Clinical trials: Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Cyclizine Vs. Dexamethasone for Nausea and Vomiting Following Intrathecal Morphine in Cases of Cesarean Section
Comparing between cyclizine and dexamethasone in preventing PONV after CS under spinal anesthesia with spinal opiate.
- Trial name
- NCT03931135
- Testing
- IV Cyclizine versus IV Dexamethasone for prevention of nausea and vomiting after intrathecal morphine in patients undergoing cesarean section
- Volunteers
- 160 people
- Sponsor
- Assiut University
Left Ventricular Dysfunction, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain
The objective of this study is to assess the effects of intrathecal local anesthetics on left ventricular global longitudinal strain (LVGLS) using transthoracic echocardiography (TTE).
- Conditions
- Left Ventricular Dysfunction, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Global Cardiac Wall Motion Dysfunction
- Trial name
- NCT05650008
- Testing
- Intrathecal local anesthesia
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Hypotension, Pregnancy Related
Non-invasive Haemodynamic Monitoring to Predict Spinal Hypotension During Caesarian Section
Spinal anaesthesia for elective caesarean section is associated with maternal hypotension, secondary to alteration of sympathetic tone and hypovolemia, in up to 70% of cases.
- Conditions
- Hypotension, Pregnancy Related, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
- Trial name
- NCT04608227
- Testing
- Clearsight monitoring
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospital Nord
Complications; Cesarean Section, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Phenylephrine Dose and Mode of Administration for Spinal Anesthesia Induced Hypotension
Three different regimens of phenylephrine are being evaluated to see if one is superior over the other in the maintenance of cardiac output while keeping normotension and/or treating hypotension experienced when receiving spinal…
- Trial name
- NCT02101047
- Testing
- Phenylephrine
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section
The aim of this study is to assess the efficacy of Iv hyoscine butylbromide in preventing Bradycardia during cesarean section under spinal anaesthesia with local anaesthetic and morphine.
- Conditions
- Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Cesarean Section Complications
- Trial name
- NCT04069078
- Testing
- Hyoscine Butylbromide 20 Mg/mL Solution for Injection Ampoule, Normal saline
- Where
- Egypt
- Volunteers
- 173 people
- Sponsor
- Assiut University
Post-Dural Puncture Headache, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Predictive Value of ONSD and NIRS for PDPH
Currently, there is no reliable and effective method available in clinical practice to predict the development of PDPH. Early prediction and prevention of PDPH would reduce the incidence of postoperative complications, thereby…
- Trial name
- NCT07729449
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ordu University
Hypotension, Hypotension on Induction
Perfusion Index as a Predictor of Hypotension Following Sub-arachnoid Block Among Patients Undergoing Lower Segment Caesarean Section
C-section is one of the commonly performed surgical procedures. During this surgical procedure the surgeon cuts into uterine cavity through abdominal wall and takes out the baby.
- Conditions
- Hypotension, Hypotension on Induction, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
- Trial name
- NCT06426784
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Muhammad Haroon Anwar
Hypotension Drug-Induced, Cesarean Section Complications
Spinal Anesthesia in Caesarean Section
Spinal anesthesia is a safe technique, widely used and tested in the gynecological field, so as to be considered the first choice technique in cesarean section, which allows to quickly obtain a valid sensor and motor block.
- Conditions
- Hypotension Drug-Induced, Cesarean Section Complications, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Bradycardia
- Trial name
- NCT03743870
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Hypotension Postprocedural
Ultrasonographic Measurement of Internal Jugular Vein as a Predictor of Hypotension Following Spinal Anesthesia
Hypotension after spinal anesthesia is associated with significant perioperative morbidity and mortality, especially in hypovolemic patients.
- Trial name
- IJV (NCT04486612)
- Testing
- spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Eskisehir Osmangazi University
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Multimodal Approach to the Intrathecal Catheter for Obstetric Accidental Dural Puncture
Accidental dural puncture is an uncommon complication of epidural analgesia and can cause postdural puncture headache.
- Trial name
- NCT05910086
- Testing
- collection of data from the medical record
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Comparing the Effect of Spinal Bupivacaine Versus Spinal Prilocaine on Maternal Blood Pressure in Cesarean Section
one of the most common complications associated with spinal anesthesia is hypotension, which can have adverse effects on both the mother and the fetus.
- Trial name
- NCT06290583
- Testing
- Bupivacaine, Prilocaine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- South Valley University
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
The Ability Of Inferior Vena Caval Distensibility Index With Passive Leg Raising Test To Predict Spinal Anesthesia-induced Hypotension In Elderly Patients Undergoing Infra-umbilical Surgeries. A Prospective Observational Study.
Many previous studies have investigated the ability of various methods such as passive leg raising test , and inferior vena cava collapsibility index in predicting post-spinal hypotension, but none of them have succeeded in…
- Trial name
- NCT05991063
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Effect of Intravenous or Intrathecal Dexmedetomidine on Bupivacaine Spinal Block in Lower Abdominal Surgery
This study is a comparative study will be carried out after approval by the Local Ethical Committee in Al-Azhar University hospital (Assiut) and after obtaining patients' written informed consent.
- Trial name
- NCT06654531
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Hypotension, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Use of Perfusion Index Change as a Predictor of Hypotension During Propofol Sedation in Adult Patients Undergoing Hip Surgery Under Spinal Anesthesia: A Prospective Observational Study
This observational study is to evaluate Perfusion Index Change as a Predictor of Hypotension During Propofol Sedation in Adult Patients Undergoing Hip Surgery Under Spinal Anesthesia.
- Trial name
- NCT03556969
- Testing
- Observation
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Samsung Medical Center
Cesarean Section, Anesthesia, Spinal
Comparison of Standard and Minidose Spinal Anesthesia for Cesarean Section Operation Using Marcaine Spinal 0.5% Heavy
The objectives of this study is to test a combination of low dose local anesthetic Bupivacaine diluted in patient's CSF with lipophilic opiate Fentanyl for optimal spinal anesthesia during Cesarean Section.
- Conditions
- Cesarean Section, Anesthesia, Spinal, Local Anaesthetics Causing Adverse Effects in Therapeutic Use
- Trial name
- NCT01303731
- Testing
- Bupivacaine and Fentanyl, Bupivacaine
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center