Clinical trials: Spinal Anesthesia for Cesarean Section
Pre-Eclampsia
Restrictive Fluid Therapy in Severe Preeclampsia
Introduction: Pre-eclampsia is a multifactorial syndrome which occurs in hypertension and proteinuria in pregnant women over 20 weeks gestation.
- Trial name
- NCT02214186
- Testing
- Restrictive Fluid Therapy
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Postdural Puncture Headache, Postoperative Nausea and Vomiting
Ondansetron and Dexamethasone for Prevention of PDPH, Nausea, and Vomiting
This prospective, randomized, double-blind, placebo-controlled study was conducted at the Obstetrics and Gynecology Department of El-Minia University Hospital from October 2018 to October 2019.
- Conditions
- Postdural Puncture Headache, Postoperative Nausea and Vomiting, Obstetric Anesthesia Problems
- Trial name
- PDPH-N/V (NCT07068230)
- Testing
- Ondansetron 8mg, Dexamethasone, Saline
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
General Anesthesia Versus Spinal Anesthesia on BNP Hormone Levels Preoperatively and Postoperatively in Parturient Cardiac Patient Undergoing C.S
Effect of Different Types of Anesthesia on Perioperative Brain Natriuretic Peptide Levels in Parturient Cardiac Patient Undergoing Elective Cesarean Section
comparing the effect of general anesthesia versus spinal anesthesia on brain natruretic peptide hormone levels preoperatively and postoperatively in parturient cardiac patient undergoing cesarean section
- Trial name
- NCT03460184
- Testing
- G.A Group A:
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cesarean Section, Hypotension
Prediction of Hypotension During Cesarean Delivery Using Positional Change of Hemodynamic Parameters
This was a prospective observational study between January 2022 and June 2022. The investigators included parturients aged 18 to 45 years, consenting, classified ASA II and III, scheduled for elective or emergency cesarean…
- Conditions
- Cesarean Section, Hypotension, Anesthesia, Spinal, Heart Rate
- Trial name
- NCT05685212
- Where
- Tunisia
- Volunteers
- 121 people
- Sponsor
- Mongi Slim Hospital
Cesarean Section, Pregnancy
Intra-abdominal Pressure, Abdominal Circumference, and Spinal Block Level in Cesarean Section
Spinal anesthesia is commonly used for cesarean section and provides effective anesthesia with rapid onset. However, the spread of spinal anesthesia may vary among pregnant women due to physiological and anatomical changes during…
- Conditions
- Cesarean Section, Pregnancy, Elective Cesarean Section
- Trial name
- NCT07406373
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kutahya Health Sciences University
Pregnancy, Caesarean Section
Pendant Position and Traditional Sitting Position for Successful Spinal Puncture in Spinal Anaesthesia
The aim of this study was to compare the successful spinal puncture among patients with pendant position in comparison with those who used traditional sitting position for caesarean section.
- Trial name
- NCT02753660
- Testing
- Traditional sitting position, Pendant position
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Post Spinal Anesthesia Shivering
Clonidine Versus Granisetron for Shivering Prevension
Prevention of post spinal anesthesia shivering during cesarean section with its associated discomfort, distress, aggravation of pain, increased metabolic demands, and increased oxygen consumption
- Trial name
- NCT06031090
- Testing
- Clonidine Injection, Granisetron Injection, Normal Saline 10 mL Injection
- Where
- Egypt
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Spinal Hypotension
Pilot Study of Real-Time Blood Pressure Decision Support During Cesarean Delivery Under Spinal Anesthesia
This single-center, open-label pilot study evaluates a clinician-facing decision-support algorithm that displays real-time forecasts of maternal mean arterial pressure (MAP), a measure of blood pressure, during elective cesarean…
- Trial name
- NCT07534774
- Testing
- ARX Decision-Support Display
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Hypotension, Anesthesia, Local
The Relationship Between Abdominal Circumference: Hip Ratio and Ephedrine Requirement
This prospective observational study aimed to investigate whether there is a relationship between weight, height, BMI, abdominal circumference (AC), hip circumference (HC), and AC-to-hip ratio with the incidence of hypotension in…
- Conditions
- Hypotension, Anesthesia, Local, Cesarean Section Complications
- Trial name
- NCT05382624
- Testing
- Abdominal circumference was measured at the umbilical level in the standing position at the end of a normal expiration.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Hypotension During Surgery, Hypotension Drug-Induced
Hypotension Prediction Index vs Norepinephrine Infusion for Prevention of Spinal Hypotension for Cesarean Delivery
The goal of this randomized controlled trial is to compare for non inferiority for fetal wellbeing Hypotension Prediction Index - Guided Therapy and Continuous Norepinephrine Infusion in in the Prevention of Spinal…
- Trial name
- NCT05970770
- Testing
- Hypotension Prediction Index, Norepinephrine
- Volunteers
- 150 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obese, Cesarean Section
Conventional Palpation Versus Ultrasound Assisted Spinal Anesthesia in Obstetrics
Spinal anesthesia in obese parturients is commonly difficult yet there are no guidelines to direct best practice. The failure leads to suboptimal patient outcomes.
