Clinical trials: Spinal Hypotension
Hypotension
Up-Down Determination of the ED90 of Metaraminol to Treat Hypotension During Cesarean Section
The purpose of this study is to find the best dose of metaraminol to be used in patients during elective cesarean sections.
- Trial name
- NCT01108874
- Testing
- Metaraminol
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Hypotension
Management Arterial Hypotension During Planned Caesarean Section, Intravenous Ephedrine/Phenylephrine Mixture Versus Intravenous Baby Noradrenaline
Comparison of two practices of obstetrical services between the CHU of Clermont Ferrand and the HFME Lyon-Bron in the management of arterial hypotension during an elective cesarean section
- Trial name
- ARTEMIS (NCT05513066)
- Where
- 2 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Obstetric Anesthesia Problems, Bupivacaine Adverse Reaction
Thoraco Lumbar Vertebral Length and Bupivacaine Dosage in C-Section
Our hypothesis is that the bupivacaine dose determined according to the thoracolumbar vertebral body length (VBL) is more effective in achieving a lower hypotension rate during spinal anesthesia for cesarean delivery than the…
- Trial name
- bupivacaine (NCT06869434)
- Testing
- Group VBL (Thoracolumbal vertebral body length) received 0.2 mg x VBL cm of %0.5 hyperbaric bupivacaine, Group FD (fixed dose) received a volume of 0.5% hyperbaric bupivacaine based on a dose calculated according to the patient's height 0.065 mg/cm, Group AD (adjusted dosage) got intrathecal heavy bupivacaine (0.5%) tailored to the patient's height and weight.
- Where
- Turkey (Türkiye)
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Post Spinal Anaesthesia Hypotension, Inferior Vena Cava Collapsibility Index
Inferior Vena Cava Collapsibility Index Assessment in Predicting Post Spinal Anaesthesia Hypotension in Patients Undergoing Arthroscopic Knee Surgeries.
The aim of this study was to evaluate the role of inferior vena cava collapsibility index assessment in predicting post spinal anaesthesia hypotension in patients undergoing arthroscopic knee surgeries.
- Trial name
- NCT06767033
- Testing
- Ultrasound Guided Inferior Vena Cava Collapsibility Index Assessment
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Spinal Induced Hypotension in Cesarean Delivery
Minimum Effective Volume of Crystalloid Co-Loading to Prevent Spinal Anesthesia-Induced Hypotension in Cesarean Section
The goal of this clinical trial is to find the minimum effective volume of IV crystalloid that should be given with phenylephrine to prevent hypotension caused by spinal anesthesia in healthy, term pregnant adults having elective…
- Trial name
- NCT07324512
- Testing
- Intravenous Crystalloid Co-Loading
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Caesarian Section
Effect of Preoperative Dexamethasone in Preventing Spinal Hypotension In Patients Undergoing Elective Caesarian Section
The goal of this clinical trial is to learn whether giving a single dose of intravenous dexamethasone before spinal anesthesia can help prevent low blood pressure (spinal hypotension) in pregnant women undergoing elective…
- Trial name
- NCT07761585
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
TURP(Transurethral Resection of Prostate), Spinal Anesthesia
Modified Saddle Block vs Spinal Anesthesia for TURP
After obtaining informed consent, eligible patients will be enrolled in the study. Standard monitoring will be applied in the operating room and baseline blood pressure and heart rate will be recorded.
- Conditions
- TURP(Transurethral Resection of Prostate), Spinal Anesthesia, Saddle Block Anesthesia, Hypotension During Surgery
- Trial name
- NCT07841184
- Testing
- Saddle block, Spinal Anesthesia (bupivacaine)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Hypotension, Nausea
Ideal Dose of Phenylephrine to Treat Low Blood Pressure During Cesarean Section
The purpose of this study is to determine the minimum effective bolus dose of phenylephrine to prevent post-spinal hypotension in Cesarean section in 95 % of our patients.
- Trial name
- NCT00379691
- Testing
- phenylephrine
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Hypotension
Dexamethasone Blunts the Hypotensive Effect of Spinal Anesthesia in Geriatric Patients Undergoing Lower Limb Orthopedic Surgeries
Based on the data that DEX increases the TPR and may decrease the expression of serotonin the investigator conducted this study to test the hypothesis that the prophylactic intravenous infusion (IVI) of DEX can attenuate the…
- Trial name
- NCT03664037
- Testing
- Dexamethasone phosphate
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Orthostatic Hypotension, Spinal Cord Injuries
A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.
The purpose of this study is to determine how blood pressure and blood flow are controlled during head-up tilt in a semi-upright position.
- Trial name
- NCT00248807
- Testing
- 1.25 mg enalaprilat IV, Head up tilt (HUT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
The purpose of the study is to determine if norepinephrine is more effective as a continuous intravenous (IV) infusion compared to continuous IV ephedrine associated with crystalloid loading for maintaining blood pressure during…
- Conditions
- Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension, Complications; Cesarean Section
- Trial name
- NCT02477501
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Cesarean Section, Hypotension Drug-Induced
Bupivacaine 5 mg vs 7.5 mg for Spinal Anesthesia in Cesarean Delivery in Indonesian Population
This study aims to evaluate the efficacy of hyperbaric 5 mg bupivacaine + fentanyl 25 mcg versus hyperbaric 7.5 mg bupivacaine + fentanyl 25 mcg to lower incidence of hypotension
- Conditions
- Cesarean Section, Hypotension Drug-Induced, Spinal Anesthesia, Postoperative Complications
- Trial name
- NCT03834454
- Testing
- Bupivacaine
- Where
- Indonesia
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Hypotension Drug-Induced
Norepinephrine Addition in Spinal Anesthesia of Caesarean Section
The objective is to compare efficacy of prophylactic norepinephrine bolus versus Infusion in prevention of hypotension which occurs frequently after spinal anesthesia for caesarean section.
- Trial name
- NASA (NCT03626454)
- Testing
- Norepinephrine Bolus, Norepinephrine infusion, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Anesthesia, Spinal, Anesthesia, Obstetrical
The Effect of Injection Rate of Local Anesthetic in Caesarean Section
This randomized double-blind study aimed to compare the effects of two different subaracnoid lokal anesthetic injection rate in cesarean section. Totally 67 patients were included.
- Trial name
- NCT05091294
- Testing
- Local anesthetic injection rate in spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
HYPOTENSION AFTER SPINAL ANESTHESIA,IN PREGNANCY
EFFECT OF DIFFERENT NOREPINPHRINE APPLICATION METHODS IN CAESARIANES ON HYPOTENSION AFTER SPINAL ANESTHESIA
There are previous studies in which norepinephrine was administered only as a prophylactic or only infusion to prevent hypotension after spinal anesthesia in cesarean sections.
- Trial name
- NCT04951167
- Testing
- Norepinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Inonu University
Hypotension
Transcutaneous Electrical Acupoint Stimulation (TEAS) on Prevention Hypotension in Elderly
Despite prophylactic measures, hypotension remains a common side-effect of spinal anesthesia. Electroacupuncture influences hemodynamics.
- Trial name
- NCT05272033
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Hypotension
Norepinephrine To Prevent Hypotension After Spinal Anesthesia For Cesarean Delivery: A Dose Finding Study
Spinal anesthesia is the most common anesthetic technique for elective Cesarean delivery (CD), but the most frequent unwanted side effect is hypotension, which can cause nausea and vomiting, as well as effects on the fetus.
- Trial name
- NCT02654847
- Testing
- Norepinephrine, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anesthesia, Adverse Effect
Comparison of Two Doses of Norepinephrine in Preventing Hypotension After Spinal Anesthesia
The purpose of the study is to determine the more effective intravenous bolus of norepinephrine for maintaining blood pressure during a spinal anesthesia for a cesarean delivery with the fewer side effects.
- Conditions
- Anesthesia, Adverse Effect, Hypotension, Cesarean Section Complications
- Trial name
- NCT03706755
- Testing
- Norepinephrine: 1mcg/kg, Norepinephrine 0,5mcg/kg
- Where
- Tunisia
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar