Clinical trials: Spinal Cord Injuries, Incomplete
Incomplete Spinal Cord Injury
Non-invasive Brain Stimulation Paired With FES Cycling Post SCI
This project is randomized controlled trial which will explore the effect of pairing repetitive Transcranial Magnetic Stimulation (rTMS) with Functional Electrical Stimulation (FES) Cycling on lower extremity function in people…
- Trial name
- NCT05975606
- Testing
- repetitive transcranial magnetic stimulation (rTMS), functional electrical stimulation (FES) cycling
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Western University, Canada
INCOMPLETE SPINAL CORD INJURY (ASIA D), Able Bodied
Examining the Effect of Acute Intermittent Hypoxia on Serum Blood Proteins and Lower Limb Function
The goal of this study is to clarify mechanisms of acute intermittent hypoxia and to examine the effect on lower limb function in persons with chronic, incomplete spinal cord injury.
- Trial name
- NCT06906536
- Testing
- Acute Intermittent Hypoxia (AIH)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
SCI - Spinal Cord Injury, Incomplete Spinal Cord Injury
Stimulation to Enhance Walking Post-SCI
This pilot study will investigate the effects of transcutaneous direct current stimulation (tsDCS) on walking function in individuals with incomplete spinal cord injury.
- Trial name
- NCT03702842
- Testing
- Soterix Medical tsDCS stimulator, Locomotor training
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Complete or Incomplete Paraplegia/quadriplegia, Spinal Cord Injury
Research on Wireless Brain Implant System for General Control of External Devices
The clinical trial aims to evaluate the safety and efficacy of the minimally invasive, wireless brain-machine interface system (WRS) in enabling general brain control of external devices, such as a cursor and other assistive…
- Conditions
- Complete or Incomplete Paraplegia/quadriplegia, Spinal Cord Injury, Brainstem Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- RISE (NCT06829212)
- Testing
- WRS
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Shanghai StairMed Technology Co., Ltd.
Neurogenic Bladder, Spinal Cord Injuries (Complete and Incomplete)
Spinal COrd NeuromodulaTor by SpIneX and ScoNE to Treat NeurogeniC BladdEr - SCONE "CONTINENCE" Clinical Study
The purpose of this study is to evaluate the effectiveness and safety of SCONE neuromodulation therapy after 12 weeks of therapy in comparison to inactive sham control in improving symptoms of Neurogenic Lower Urinary Tract…
- Conditions
- Neurogenic Bladder, Spinal Cord Injuries (Complete and Incomplete), Stroke, Multiple Sclerosis
- Trial name
- CONTINENCE (NCT05301335)
- Testing
- SCONE
- Where
- 12 sites in United States, Canada and 1 more
- Volunteers
- 126 people
- Sponsor
- SpineX Inc.
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Neuromodulation With Spinal Stimulation Methods
This is a pilot research study to test the protocols needed for transcutaneous spinal electrical stimulation in persons living with spinal cord injury (SCI). Up to 24 participants will be enrolled.
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Paraplegia, Spinal, Paraplegia, Incomplete
- Trial name
- NCT06272279
- Testing
- spinal stimulation-DCS, spinal stimulation-EPS
- Where
- 2 sites in Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Spinal Cord Injury, Incomplete Spinal Cord Injury
Tele-rehabilitation Using TDCS Combined with Exercise in People with Spinal Cord Injury
This study aims to explore the effect of trans cranial direct current stimulation (tDCS) combined with self-exercise at home for 1 month training (3 sessions/week, for 4 weeks).
- Trial name
- NCT06079138
- Testing
- Transcranial direct current stimulation (Active), Telerehabilitation exercise
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Incomplete Spinal Cord Injury
Restoration of Arm Function in People With High-level Tetraplegia
Functional electrical stimulation (FES) has been used to activate paralysed muscles and restore movement after spinal cord injury and stroke.
- Trial name
- NCT04102826
- Testing
- Functional electrical stimulation (FES)
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Incomplete Spinal Cord Injury
The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients
The purpose of this study is to further establish safety and efficacy of the BQ EMF treatment of chronic SCI subjects who demonstrate stability in The Graded and Redefined Assessment of Strength, Sensibility and Prehension…
- Trial name
- NCT04050696
- Testing
- BQ 1.2
- Where
- 3 sites in United States, Israel
- Volunteers
- 8 people
- Sponsor
- BrainQ Technologies Ltd.
Incomplete Spinal Cord Injury
Powered Exoskeleton Combined With Functional Electrical Stimulation in Clinical Practice
After partial spinal cord injury, gait deficits may be present and often remain even after intensive rehabilitation. New robotic technologies have recently emerged to help augment the extent of rehabilitation.