- Conditions
- Obese, Cesarean Section, Anesthesia Spinal
- Trial name
- NCT05846100
- Testing
- Preprocedural spinal ultrasound, fictional preprocedure spinal ultrasound
- Where
- Tunisia
- Volunteers
- 90 people
- Sponsor
- Mongi Slim Hospital
Cesarean Section, Spinal Anesthesia
Evaluation of Mitochondrial Enzyme Activity in Cesarean Section Patients
The goal of this observational study is to learn about in effects of trace element metabolism, tricarboxylic acid cycle enzyme activities and thiol/disulfide balance in patients who underwent cesarean section under spinal…
- Conditions
- Cesarean Section, Spinal Anesthesia, Thiol Groups
- Trial name
- NCT06206928
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Cesarean Section
Fluid Management for Cesarean Section III
Regional anesthesia, including epidural, spinal and combined epidural spinal anesthesia (CSEA), is a pivotal part in modern anesthesiology.
- Trial name
- FMCS-III (NCT00973414)
- Testing
- Ringer's Lactate, Six percent hydroxyethyl starch
- Where
- China
- Volunteers
- 850 people
- Sponsor
- Nanjing Medical University
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Ondansetron, Cesarean Section
Effects of Ondansetron on Hemodynamics in Cesarean Section Under Spinal Anesthesia
BACKGROUND: Spinal anesthesia (SA) induced maternal hypotension is the most frequent and troublesome complication in cesarean section (CS), compromising both maternal and neonatal well-being.
- Conditions
- Ondansetron, Cesarean Section, Spinal Anesthesia, Hemodynamics
- Trial name
- EffOnd (NCT03629522)
- Testing
- Ondansetron 8Mg/4mL Injection
- Where
- 2 sites in Tunisia
- Volunteers
- 100 people
- Sponsor
- University Hospital, Mahdia
Hypotension Drug-Induced, Cesarean Section Complications
Spinal Anesthesia in Caesarean Section
Spinal anesthesia is a safe technique, widely used and tested in the gynecological field, so as to be considered the first choice technique in cesarean section, which allows to quickly obtain a valid sensor and motor block.
- Conditions
- Hypotension Drug-Induced, Cesarean Section Complications, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Bradycardia
- Trial name
- NCT03743870
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele
Postdural Puncture Headache
Effect of Coffee on Postdural Puncture Headache After Cesarean Section
The purpose of this study is to investigate the effects of postoperative coffee consumption on postdural puncture headache (PDPH) and analgesic use in women undergoing cesarean section with spinal anesthesia.
- Trial name
- NCT07410741
- Testing
- Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Pain
Spinal Anesthesia for Cesarean Delivery: Bupivacaine With or Without Fentanyl
The safest form of anesthesia for Cesarean section is a spinal anesthetic. All spinal anesthetics contain a local anesthetic and/or a narcotic.
- Trial name
- NCT00808327
- Testing
- Bupivacaine, Bupivacaine, fentanyl
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anesthesia, Obestetric
Regional Anesthesia of Cesarean Section
Beta trace protein assay is an indicator of post-spinal CSF leak that predicts the degree of post-spinal headache.
- Trial name
- NCT03556267
- Testing
- spinal needle
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Pregnancy
A Trial of the Use of Ultrasound to Aid the Insertion of Combined Spinal Epidural Anaesthesia
The study will establish whether the use of ultrasound scanning with a purpose built probe will aid the insertion of the needles for epidural and spinal anaesthesia for obese women undergoing elective caesarean section The study…
- Trial name
- NCT00166699
- Testing
- ultrasound
- Where
- 5 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- NHS Greater Glasgow and Clyde