Clinical trials: Spinal Curvatures
Scoliosis Idiopathic
Rapid Postoperative Recovery Pathway in Adolescent Idiopathic Scoliosis.
the study will evaluate the clinical outcomes of an intra- and postoperative fast-track protocol in patients undergoing instrumented posterior arthrodesis surgery for adolescent idiopathic scoliosis.
- Trial name
- NCT05011734
- Testing
- Fast Track recovery pathway
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Istituto Ortopedico Rizzoli
Scoliosis, Kyphosis
Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study
This will be an open label, prospective study to determine the association between specific genotypes, epigenetics and behavioral factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic and side…
- Conditions
- Scoliosis, Kyphosis, Kyphoscoliosis, Pectus Excavatum
- Trial name
- NCT02998138
- Where
- 5 sites in United States
- Volunteers
- 880 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Adolescent Idiopathic Scoliosis (AIS)
Relationship Between Spinopelvic Parameters and Plantar Pressure in Adolescents With Lenke Type I and V Scoliosis
Adolescent idiopathic scoliosis (AIS) affects the alignment of the spine and body posture, which can influence balance and the way body weight is distributed through the feet.
- Trial name
- AIS-PLANTAR (NCT07810140)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Aslıhan içer
Spinal Muscular Atrophy Type I, Scoliosis
The Effect of Spinal Orthosis on the Development of Scoliosis and Chest Deformity in Type I Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is a serious neuromuscular disease characterized by the degeneration of alpha motor neurons in the spinal cord, resulting in progressive proximal muscle atrophy and denervation.
- Conditions
- Spinal Muscular Atrophy Type I, Scoliosis, Chest Deformities, Spinal Orthosis
- Trial name
- NCT05878418
- Testing
- Thoracolumbosacral Spinal Orthosis (TLSO), Trunk Exercise (TE), Pulmonary Rehabilitation(PR) and Pulmonary Care (PC)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medipol University
Scoliosis, Spinal Curvatures
Preventing Curve Progression and the Need for Bracing in Adolescent Idiopathic Scoliosis With Calcium + Vitamin D Supplementation
There is an association between adolescent idiopathic scoliosis (AIS) and low bone mass which has been reported to be a significant prognostic factor for curve progression.
- Conditions
- Scoliosis, Spinal Curvatures, Spinal Diseases, Bone Health
- Trial name
- NCT03533010
- Testing
- Ca500mg, VitD800IU
- Where
- Hong Kong
- Volunteers
- 199 people
- Sponsor
- Chinese University of Hong Kong
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Scoliosis, Restrictive Pulmonary Disease
Cardiorespiratory Assessment Prior to Scoliosis Surgery: a 10-year Experience at a Specialized Scoliosis Center
this study involves adult patients who underwent scoliosis surgery within the last 10 years. The aim of this study is to assess the frequency of scoliosis-related respiratory complications in patients requiring orthopedic…
- Conditions
- Scoliosis, Restrictive Pulmonary Disease, Pulmonary Hypertension, Restrictive Breathing Pattern
- Trial name
- RespiSco (NCT07760441)
- Testing
- respiratory function test
- Where
- France
- Volunteers
- 174 people
- Sponsor
- Poitiers University Hospital
Juvenile; Scoliosis, Scoliosis Idiopathic
Studying Melatonin and Recovery in Teens
The goal of this feasibility clinical trial is to learn if melatonin can help teens having major musculoskeletal surgery by promoting healthy sleep.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgerySMART (NCT06093477)
- Testing
- Fast-Dissolve Melatonin Pill
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Scoliosis
Study of 3D Scanning for Adolescent Scoliosis
The investigators aim to validate three-dimensional topographical scanning technology as a tool for evaluation of scoliosis. Through the incorporation of 3D topographical technology in the measurement of deformity, the…
- Trial name
- NCT06035952
- Testing
- 3D topographical scan
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NSite Medical
Exercise, Low Back Pain
McGill Exercise With and Without 3-dimensional Myofascial Release Technique in Non-specific Low Back Pain
Low back pain is a complex of musculoskeletal disorders or muscular imbalance and one of the most common problems of patients referred to physiotherapy clinics, but still diagnosis and especially the provision of special back…
- Conditions
- Exercise, Low Back Pain, Lumbar, Lordosis
- Trial name
- NCT07441031
- Testing
- McGill exercise with 3 D Myofascial Release., McGill exercise without 3-D MFR
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Scoliosis
The Effect of Magnesium Sulfate on Motor and Somatosensory Evoked Potentials in Children Undergoing Scoliosis Surgery
The primary objective of this study is to determine whether magnesium sulfate has a clinically important effect on the amplitude and latency of somatosensory and motor evoked potentials in patients undergoing surgical correction…
- Trial name
- NCT01148888
- Testing
- Magnesium
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- The Hospital for Sick Children
Hyperkyphosis, Walking, Difficulty
Walking and Balance Related to Sagittal Spinal Posture Alignment
This study aims to improve understanding of the relationship between spinal alignment and walking and balance in people who have degenerative spinal conditions.
- Conditions
- Hyperkyphosis, Walking, Difficulty, Balance; Distorted, Spinal Disease
- Trial name
- WiSPA (NCT04008459)
- Testing
- Therapeutic exercise class
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- University of Oxford
Hamstring Tightness, Lumbar Lordosis
Hamstring Tightness and Lumbar Lordosis Angel Across Functional Sitting Posture.
The goal of this observational study is to learn about the relationship between hamstring tightness and the lumbar lordosis angle in sedentary adults across different sitting postures.
- Conditions
- Hamstring Tightness, Lumbar Lordosis, Sedentary Behavior, Posture Sitting Position
- Trial name
- LLA-HT (NCT07682142)
- Testing
- Hamstring tightness and lumbar lordosis assessment
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
Displacement of Intervertebral Disc Without Myelopathy
Results of Mini-open Discectomy According to Sagittal Profile
In the normal healthy population, the sagittal alignment can be divided into four types based on the size of the sacral slope and lumbar lordosis.
- Trial name
- NCT05927662
- Testing
- lumbar discectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Kyphosis
DNS vs Thoracic Stabilization Exercises in Thoracic Kyphosis
This randomized controlled trial aims to compare the effects of Dynamic Neuromuscular Stabilization (DNS) exercises and thoracic stabilization exercises on thoracic erector spinae muscle strength, thoracic kyphosis angle, pain…
- Trial name
- TK-DNS-TS (NCT07255794)
- Testing
- Dynamic Neuromuscular Stabilization Exercises, Thoracic Stabilization Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Esra BECENI
Scoliosis, Back Pain
InterFuse® S and T for the Treatment of Scoliosis, Spondylolisthesis and Degenerative Disc Disease (DDD)
The primary objective of this prospective, post-market study is to collect data to assess the long term outcome of a broad contact modular interbody device in the form of the InterFuse S™ or InterFuse T™ device in patients…
- Trial name
- NCT02659722
- Testing
- InterFuse
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Vertebral Technologies, Inc.
Spinal Muscular Atrophy, Spine Deformity
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
The primary objective of the clinical investigation is to demonstrate successful clinical use of the ThecaFlex DRx™ System in delivering nusinersen in subjects with spinal muscular atrophy (SMA).
- Conditions
- Spinal Muscular Atrophy, Spine Deformity, Scoliosis
- Trial name
- PIERRE (NCT05866419)
- Testing
- ThecaFlex DRx System
- Where
- 21 sites in United States, Germany and 3 more
- Volunteers
- 90 people
- Sponsor
- Alcyone Therapeutics, Inc
Genu Varum, Genu Valgus
IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms
While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether…
- Conditions
- Genu Varum, Genu Valgus, Flat Feet, Cavus Foot
- Trial name
- MOTOR-CHILD (NCT05763901)
- Testing
- Clinical tests and motor control evaluation using Inertial Measurement Units
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Istituto Ortopedico Rizzoli
Scoliosis
Anesthesiologic Management Effect on Perioperative Outcome in Scoliosis Surgery
Alteration of evoked potentials is described in cases with using inhalation anaesthetics. Muscle relaxants are contraindicated in case of motor evoked potentials except for initial dose for intubation of the patient.
- Trial name
- SCOL (NCT04423146)
- Testing
- The evocation of reproducible motor evoked potential according to the different BIS levels
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Brno University Hospital
Scoliosis Idiopathic, Exercise
Effectiveness of Scientific Exercise Approach to Scoliosis in Mild Idiopathic Scoliosis
İdiopathic scoliosis is a three dimensional deformity with lateral deviation and rotation of the spine. In idiopathic scoliosis, scoliosis-specific exercises are utilized as a primary treatment for moderate curves and as a…
- Conditions
- Scoliosis Idiopathic, Exercise, Quality of Life, Treatment
- Trial name
- NCT06039657
- Testing
- SEAS training, Standard Care
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hacettepe University