Lumbar RadiculopathyNCT07524686
Spinal Mobilization With Leg Movement Versus Neurodynamic Mobilization in Lumbar Radiculopathy
A study testing Spinal Mobilization With Leg Movement and Neurodynamic Mobilization in people with Lumbar Radiculopathy and Low Back Pain, run by Deraya University at 1 site in Egypt.
Trial summary
Low back pain with lumbar radiculopathy is a common condition that significantly affects functional ability and quality of life. Manual therapy is widely used as a first-line treatment to reduce pain and improve mobility. Read more about this study
- Who is it for?
- Ages 25 to 50 years
- Conditions the study is for
- Lumbar Radiculopathy, Low Back Pain
- What is being tested?
- Spinal Mobilization With Leg Movement and Neurodynamic Mobilization
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- 1 siteEgypt
- Study dates
- 10 Oct 2025to 31 Jan 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age between 25 and 50 years
- Male and female participants
- Clinically diagnosed low back pain with lumbar radiculopathy for at least 3 months
- Symptoms radiating below the knee along the sciatic nerve distribution
Who cannot join
- History of lumbar spine surgery or laminectomy
- Spinal fractures, tumors, or inflammatory disorders
- Acute disc prolapse or lumbar instability
- Lower limb vascular disease
- Neurological disorders
- Piriformis syndrome
- Manual therapy within the last 6 months
- Hip pathology or hamstring tightness
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Deraya university, faculty of physical therapy
Minya, Menia Governorate
About this study
Official title: Effectiveness of Spinal Mobilization With Leg Movement Versus Neurodynamic Mobilization in Lumbar Radiculopathy: A Randomized Controlled Trial
Low back pain with lumbar radiculopathy is a common condition that significantly affects functional ability and quality of life. Manual therapy is widely used as a first-line treatment to reduce pain and improve mobility.
This study aims to compare the effectiveness of spinal mobilization with leg movement (SMWLM) and neurodynamic mobilization in patients with lumbar radiculopathy. A total of 20 participants were randomly assigned into two groups. One group received SMWLM, while the other group received neurodynamic mobilization of the sciatic nerve over a treatment period of six weeks.
Outcomes included pain intensity, quality of life, and hip range of motion. The results of this study aim to identify the more effective intervention for improving clinical outcomes in patients with lumbar radiculopathy.
Read the detailed description
Lumbar radiculopathy is a condition characterized by low back pain radiating to the lower limb due to nerve root compression or irritation. It is associated with functional limitations, reduced mobility, and decreased quality of life.
Spinal mobilization with leg movement (SMWLM), based on the Mulligan concept, combines sustained accessory joint mobilization with active or passive limb movement. This technique aims to restore normal joint mechanics, improve spinal mobility, and reduce nerve root compression by increasing intervertebral foramen space.
Neurodynamic mobilization focuses on restoring the normal mobility and physiology of the nervous system. It involves controlled movements that mobilize neural tissues and surrounding structures, helping to reduce neural tension and improve circulation.
This randomized controlled trial compares the effectiveness of SMWLM and neurodynamic mobilization in patients with lumbar radiculopathy. Participants were randomly assigned into two groups and received treatment three times per week for six weeks.
Outcome measures included pain intensity assessed using the Visual Analog Scale (VAS), functional disability using the Oswestry Disability Index (ODI), and hip range of motion measured by a universal goniometer.
The findings of this study are expected to provide evidence-based guidance for physiotherapists in selecting optimal treatment strategies for lumbar radiculopathy.
- Conditions
- Lumbar Radiculopathy, Low Back Pain
- Being tested
- Spinal Mobilization With Leg Movement, Neurodynamic Mobilization
- Keywords
- Spinal Mobilization, Neurodynamic Mobilization, Lumbar Radiculopathy
- Medical subject headings
- Radiculopathy, Low Back Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Spinal Mobilization With Leg MovementOther
This intervention involves applying sustained accessory spinal mobilization combined with active or passive leg movement to improve joint mechanics, reduce nerve compression, and enhance mobility.
Neurodynamic MobilizationOther
Neurodynamic mobilization techniques were applied to mobilize the sciatic nerve and surrounding tissues to restore neural function, reduce tension, and improve mobility.
| Study group | Role | What they receive |
|---|---|---|
| Spinal Mobilization With Leg Movement Group | Experimental | Participants in this group received spinal mobilization with leg movement (SMWLM) based on the Mulligan concept to improve spinal mobility, reduce pain, and enhance functional performance. Receives: Other: Spinal Mobilization With Leg Movement |
| Neurodynamic Mobilization Group | Experimental | Participants in this group received neurodynamic mobilization targeting the sciatic nerve to improve neural mobility and reduce pain associated with lumbar radiculopathy. Receives: Other: Neurodynamic Mobilization |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Intensity (Visual Analogue Scale)
Pain intensity was measured using the Visual Analogue Scale (VAS), where 0 indicates no pain, and 10 indicates the worst possible pain.
Measured: Baseline and after 6 weeks of treatment
Functional Disability (Oswestry Disability Index)
Functional disability was assessed using the Oswestry Disability Index (ODI), which evaluates limitations in daily activities due to low back pain.
Measured: Baseline and after 6 weeks of treatment
Hip Range of Motion
Hip range of motion was measured using a universal goniometer to assess improvements in joint mobility.
Measured: Baseline and after 6 weeks of treatment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Apr 2026
- Study start10 Oct 2025
- Primary completion31 Jan 2026
- Study completion31 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Lumbar RadiculopathyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants were randomly assigned into two parallel groups. One group received spinal mobilization with leg movement, while the other group received neurodynamic mobilization. Outcomes were compared after completion of the intervention period.
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 20 participants (actual)
Sponsor and investigators
- Lead sponsor
- Deraya University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07524686
- Sponsor's protocol ID
- DU-FPT-LR-2025
- Status last verified
- Apr 2026
- First submitted
- 6 Apr 2026
- Last updated
- 13 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 13 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Spinal Mobilization With Leg Movement Versus Neurodynamic Mobilization in Lumbar Radiculopathy: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07524686
- Acronym / sponsor ID
- DU-FPT-LR-2025
- Conditions
- Lumbar Radiculopathy, Low Back Pain
- Keywords
- Spinal Mobilization, Neurodynamic Mobilization, Lumbar Radiculopathy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 20 participants (actual)
- Lead sponsor
- Deraya UniversityUniversity, hospital or other
- Study start
- 10 Oct 2025 (actual)
- Primary completion
- 31 Jan 2026 (actual)
- Study completion
- 31 Jan 2026 (actual)
- First posted
- 13 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Low back pain with lumbar radiculopathy is a common condition that significantly affects functional ability and quality of life. Manual therapy is widely used as a first-line treatment to reduce pain and improve mobility.
This study aims to compare the effectiveness of spinal mobilization with leg movement (SMWLM) and neurodynamic mobilization in patients with lumbar radiculopathy. A total of 20 participants were randomly assigned into two groups. One group received SMWLM, while the other group received neurodynamic mobilization of the sciatic nerve over a treatment period of six weeks.
Outcomes included pain intensity, quality of life, and hip range of motion. The results of this study aim to identify the more effective intervention for improving clinical outcomes in patients with lumbar radiculopathy.
Detailed description
Lumbar radiculopathy is a condition characterized by low back pain radiating to the lower limb due to nerve root compression or irritation. It is associated with functional limitations, reduced mobility, and decreased quality of life.
Spinal mobilization with leg movement (SMWLM), based on the Mulligan concept, combines sustained accessory joint mobilization with active or passive limb movement. This technique aims to restore normal joint mechanics, improve spinal mobility, and reduce nerve root compression by increasing intervertebral foramen space.
Neurodynamic mobilization focuses on restoring the normal mobility and physiology of the nervous system. It involves controlled movements that mobilize neural tissues and surrounding structures, helping to reduce neural tension and improve circulation.
This randomized controlled trial compares the effectiveness of SMWLM and neurodynamic mobilization in patients with lumbar radiculopathy. Participants were randomly assigned into two groups and received treatment three times per week for six weeks.
Outcome measures included pain intensity assessed using the Visual Analog Scale (VAS), functional disability using the Oswestry Disability Index (ODI), and hip range of motion measured by a universal goniometer.
The findings of this study are expected to provide evidence-based guidance for physiotherapists in selecting optimal treatment strategies for lumbar radiculopathy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
- Model description
- Participants were randomly assigned into two parallel groups. One group received spinal mobilization with leg movement, while the other group received neurodynamic mobilization. Outcomes were compared after completion of the intervention period.
| Arm | Type | Receives |
|---|---|---|
| Spinal Mobilization With Leg Movement Group | Experimental | Other: Spinal Mobilization With Leg MovementParticipants in this group received spinal mobilization with leg movement (SMWLM) based on the Mulligan concept to improve spinal mobility, reduce pain, and enhance functional performance. |
| Neurodynamic Mobilization Group | Experimental | Other: Neurodynamic MobilizationParticipants in this group received neurodynamic mobilization targeting the sciatic nerve to improve neural mobility and reduce pain associated with lumbar radiculopathy. |
Who may qualify
- Ages
- 25 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Age between 25 and 50 years
- Male and female participants
- Clinically diagnosed low back pain with lumbar radiculopathy for at least 3 months
- Symptoms radiating below the knee along the sciatic nerve distribution
Key exclusion criteria (8 listed)
- History of lumbar spine surgery or laminectomy
- Spinal fractures, tumors, or inflammatory disorders
- Acute disc prolapse or lumbar instability
- Lower limb vascular disease
- Neurological disorders
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Spinal Mobilization With Leg MovementThis intervention involves applying sustained accessory spinal mobilization combined with active or passive leg movement to improve joint mechanics, reduce nerve compression, and enhance mobility. | Other | Spinal Mobilization With Leg Movement Group |
| Neurodynamic MobilizationNeurodynamic mobilization techniques were applied to mobilize the sciatic nerve and surrounding tissues to restore neural function, reduce tension, and improve mobility. | Other | Neurodynamic Mobilization Group |
Primary outcome
Pain Intensity (Visual Analogue Scale)
Time frame: Baseline and after 6 weeks of treatment
Pain intensity was measured using the Visual Analogue Scale (VAS), where 0 indicates no pain, and 10 indicates the worst possible pain.
Functional Disability (Oswestry Disability Index)
Time frame: Baseline and after 6 weeks of treatment
Functional disability was assessed using the Oswestry Disability Index (ODI), which evaluates limitations in daily activities due to low back pain.
Hip Range of Motion
Time frame: Baseline and after 6 weeks of treatment
Hip range of motion was measured using a universal goniometer to assess improvements in joint mobility.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Apr 2026.
- Individual participant dataSharing planned: No
Related trials for Lumbar Radiculopathy
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Spinal Mobilization With Leg Movement and Neurodynamic Mobilization in people with Lumbar Radiculopathy and Low Back Pain, run by Deraya University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Intensity (Visual Analogue Scale) (time frame: Baseline and after 6 weeks of treatment). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Apr 2026.