Clinical trials: Spinal Cord Injury(SCI)
Cervical Spinal Cord Injury
Supporting Patient Decisions About UE Surgery in Cervical SCI
The goal of this study is to collect and describe patient and caregiver reported outcomes regarding surgical and non-surgical treatment for improving hand and arm function in the setting of cervical spinal cord injury.
- Trial name
- NCT03464409
- Testing
- Semi-structured interview, Spinal Cord Independence Measure (SCIM-SR), SF-36
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- Washington University School of Medicine
Spinal Cord Injury
Safety Study of Outdoor and Indoor Mobility in People With Spinal Cord Injury (ROBOtics Spinal Cord Injury EKSO).
The aim of this study will be to evaluate the safety and the efficacy of a new robotic exoskeleton device in subjects with Spinal Cord Injury (SCI) and in subjects with other neurological disease with an impairment of lower limbs.
- Trial name
- ROBOSCIEKSO (NCT02065830)
- Testing
- EKSO
- Where
- 2 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Chronic Spinal Cord Injury
LIFT Home Study of Non-Invasive ARC Therapy for Spinal Cord Injury
The LIFT Home Study is an observational, single-arm study designed to assess the safety of non-invasive electrical spinal stimulation (ARC Therapy) administered by the LIFT System to treat upper extremity functional deficits in…
- Trial name
- NCT05284201
- Testing
- LIFT System
- Where
- 5 sites in United States
- Volunteers
- 17 people
- Sponsor
- ONWARD Medical, Inc.
SCI - Spinal Cord Injury, Motor Imagery
Near-Infrared Imaging of Motor Imagery Effects in Spinal Cord Injury
The primary objective of this clinical trial is to investigate the efficacy of motor imagery-based brain-computer interface (MI-BCI) technology in improving motor function among patients with spinal cord injury (SCI), as well as…
- Conditions
- SCI - Spinal Cord Injury, Motor Imagery, Brain-Computer Interfaces
- Trial name
- NCT07106060
- Testing
- EEG-based rehabilitation training device (L-B300), EEG-based rehabilitation training device (L-B300)（Not connected）
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shengjing Hospital
Spinal Cord Injuries
Scale Up of Project Workout on Wheels Internet Intervention (WOWii)
This study is designed is to test the feasibility, fidelity, and effectiveness of scaling up an evidence- and theory-based virtually delivered physical activity intervention (WOWii) for individuals living with chronic SCI for…
- Trial name
- WOWii (NCT05353842)
- Testing
- WOWii Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Craig Hospital
Overweight, Obese
Obesity/Overweight in Persons With Early and Chronic Spinal Cord Injury (SCI)
The purpose of this study is to determine how exercise and nutritional guidance and supplementation affects your physical fitness, risk for heart disease, your body's ability to burn fat, and your opinions about your health.
- Conditions
- Overweight, Obese, Spinal Cord Injury
- Trial name
- NCT01467817
- Testing
- Lifestyle Intervention, Exercise Control
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Miami
Spinal Cord Injury, Orthostatic Hypotension
Prevention of Orthostatic Hypotension With Electric Stimulation in Persons With Acute SCI
Background: The presence of orthostatic hypotension (OH) as a consequence of blood volume redistribution during verticalisation in persons with spinal cord injury (SCI) is a common condition.
- Trial name
- NCT01891110
- Testing
- ES of the abdominal muscles, ES of the limb muscles, ES of limbs & abdomen
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Spinal Cord Injuries
Combined Magnetic Stimulation and Ultrasound for Detrusor Overactivity in SCI
This clinical trial aims to investigate whether the combination of high-frequency sacral nerve root magnetic stimulation and bladder-directed ultrasound therapy can effectively improve detrusor overactivity (involuntary bladder…
- Trial name
- NCT07704268
- Testing
- Transcranial Magnetic Stimulation (TMS) Device /Ultrasound therapy device
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Shengjing Hospital
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Brain Plus Spinal Stimulation for Cervical SCI
The goal of this project is to strengthen residual corticospinal tract (CST) connections after partial injury using combined motor cortex and spinal cord stimulation to improve arm and hand function after spinal cord injury…
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Tetraplegia/Tetraparesis
- Trial name
- NCT04727866
- Testing
- transcutaneous spinal direct current stimulation (tsDCS) - coronal, transcutaneous spinal direct current stimulation (tsDCS) - caudal, transcutaneous spinal direct current stimulation (tsDCS) - rostral
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Cervical Spinal Cord Injruy
Improving SCI Rehabilitation Interventions by Retraining the Brain
The Long-term goal of this project is to develop upper limb rehabilitation interventions that can be utilized for cervical Spinal Cord Injury survivors.
- Trial name
- NCT03892746
- Testing
- Active tDCS + task oriented practice
- Where
- 4 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Spinal Cord Injuries
Improving Gait in Patients With Spinal Cord Injuries
This study is part of a larger clinical trial that examines the potential of a 12-week treadmill-training program to improve walking in patients with spinal cord injuries (SCIs).
- Trial name
- NCT00060983
- Testing
- Body weight supported locomotor training, Functional electrical stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Spinal Cord Injuries
Spinal Cord Stimulation for Autonomic Recovery in Inpatient Rehabilitation After Acute SCI
This study is a randomized, single-blind, two-arm sham-controlled clinical trial to evaluate the safety and efficacy of transcutaneous spinal cord stimulation (tSCS) over the lower thoracic and upper lumbar spinal cord segments…
- Trial name
- NCT06540859
- Testing
- Transcutaneous Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Washington
Incomplete Spinal Cord Injury
Effects of Transcutaneous Spinal Direct Current Stimulation in Incomplete Spinal Cord Injury
The purpose of the study is to investigate the effects of a novel therapeutic approach with transcutaneous spinal direct current stimulation (tsDCS) to promote functional recovery and spasticity in chronic spinal cord injury…
- Trial name
- NCT03249454
- Testing
- Anodal tsDCS, Cathodal tsDCS
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injuries, Paraplegia
ExoAtlet II For SCI Patients
This study will evaluate the ExoAtlet II exoskeleton for safety and effectiveness of providing persons with a spinal cord injury (SCI) who are non-ambulatory or have limited ambulatory function, to stand up and ambulate under a…
- Trial name
- EXOATLET2SCI (NCT04215081)
- Testing
- Gait training using ExoAtlet exoskeleton
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- COSMO ROBOTICS CO., Ltd
Neuropathic Pain, SCI - Spinal Cord Injury
Transcutaneous Intercostal Nerve Stimulation in Spinal Cord Injury
The purpose of this study is to determine the safety, feasibility, and effectiveness of electric stimulation of the nerves along the intercostal nerves on pain and spasticity in spinal cord injury patients.
- Trial name
- TINS (NCT04506099)
- Testing
- TINS Active protocol
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injury
Integrated Tele-exercise for Individuals With Spinal Cord Injury
The objective of this study is to examine the efficacy of an integrated, participant-centered tele-health physical activity program for individuals with SCI on psychological and social factors through a parallel mixed-methods…
- Trial name
- NCT05360719
- Testing
- Group tele-exercise
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Drexel University
Spinal Cord Injuries, Cognitive Dysfunction
Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study
This study seeks to conduct a pilot study to test whether a cognitive training program can improve processing speed abilities in individuals with acute traumatic spinal cord injury.
- Conditions
- Spinal Cord Injuries, Cognitive Dysfunction, Cognitive Impairment, Acute Spinal Cord Injury
- Trial name
- SCI-IQ (NCT06452264)
- Testing
- game-like computerized activities
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kessler Foundation
Cervical Spinal Cord Injury
Diaphragm Pacing in Individuals With Spinal Cord Injuries
This project will evaluate the effects of intramuscular diaphragm stimulation (pacing) and test the hypothesis that diaphragm pacing enhances neuromuscular diaphragm activation and respiratory function in adults with cervical…
- Trial name
- NCT04179799
- Testing
- Diaphragm Pacing
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Spinal Cord Injuries, Orthostatic Hypotension
Speed of Robotic Leg Movements and Orthostatic Hypotension in Subacute SCI
This study seeks to evaluate whether the speed (cadence) of lower extremity robotic movement has an impact on orthostatic hypotension and upright tolerance when training with the ErigoPro robotic tilt-stepper.
- Trial name
- NCT04029974
- Testing
- ErigoPro
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Methodist Rehabilitation Center
Spinal Cord Injuries and Disorders (SCI/D)
Caring Connections: A Program to Alleviate Social Isolation and Loneliness in Individuals Living With Spinal Cord Injury
This study will use a randomized controlled design with an active attention control group to evaluate an intervention intended to reduce social isolation and loneliness in persons with SCI/D.
- Trial name
- NCT05295108
- Testing
- Caring Connections, Attention control
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Chicago Association for Research and Education in Science