Clinical trials: Spinal Anesthesia for Cesarean Section
Analgesia
Comparison of Meperidine and Sufentanil Added to 0.5% Hyperbaric Bupivacaine for Spinal Anesthesia in Cesarean Section
Subarachnoid block is a widely used anesthetic technique for cesarean section. To improve the quality of analgesia and prolong its duration, the addition of intrathecal opioids to local anesthetics has been encouraged.
- Trial name
- NCT04446715
- Testing
- sufentanil, meperidine, Bupivacaine
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Cesarean Delivery, Postoperative Analgesia
Intrathecal Morphine vs Transversalis Fascia Plane Block After Cesarean Delivery
This prospective single-center study compares intrathecal morphine and ultrasound-guided bilateral transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean delivery under spinal…
- Conditions
- Cesarean Delivery, Postoperative Analgesia, Obstetric Anesthesia
- Trial name
- NCT07374133
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Cerebral Oxygen Saturation During Spinal Anesthesia for Cesarean Delivery
Spinal Anesthesia for Cesarean Delivery is Associated With Decreases in Regional Cerebral Oxygen Saturation as Assessed by Near- Infrared Spectroscopy
The cerebral oxygen saturation is assessed by means of near-infrared spectometry in parturients undergoing cesarean delivery under spinal anesthesia.
- Trial name
- NCT01669135
- Testing
- Spinal Anesthesia with cerebral oxygen saturation monitoring
- Where
- Greece
- Volunteers
- 34 people
- Sponsor
- University of Athens
Elective Cesarean Section, Preeclampsia
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
Preeclampsia is a multifocal syndrome reported in 2-8 % of pregnancies. It is diagnosed in the second half of pregnancy by two separate measurements of systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg…
- Trial name
- NCT04370847
- Testing
- Spinal Anesthesia, Intrathecal Bupivacaine, Intrathecal Fentanyl
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Cesarean Delivery, Postoperative Pain
The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery
Working Title The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery Study Description This study aims to evaluate the effects of intrathecal…
- Conditions
- Cesarean Delivery, Postoperative Pain, Cytokine Levels, Chronic Pain, Postoperative
- Trial name
- NCT06684015
- Testing
- İNTRATECHAL MORPHİNE GROUP, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara University
General Anesthesia Versus Spinal Anesthesia on BNP Hormone Levels Preoperatively and Postoperatively in Parturient Cardiac Patient Undergoing C.S
Effect of Different Types of Anesthesia on Perioperative Brain Natriuretic Peptide Levels in Parturient Cardiac Patient Undergoing Elective Cesarean Section
comparing the effect of general anesthesia versus spinal anesthesia on brain natruretic peptide hormone levels preoperatively and postoperatively in parturient cardiac patient undergoing cesarean section
- Trial name
- NCT03460184
- Testing
- G.A Group A:
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Complications; Cesarean Section, Hypotension
Extra Sitting Time After Spinal Anesthesia for Cesarean Section and Fetal Well-being
After injection of the spinal anesthetic drug, women will be allowed to lie down immediately (0-30 sec) or after three minutes (180 sec) of sitting.
- Trial name
- NCT02893696
- Testing
- Various sitting time
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Regional Anesthesia Morbidity, Cesarean Section Complications
Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia
General anesthesia during pregnancy is associated with several major risks including unanticipated difficult airway, pulmonary aspiration, and specific anesthetic effects on the newborn.
- Conditions
- Regional Anesthesia Morbidity, Cesarean Section Complications, Local Anesthetic Complication
- Trial name
- RAMCES (NCT05233462)
- Testing
- standardized dose, adjusted dose
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Caen
Cesarean Section, Pregnancy
Intra-abdominal Pressure, Abdominal Circumference, and Spinal Block Level in Cesarean Section
Spinal anesthesia is commonly used for cesarean section and provides effective anesthesia with rapid onset. However, the spread of spinal anesthesia may vary among pregnant women due to physiological and anatomical changes during…
- Conditions
- Cesarean Section, Pregnancy, Elective Cesarean Section
- Trial name
- NCT07406373
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kutahya Health Sciences University
Pregnancy, Caesarean Section
Pendant Position and Traditional Sitting Position for Successful Spinal Puncture in Spinal Anaesthesia
The aim of this study was to compare the successful spinal puncture among patients with pendant position in comparison with those who used traditional sitting position for caesarean section.
- Trial name
- NCT02753660
- Testing
- Traditional sitting position, Pendant position
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Continuous Fetal Heart Beat Monitor and Analysis After Spinal Anesthesia
Fetal Heart Rate Pattern After Spinal Anesthesia for Scheduled Uncomplicated Cesarean Section
Spinal anesthesia may cause sympathetic blockade which decrease peripheral vascular resistance and bradycardia and then hypotension.
- Trial name
- NCT05776186
- Testing
- Spinal anesthesia with heavy bupivacaine
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Caesarean Section;Stillbirth
Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section
This retrospective study aims to evaluate the fate of children born by cesarean section under spinal anesthesia with or without norepinephrine as vasopressor support for anesthesia.
- Trial name
- NECS (NCT04245891)
- Where
- France
- Volunteers
- 265 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Complications; Cesarean Section, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section
We propose to study the effects on hemodynamics (blood pressure, cardiac output, and central venous pressure) of two doses of bupivacaine for spinal anesthesia during cesarean section: a higher dose of 12 mg to a lower dose of…
- Conditions
- Complications; Cesarean Section, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy, Hemodynamic Instability, Personal Satisfaction
- Trial name
- NCT02036697
- Testing
- Bupivacaine 4.5, Bupivacaine 9, Morphine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Postpartum Hemorrhage, Uterine Atony
Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial
Background: Carbetocin is an established single-dose uterotonic agent for postpartum hemorrhage prophylaxis at elective cesarean delivery.
- Conditions
- Postpartum Hemorrhage, Uterine Atony, Cesarean Section, Blood Loss, Surgical
- Trial name
- CARBOXY-RCT (NCT07636421)
- Testing
- Carbetocin, Oxytocin
- Where
- Saudi Arabia
- Volunteers
- 332 people
- Sponsor
- Mansoura University
Pregnant Women, Pain
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine 2% for Cesarean Section Under Spinal Anesthesia
Over the past 15 years, cesarean delivery is most commonly performed under spinal anesthesia using hyperbaric bupivacaine which provides an adequate sensory and motor block.
- Conditions
- Pregnant Women, Pain, Hypotension
- Trial name
- NCT02973048
- Testing
- Hyperbaric bupivacaine, Hyperbaric prilocaine
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Perioperative Hypothermia, Maternal Hypothermia
Perioperative Forced-Air Warming During Elective Cesarean Delivery Under Spinal Anesthesia
Intraoperative hypothermia is common during cesarean delivery under spinal anesthesia and contributes to maternal discomfort, shivering, and metabolic stress.
- Trial name
- FAM (NCT07757009)
- Testing
- Forced-Air Warming
- Where
- Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Adverse Anesthesia Outcome
The Effect of Preventive Use of Ondansetron in the Cesarean Section Under Spinal Anesthesia
Cesarean section is a frequent procedure in the obstetric surgery. The most widely used anesthesia technique for cesarean delivery is the spinal anesthesia The incidence of spinal anesthesia induced hypotension and bradycardia is…
- Trial name
- NCT02883192
- Testing
- Ondansetron
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Anesthesia; Adverse Effect, Newborn Morbidity
Does the Mode of Anesthesia Affect the Feto-maternal Outcome in Category-1 Caesarean Section
Spinal anesthesia (SA) has become the standard technique in elective cesarean section (CS) as it results in less maternal and neonatal morbidity than general anesthesia (GA) (Grade-A recommendation, NICE).
- Trial name
- NCT04634981
- Testing
- anesthesia of emergency cesarean section
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Benha University
Hypotenstion, Cesarean Resection
Norepinephrine vs. Phenylephrine for Spinal Hypotension in Cesarean Section
This clinical trial was conducted to compare the effectiveness and safety of two medications-norepinephrine and phenylephrine-in treating low blood pressure (hypotension) that often occurs during spinal anesthesia for cesarean…
- Conditions
- Hypotenstion, Cesarean Resection, Anesthesia Spinal, Pregnancy Complications
- Trial name
- Norepinephrine (NCT07153601)
- Testing
- Norepinephrine 4mcg, Phenylephrine 50 mcg
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara