Clinical trials: Spinal Decompression
Spinal Stenosis
Surgical Versus Nonsurgical Treatment for Spinal Stenosis
Lumbar spinal stenosis (a narrowing of spaces in the backbone that results in pressure on the spinal cord and/or nerve roots) is a condition that occurs frequently, particularly in the elderly.
- Trial name
- NCT00022776
- Testing
- Surgical decompression, Physical therapy
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of Pittsburgh
Spinal Fractures
Short Segment Fixation in Thoracolumbar Osteoporotic Fracture
Although long-segment posterior spinal fixation might provide more rigid fixation, the procedure increases perioperative morbidities in the elderly.
- Trial name
- NCT02719340
- Testing
- short segment fixation
- Volunteers
- 20 people
- Sponsor
- National Cheng-Kung University Hospital
Nerve Entrapments, Pelvic Pain
Integration of Intraoperative Neuromonitoring Into Decompression Surgery
To describe a novel technique by integrating the intraoperative neurophysiological monitoring (IONM) into laparoscopy to protect pelvic nerves by continuously monitoring when they are at risk during surgery.
- Trial name
- NCT06009640
- Testing
- Intraoperative neurophysiological monitoring with Nicolet Endeavor IOM Machine
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Lumbar Disc Herniation
Remission of Lumbar Disc Herniation by Physiotherapy
This study was conducted with the aim of determining whether or not Non surgical spinal decompression therapy was effective in remission of herniation, decreasing pain and improving functional status.
- Trial name
- NCT02699164
- Testing
- DRX 9000, Axiom Worldwide, Tampa, Florida, physiotherapy, spinal stabilization exercise
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Adjacent Segment Degeneration
PEEK Versus Silicon Interspinous Spacer for Reduction of Supradjacent Segment Degeneration
A retrospective study that aims to report Adjacent Segment Degeneration (ASD) incidence and spinopelvic balance in short lumbosacral instrumentation for degenerative lumbar spinal stenosis.
- Trial name
- WallisvsDiam (NCT03477955)
- Testing
- PEEK interspinous spacer
- Volunteers
- 55 people
- Sponsor
- University Hospital of Patras
Low Back Pain, Lumbar Disc Disease
Efficacy of Mechanical Traction and Spinal Decompression Treatments in Patients With Low Back Pain
Motorized traction and non-surgical spinal decompression treatments are relatively new treatments for which there is insufficient evidence in the literature.
- Conditions
- Low Back Pain, Lumbar Disc Disease, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT05617924
- Testing
- Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Afyonkarahisar Health Sciences University
Diabetic Ulcer of Plantar Aspect of Left Foot, Diabetic Ulcer of Plantar Aspect of Right Foot
Nerve Decompression for Ulcer Recurrence Avoidance (DURA)
Anecdotal reports and scientific literature suggest that the risk of recurrence of diabetic foot ulcers can be minimized by nerve decompression procedures at anatomic sites of nerve pinching and entrapment.
- Conditions
- Diabetic Ulcer of Plantar Aspect of Left Foot, Diabetic Ulcer of Plantar Aspect of Right Foot, Diabetic Polyneuropathy
- Trial name
- DURA (NCT01762085)
- Testing
- nerve decompression
- Where
- 6 sites in United States
- Volunteers
- 120 people
- Sponsor
- Association of Extremity Nerve Surgeons
Anterior Spinal Artery Compression Syndromes, Cervical Region
Effect of Placing the Endotracheal Tube Beyond Cervical C7 Level in Anterior Cervical Decompression and Fusion Surgery
Endotracheal intubation is performed to secure the patient's airway during general anaesthesia undergoing surgery. The procedure involves placing a tube known as endotracheal tube (ETT) mouth into the trachea.
- Trial name
- NCT06473077
- Testing
- ETT beyond C7 level
- Where
- Malaysia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Lumbar Spondylolisthesis
Clinical Study of Bilateral Decompression With Interbody Fusion for Spondylolisthesis
Laminectomy with PLIF has been shown to achieve satisfactory clinical outcomes, but it leads to potential adverse consequences associated with extensive disruption of posterior bony and soft-tissue structures.
- Trial name
- NCT02972190
- Testing
- Bilateral decompression with TLIF, laminectomy with PLIF, Pedicle screw and interbody cage
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Lumbar Spinal Canal Stenosis
Irrigation Endoscopic Decompression
To evaluate a new endoscopic technique for lumbar spinal canal decompression.
- Trial name
- NCT02254590
- Testing
- Irrigation Endoscopic Decompressive Laminotomy
- Volunteers
- 104 people
- Sponsor
- Cairo University
Drain Tube Influence the Postoperative Epidural Haematoma
Does a Drain Tube Influence the Postoperative Epidural Haematoma for Lumbar Biportal Endoscopic Surgery?
The purpose of this study was to evaluate if wound drains could influence postoperative spinal epidural hematoma (POSEH) in biportal endoscopic spinal surgery (BESS) procedures for decompression of lumbar spinal stenosis.
- Trial name
- NCT06290791
- Testing
- two level lumbar decompression with BESS procedure received one drain., two level lumbar decompression with BESS procedure received two drain.
- Where
- China
- Volunteers
- 89 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Post-Operative Pain, Lumbar Laminectomy
HTX-011 in Spinal Surgery
This is a Phase 2, multicenter study in subjects undergoing an open lumbar decompression surgery.
- Trial name
- NCT04911062
- Testing
- Bupivacaine HCI without epinephrine, HTX-011, Luer Lock Applicator
- Where
- 12 sites in United States
- Volunteers
- 32 people
- Sponsor
- Heron Therapeutics
Laminectomy
Esmolol Infusion During Laminectomy: Effect on Quality of Recovery
The purpose of this study is to evaluate the effects of esmolol, a drug which is commonly administered during surgery to help control blood pressure and heart rate, on postoperative pain levels and requirements for pain…
- Trial name
- NCT01179113
- Testing
- Esmolol, Saline
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Cedars-Sinai Medical Center
Cervical Spondylosis Symptomatic Neurological Compression
Collar Immobilization Following a Posterior Cervical Laminectomy and Fusion
Cervical collars are commonly used to provide external immobilization after elective Posterior Cervical Laminectomy and Interbody Fusion (PCLIF).
- Trial name
- NCT01383876
- Testing
- Collar, No Collar
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Brigham and Women's Hospital
Postoperative Pain, Postoperative Laminectomy Pain
Postoperative Analgesia in Laminectomy
Compare the analgesic effects of naproxen sodium codeine, paracetamol codeine and placebo on postoperative pain and tramadol (Contramal) consumption during the first 24 hour after a lumbar disk surgery.
- Trial name
- (PAL) (NCT02255955)
- Testing
- 550 mg naproxen sodium and 30mg codeine, 300 mg paracetamol and 30 mg codeine
- Volunteers
- 75 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Assessing Superion Clinical Endpoints vs. Decompression
PURPOSE: The primary purpose of this study is to demonstrate that the Composite Clinical Success of the study group receiving the Superion® IDS is not inferior to the success rate observed in the study group treated by direct…
- Trial name
- ASCEND (NCT03048955)
- Testing
- Superion® IDS, Direct decompression Surgery
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VertiFlex, Incorporated
Spine Disease, Spinal Stenosis
CEUS For Intraoperative Spinal Cord Injury
Spinal cord injury following posterior decompression in patients suffering from chronic, cervicothoracic spinal cord compression is a known complication with multiple etiologies.
- Conditions
- Spine Disease, Spinal Stenosis, Spinal Injury, Spinal Cord Diseases
- Trial name
- NCT05530798
- Testing
- Definity Perflutren Lipid Microsphere Ultrasound Contrast
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia
Dysphagia and Dysphonia in Anterior Cervical Spinal Surgery
Introduction: The anterior cervical approach is used to treat a variety of spinal disorders; among these, the Smith-Robinson approach is the most commonly used, as it allows access to discs, bony structures, and anterior lesions…
- Conditions
- Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia, Anterior Cervical Spinal Surgery
- Trial name
- NCT07713693
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, 30-item questionnaire designed to assess the impact of speech dysfunction on the patient's daily life, EAT-10 questionnaire
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Spinal Stenosis, Spinal Cord Compression
Comparative Effectiveness of Microdecompression and Laminectomy for Central Lumbar Spinal Stenosis
Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis.
- Trial name
- NCT02006901
- Testing
- microdecompression, laminectomy
- Where
- Norway
- Volunteers
- 721 people
- Sponsor
- St. Olavs Hospital