- Trial name
- NCT04568928
- Testing
- OLTP/PE + FES
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Laval University
Incomplete Spinal Cord Injury
Effects of tDCS With Gait Training on Leg Performance in Incomplete Spinal Cord Injury
This study aim to investigate the effects of anodal transcranial direct current stimulation combined with gait training for 5 consecutive session on gait performance, balance, sit to stand performance and quality of life in…
- Trial name
- NCT04910412
- Testing
- transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Complete Spinal Cord Injury, Incomplete Spinal Cord Injury
Algorithmic-Based Evaluation and Treatment Approach for Robotic Gait Training
The purpose of this study is to develop an algorithmic-based evaluation and treatment approach for wearable robotic exoskeleton (WRE) gait training for patients with neurological conditions.
- Conditions
- Complete Spinal Cord Injury, Incomplete Spinal Cord Injury, Acquired Brain Injury, Multiple Sclerosis
- Trial name
- NCT03057652
- Testing
- ReWalk, EKSO, REX
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Incomplete Spinal Cord Injury
Neurofeedback to Improve Spasticity After Incomplete Spinal Cord Injury
After incomplete spinal cord injury (iSCI), many people still have control over their upper and/or lower limbs, but secondary conditions such as spasticity impair the function they have left.
- Trial name
- NCT04849676
- Testing
- visual neurofeedback
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- NHS Greater Glasgow and Clyde
Incomplete Spinal Cord Injury, Transverse Myelitis
Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance
Robotic therapies aim to improve limb function in individuals with neurological injury. Modulation of robotic assistance in many of these therapies is achieved by measuring the extant volitional strength of limb muscles.
- Trial name
- NCT05249595
- Testing
- Surface electromypgraphy-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Surface electromypgraphy and ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Spinal Cord Injuries, Incomplete Spinal Cord Injury
A Novel System for Quasi Real-Time Tracking of Neuromuscular Responses During NMES
Neuromuscular electrical stimulation (NMES) remains as one of the effective rehabilitation modalities for addressing recovery of neuromuscular function after a spinal cord injury (SCI).
- Trial name
- NCT05243576
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Spinal Cord Injuries, Tetraplegia, Unspecified, Incomplete, Chronic
Improving Hand Recovery With Neuromodulation in Tetraplegia
This study will examine a form of non-invasive brain stimulation applied with intensive therapy of the arm and hand. The goal of the study is to determine if arm and hand function can be improved in people with incomplete…
- Trial name
- IGNITE (NCT03954496)
- Testing
- transcranial direct current stimulation, Intensive upper extremity motor training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Sara Shahid Salles
Spinal Cord Injury, Incomplete Spinal Cord Injury
Evaluation of Robotic Exoskeletons Therapy for Gait Rehabilitation in Patients With Incomplete Spinal Cord Injury.
The objective of the study is to assess the efficacy of the Exo-H2 robotic exoskeleton for walking rehabilitation of people with incomplete spinal cord injury.
- Trial name
- NCT03477123
- Testing
- Walking therapy with Exo-H2 exoskeleton
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Nacional de Parapléjicos de Toledo
Spinal Cord Injuries, Paraplegia, Spinal
Modeling, Optimization, and Control Methods for a Personalized Hybrid Walking Exoskeleton
The central objective of this study is to validate new algorithms that coordinate between functional electrical stimulation (FES) and the exoskeleton during sitting-to-standing, walking, and standing-to-sitting movements.
- Conditions
- Spinal Cord Injuries, Paraplegia, Spinal, Paraplegia, Incomplete
- Trial name
- NCT04453943
- Testing
- Exoskeleton Walking - with or without FES, Exoskeleton Sitting to Standing - with or without FES
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Stroke, Traumatic Brain Injury
Study Examines the Feasibility, Safety and Benefits of Using a Specific Suspension Walking Device for Patients With Neurological Damage
This monocentric descriptive study addresses feasibility, safety and benefits of using a specific suspension walking device for patients with severe neurological injuries in the neuroICU of Montpellier University Hospital…
- Conditions
- Stroke, Traumatic Brain Injury, Incomplete Cervical Spinal Cord Injury, Other Brain Injuries
- Trial name
- Walk-Up (NCT04300491)
- Testing
- Suspension walking training
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Incomplete Spinal Cord Injury
Effects of Transcutaneous Spinal Direct Current Stimulation in Incomplete Spinal Cord Injury
The purpose of the study is to investigate the effects of a novel therapeutic approach with transcutaneous spinal direct current stimulation (tsDCS) to promote functional recovery and spasticity in chronic spinal cord injury…
- Trial name
- NCT03249454
- Testing
- Anodal tsDCS, Cathodal tsDCS
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston