Clinical trials: Spinal Decompression
Lumbar Spinal Stenosis
Predictors of Decompressive Laminectomy Outcomes
Decompressive laminectomy (DL) is the most common type of back surgery performed in older adults; DL treats lumbar spinal stenosis (LSS), a degenerative narrowing of the spinal canal causes pain and trouble walking.
- Trial name
- NCT02215551
- Where
- 7 sites in United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Failed Back Surgery Syndrome
Low Level Laser Therapy to Reduce Comorbidity in Spinal Surgery
Each year, more than one million individuals worldwide are submitted to laminectomies, with a failure rate higher than 40%. Postlaminectomy epidural adhesion is implicated as a main cause of ''failed back surgery syndrome'' and…
- Trial name
- LASPINE (NCT02529657)
- Testing
- Low Level Laser Therapy
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Lumbar Disc Herniation
Comparison of Different Treatment Methods in Lumbal Disc Herniation Treatment
The aim of this study is to determine the effectiveness of three different treatment methods which consists spinal decompression, deep friction massage and exercise.
- Trial name
- NCT02572622
- Testing
- non -surgical spinal decompression therapy, deep friction massage,, electrotherapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hemifacial Spasm
Hemifacial Spasm and Desflurane
Patients are chosen to participate in this study because they will undergo a particular type of brain surgery to treat their hemifacial spasm.
- Trial name
- HFS (NCT01726725)
- Testing
- desflurane
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Lumbar Spinal Stenosis
Vertos Mild - Post Market Patient Outcomes
This is a single-center study evaluating the outcomes of patients with painful lumbar spinal stenosis who were treated with the mild procedure (minimally invasive lumbar decompression.
- Trial name
- NCT01076244
- Testing
- Minimally Invasive Lumbar Decompression
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Center for Pain Relief, Inc.
Post-laminectomy Syndrome, Axial Back Pain
Evaluation of Objective Outcomes With the Use of an Activity Tracker During the Trial Period of Spinal Cord Stimulation
For this study the investigators will conduct five-day trial periods for spinal cord stimulator (SCS) effectiveness-once a patient is deemed to be a possible SCS candidate, the trial leads are implanted and they are asked to…
- Trial name
- NCT02641223
- Testing
- spinal cord stimulator
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Postoperative Pain
Use of IV Acetaminophen in the Treatment of Post Operative Pain in Patients Undergoing Craniotomy and Spine Surgery
The purpose of this study is to investigate the effectiveness of intravenous acetaminophen (Tylenol) for post operative pain control in patients undergoing craniotomies (brain surgery) and spine surgery.
- Trial name
- NCT03261310
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Postoperative Pain
Fentanyl 12 Mcg Transdermal Patch For Postoperative Pain
The investigators designed a prospective randomized study to investigate the effect of fentanyl 12 mcg transdermal patch on postoperative pain following unilateral, single-level laminectomy/discectomy.
- Trial name
- NCT03199157
- Testing
- Fentanyl transdermal patch
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Baskent University
Lumbar Disc Herniation, Lumbar Disc Disease
GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries
The purpose of this study is to determine the optimal anesthetic routine for lumbar decompression surgery. General Anesthesia is the standard of care in spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
- Trial name
- NCT05444751
- Testing
- General anesthetic, SA + ESP
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Surgical Site Infection, Antibiotics Prophylaxis
Cefuroxime vs Ceftriaxone for SSI Prevention in Neurosurgery
BACKGROUND: Surgical site infection (SSI) is potentially catastrophic in neurosurgical procedures, causing poor in-hospital outcomes in more than half of those affected and significantly increased length of hospital stay.
- Trial name
- NCT05398081
- Testing
- Cefuroxime (Zinnat®), Ceftriaxone (Rocephin®)
- Where
- Nigeria
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Dr. Promise Tamunoipiriala Jaja
Lumbosacral Spinal Stenosis
Irrigation Endoscopic Decompressive Laminotomy
The classic laminectomy for surgical treatment of spinal stenosis has considerable morbidity .This is further magnified by the disease being more common in elderly with associated medical comorbidities and being usually global…
- Trial name
- NCT01991912
- Testing
- open lumbar decompression
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cubital Tunnel Syndrome
Electrical Nerve Stimulation of the Ulnar Nerve
Cubital tunnel syndrome is caused by compression of the ulnar nerve at the elbow. This leads to symptoms such as chronic hand weakness, numbness and pain.
- Trial name
- ESTIM (NCT02566616)
- Testing
- Ulnar Nerve Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago