Clinical trials: Spinal Nerve Root Disorder Nos
Lumbar and Other Intervertebral Disc Disorders With Radiculopathy
Epidural Clonidine for Lumbosacral Radiculopathy
This was a randomized, blinded study of transforaminal epidural injection of clonidine versus a similar injection of corticosteroid for acute lumbosacral radiculopathy.
- Trial name
- NCT00588354
- Testing
- Clonidine, Triamcinolone hexacetonide, Lidocaine HCl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lumbar Radiculopathy
The Effectiveness of Pain Neuroscience Education in At-risk Patients Following Surgery for Lumbar Radiculopathy
This study aims to assess the effectiveness of perioperative pain neuroscience education (PPNE) in patients who are at risk for unfavorable outcome following surgery for lumbar radiculopathy.
- Trial name
- B²EARS (NCT05047679)
- Testing
- Perioperative Pain Neuroscience Education, Perioperative Biomedical Education
- Where
- 4 sites in Belgium
- Volunteers
- 6 people
- Sponsor
- Vrije Universiteit Brussel
Lumbar Radiculopathy
Erector Spinae Block for Spine Surgery
This study is to determine whether or not the addition of liposomal bupivacaine in an ESP block will have long term benefits for patients undergoing lumbar spinal fusion surgery.
- Trial name
- NCT05417113
- Testing
- Liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Lumbar Radiculopathy
Comparative Effects Between ELDOA and Spinal Mobilization With Limb Movement in Lumbar Radiculopathy
This study examines the comparative effects of ELDOA and Spinal Mobilization with Leg Movement (SMWLM) on lumbar radiculopathy
- Trial name
- NCT07328282
- Testing
- ELDOA, Spinal Mobilization with Limb Movement - SMWLM
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Cervical Radiculopathy, Cervical Spondylosis
Transcutaneous Auricular Vagus Nerve Stimulation Combined With Cervical Epidural Injection for Cervical Radiculopathy
This is a prospective, randomized, double-blinded, sham-controlled trial conducted to investigate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) combined with cervical epidural injection in…
- Conditions
- Cervical Radiculopathy, Cervical Spondylosis, Radicular Pain
- Trial name
- NCT07557823
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Cervical Epidural Injection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Trigger Point Pain, Myofascial, Lumbar Radiculopathy
The Effect of the Presence of Active Trigger Points in the Muscles Innervated by the Affected Nerve Roots on the Treatment Results of Transforaminal Epidural Steroid Injection in Patients With Lumbar Radiculopathy.
The association between lumbosacral radiculopathy and the ipsilateral gluteal trigger point has been demonstrated in 74% of previous studies in patients with chronic low back pain.
- Trial name
- NCT05535010
- Testing
- Transforaminal epidural steroid injection(TFESI)
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Marmara University
Encephalopathy, HIV Infections
A Phase I/II Pilot Treatment Study Of CSF Penetration And Response To Ganciclovir And Foscarnet In CMV Neurologic Disease.
To determine the safety and CSF penetration of combined ganciclovir and foscarnet treatment for presumed cytomegalovirus encephalitis or radiculomyelopathy.
- Conditions
- Encephalopathy, HIV Infections, Radiculitis
- Trial name
- NCT00000856
- Testing
- Foscarnet sodium, Ganciclovir
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis
- Trial name
- NCT05029726
- Testing
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- John O'Toole
Lumbar Radiculopathy
Comparative Effects of Maitland's Rotation Mobilization and Mulligan's Spinal Mobilization With Leg Movement on Lumbar Radiculopathy
This study is a randomized control trial and the purpose of this study is to investigate and compare the effects of Maitland's rotation mobilization and Mulligan's spinal mobilization with leg movement (SMWLM) on lumbar…
- Trial name
- NCT07050966
- Testing
- Group A (Active Comparator) 1. Mulligan's Spinal Mobilization with Leg Movement (SMWLM) 2.Lower Limb Neurodynamic Mobilization, Group B (Experimental) 1. Maitland's Lumbar Rotation Mobilization 2.Lower Limb Neurodynamic Mobilization
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Foundation University Islamabad
Visual Analogue Pain Scale, Pain Measurement
Efficacy of Radiofrequency Nucleoplasty and Targeted Disc Decompression in Lumbar Radiculopathy
The aim of this study is to compare early and long term efficacy of lumbar radiofrequency nucleoplasty and targeted disc decompression in patients with lumbar radiculopathy who failed previous conventional therapy.
- Trial name
- RFNaTDD (NCT02025283)
- Testing
- Group Decompression or Group Nucleoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Ankara University
Acute Sciatica
A Comparative Effectiveness Randomised Placebo Controlled Pilot Trial of the Management of Acute Lumbar Radicular Pain
Aim: In subjects with acute sciatica (≤ 4 weeks duration), this is a pilot comparative effectiveness study to evaluate feasibility and to determine final sample size for a future adequately powered randomised controlled trial of…
- Trial name
- SCIATICA (NCT03240783)
- Testing
- Betamethasone OR Dexamethasone Injectable, Normal Saline Flush, 0.9% Injectable Solution, Dexamethasone Oral Tablet
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- St George Hospital, Australia
Contained Cervical Disc Herniation
Is Treatment of the Intervertebral Disc More Effective at Short-term Than the Nerve Root in Patients With a Neck Hernia?
Pain management in a neck hernia relies initially on rest, physiotherapy, and/or oral medications. Once these treatments have failed, different alternative procedures can be applied to relief pain.
- Trial name
- NCT01797172
- Testing
- Percutaneous Cervical Nucleoplasty, Pulsed Radio Frequency
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Willy Halim
Cervical Radiculopathy
Oral Dexamethasone for the Treatment of Cervical Radiculopathy
The purpose of this study is to determine whether dexamethasone is effective in the treatment of pain and disability resulting from a compressed spinal nerve in the neck (cervical radiculopathy).
- Trial name
- NCT00308594
- Testing
- Dexamethasone
- Volunteers
- 100 people
- Sponsor
- University of Manitoba
Rotator Cuff Tears
The Impact of Cervical Radiculopathy on Functionality in Patients Undergoing Rotator Cuff Repair
The aim of the study is to evaluate the impact of cervical radiculopathy on functional status and quality of life outcomes in patients who have undergone rotator cuff repair, comparing the group with a history of cervical…
- Trial name
- NCT07001566
- Testing
- There was no intervention. Only assessment procedure will be performed.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Lumbar Radiculopathy, Low Back Pain
Spinal Mobilization With Leg Movement Versus Neurodynamic Mobilization in Lumbar Radiculopathy
Low back pain with lumbar radiculopathy is a common condition that significantly affects functional ability and quality of life. Manual therapy is widely used as a first-line treatment to reduce pain and improve mobility.
- Trial name
- NCT07524686
- Testing
- Spinal Mobilization With Leg Movement, Neurodynamic Mobilization
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Deraya University
Sciatica, Sciatica Due to Intervertebral Disc Disorder
Transforaminal Epidural Injection in Acute Sciatica
Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery.
- Conditions
- Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy
- Trial name
- TEIAS (NCT03924791)
- Testing
- Lidocaine, Methylprednisolone Acetate, Dexamethasone
- Where
- 2 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- C.L.A.Vleggeert-Lankamp
Multilevel Cervical Spinal Stenosis, Single Brachial Radiculopathy
Head-neck Coordination Analysis After Minimally Invasive Surgery in the Dorsal Cervical Spine
To proof patients' benefit of minimally invasive surgery in the dorsal cervical spine an apparatus to examine head-neck-coordination was constructed.
- Trial name
- MISDCS (NCT01988259)
- Testing
- Bilateral approach for Laminoplasty, Unilateral approach for laminoplasty, Subperiosteal approach for foraminotomy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Schoen Klinik Hamburg Eilbek
Lumbar Degenerative Disease, Lumbar Radiculopathy
Comparison of Clinical Effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in Patients With Lumbar Disc Herniation
The goal of this clinical trial is to compare the clinical effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in patients aged 18-85 with single-level lumbar disc herniation who have not undergone…
- Conditions
- Lumbar Degenerative Disease, Lumbar Radiculopathy, Sciatic Leg Pain, Sciatic Nerve Compression
- Trial name
- NCT06615518
- Testing
- FELD (Full-Endoscopic Lumbar Discectomy), comprising IELD and TELD as anatomical subgroups, Microdiscectomy
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- University of Opole
Lumbar Radiculopathy
Study of the Diagnostic Accuracy of the Neurodynamic Tests in Patients With Lumbar Radiculopathy
Lumbar radiculopathy is a relevant cause of disability and morbidity, accounting for between 23 and 57% of the cases of patients with low back pain and representing a significant expense due to the sick leave and health care that…
- Trial name
- NCT05636917
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Cervical Radiculopathy, Home Based Rehabilitation
Home-Based Exercise After Cervical Epidural Steroid Injection for Cervical Radiculopathy
Cervical radiculopathy is a common cause of neck and arm pain resulting from compression or inflammation of a cervical nerve root.
- Trial name
- CESI-HEP (NCT07506785)
- Testing
- Cervical Interlaminar Epidural Steroid Injection, Home-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University