Pain, Hypotension
- Trial name
- NCT00452972
- Testing
- Spinal Anesthesia
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Ossification Posterior Longitudinal Ligament, Cervical Spondylotic Myelopathy
Comparison of IONM Between Remimazolam and Propofol
Inhalation anesthetics significantly can delay latency and reduce amplitude of cortical MEPs and SSEPs signals compared to intravenous anesthetics by acting on not only GABA (γ-aminobutyric acid) receptors but also NMDA…
- Trial name
- NCT04968054
- Testing
- Arm I (Propofol), Arm II (Remimazolam)
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Spinal Anesthesia
Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or Hydromorphone
In the current healthcare system, a short length of stay is paramount, for medical, functional, and financial reasons. Most patients undergoing hip and knee replacement at Hôpital Montfort institution receive spinal anesthetic…
- Trial name
- NCT04280939
- Testing
- spinal anesthesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hopital Montfort
Pain Measurement, Visual Analog Pain Scale
The Analgesic Effect of Intrathecal Hydromorphone Injection on Spinal Anesthesia
The purpose of this study is to evaluate the adequate dose of intrathecal hydromorphone injection for postoperative pain relief after knee arthroscopic surgery.
- Trial name
- NCT01172782
- Testing
- Hydromorphone
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Spinal Anesthesia
Minimum Effective Dose of Ropivacaine for Spinal Anesthesia for Cesarean Delivery
Ropivacaine is one of commonly used anesthetics for spinal anesthesia. Usually L2-3 or L3-4 intervertebral space is chosen for spinal anesthesia.
- Trial name
- NCT02565303
- Testing
- Intervertebral space, Ropivacaine
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai 6th People's Hospital
Temperature Change, Body, Chills
Does Higher OT Temperature and IV Ondansetron Reduce Incidence of PSS in Parturients?
This study will look at the incidence of post-spinal shivering (PSS) among the obstetrics population and will investigate whether higher operation theater (OT) temperature range or/and IV Ondansetron are able to reduce the…
- Conditions
- Temperature Change, Body, Chills, Tremor, Nausea, Postoperative
- Trial name
- HOTON (NCT04654429)
- Testing
- IV Ondansetron 4mg, Higher OT temperature range, Lower OT temperature Range
- Where
- Malaysia
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Dr Lim Siu Min
Postdural Puncture Headache, Regional Anesthesia Morbidity
Postdural Punction Headache After Ceserian Section
The aim of this study is to compare the effect of spinal needle type on postdural puncture headache in patients who will undergo cesarean section.
- Conditions
- Postdural Puncture Headache, Regional Anesthesia Morbidity, Pregnancy Related
- Trial name
- NCT05777694
- Testing
- Patients who underwent cesarean section under spinal anesthesia with 25 gauge spinal needle, Patients who underwent cesarean section under spinal anesthesia with 26 gauge spinal needle, Patients who underwent cesarean section operation under spinal anesthesia with 27 gauge spinal needle
- Where
- Turkey (Türkiye)
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Anesthesia, Pregnancy Related
Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight
This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia.
- Conditions
- Anesthesia, Pregnancy Related, Blockades Neuromuscular
- Trial name
- NCT07685730
- Testing
- ClearSight
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Patients with ASA Physical Status 1 - 2 Who Undergo Surgical Delivery (cesarean Section)
Bupivacaine Effectivity and Efficiency for Regional Spinal Anesthesia in Non-ERACS and ERACS Caesarean Section
The most widely used regional anesthesia technique in Indonesia today is regional anesthesia with the subarachnoid (spinal) blockade method.
- Trial name
- NCT06640816
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitas Jenderal Soedirman
Anesthesia; Reaction, Anesthesia
Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy Procedure
Regional anesthesia is defined as the temporary removal of nerve conduction and pain in certain areas of the body with local anesthetic drugs without causing loss of consciousness.
- Trial name
- NCT05834647
- Testing
- Prilocaine 2%, Hyperbaric Lidocaine 5%
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universitas Sebelas Maret
Cesarean Section Complications, Regional Anesthesia Morbidity
Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index and Shock Indices
Jugular vein collapsibility index and shock indices (Shock index, Modified Shock Index, Diastolic Shock Index) may be useful in estimating post spinal hypotension in cesarean section operations.
- Conditions
- Cesarean Section Complications, Regional Anesthesia Morbidity, Hemodynamic Instability, Shock
- Trial name
- NCT05953129
- Testing
- Right Jugular Vein Collapsibility Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital