Clinical trials: Spinal Nerve Root Disorder Nos
Adjacent Segment Disease, Cervical Myelopathy
Adjacent Segment Disease After Anterior Cervical Decompression Surgery
Radiculopathy and/or myelopathy due to cervical degenerative disc disease are increasingly common pathologies in our ageing population. Both can be treated non-surgically or surgically.
- Conditions
- Adjacent Segment Disease, Cervical Myelopathy, Cervical Radiculopathy, Degenerative Disc Disease
- Trial name
- ASDafterACDF (NCT04320043)
- Testing
- Anterior cervical decompression
- Where
- Netherlands
- Volunteers
- 673 people
- Sponsor
- Zuyderland Medisch Centrum
Headache, Cervical Radiculopathy
Outcomes After Surgery for Degenerative Cervical Radiculopathy in Patients with Concurrent Headache
Surgery for degenerative cervical radiculopathy (DCR) is one of the most common causes of neck surgery. The typical surgical indication is radicular pain (arm pain) caused by nerve impingement.
- Trial name
- NCT06885216
- Testing
- Anterior cervical discectomy and fusion/ posterior decompression
- Volunteers
- 12,000 people
- Sponsor
- University Hospital of North Norway
Radiculopathy, Cervical Region, Neck Pain
Predictors of Clinical Response After Interlaminar Cervical Epidural Steroid Injection for Cervical Radiculopathy
Cervical epidural steroid injection is a commonly used treatment option for patients with cervical radicular pain who do not improve adequately with conservative treatment.
- Conditions
- Radiculopathy, Cervical Region, Neck Pain, Disc Disease, Radicular Pain
- Trial name
- M-DICER (NCT07535476)
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Mersin University
Cervical Radiculopathy
Efficacy Of Gross Myofascial Release With Neural Mobilization Versus Neural Mobilization Alone On Pain, Functional Limitations, And Cervical Range Of Motion In Cervical Radiculopathy
This is a randomized control trial aims to evaluate the efficacy of gross myofascial release with neural mobilization versus neural mobilization alone on pain, functional limitations, and cervical range of motion in cervical…
- Trial name
- NCT07808476
- Testing
- Gross Myofascial Release + Neural Mobilization, Neural Mobilization
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Ibadat International University, Islamabad
Prevalence, Lumbosacral Radiculopathy
Prevalenc Of Lumbosacral Radiculopathy Among Physiotherapists Of Pediatric Rehabilitation OF PEDIATRIC REHABILITATION
Determine the prevalence of lumbosacral radiculopathy among pediatric physiotherapists in the ministry of health in Cairo, Egypt.
- Trial name
- NCT06335732
- Testing
- Cross section study; single group related measurement design.
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kerolous Ishak Shehata
Radiculopathy Lumbar, Radiculopathy, Lumbosacral Region
Radiofrequency for Chronic Radicular Lumbar Pain: Geriatric vs. Young Patients
This study aims to evaluate the treatment response and lumbar magnetic resonance imaging (MRI) findings of patients who have undergone pulsed radiofrequency therapy for chronic radicular lumbar pain at the dorsal root ganglia.
- Conditions
- Radiculopathy Lumbar, Radiculopathy, Lumbosacral Region, Chronic Pain
- Trial name
- NCT06903949
- Testing
- Lumbar Dorsal Root Ganglia Pulsed Radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ankara Etlik City Hospital
Radiculopathy, Herniated Disc
Regenexx™ PL-Disc Versus Steroid Epidurals for Lumbar Radiculopathy
The primary objective of this study is to compare the improvement in subject-reported clinical outcomes for Regenexx PL-Disc vs.
- Conditions
- Radiculopathy, Herniated Disc, Disc Degeneration
- Trial name
- NCT01850771
- Testing
- Regenexx PL-Disc, Steroid Epidural
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Regenexx, LLC
Cervical Disc Degeneration
Real World Data Collection on the Synergy Cervical Disc
This trial is a real world data (RWD) collection observational study, comprised of both prospective and retrospective arms, that will examine the safety and effectiveness of the Synergy Cervical Disc System in patients with…
- Trial name
- NCT05305430
- Testing
- Synergy Cervical Disc System
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Synergy Spine Solutions
Lumbosacral Radiculopathy
Sciatica Epidural Radiculopathy Experimental New Interventional TherapY Clonidine Micropellet
This study will evaluate the safety and effectiveness of a new pain medication in development, clonidine micropellet. Participants will receive a single injection of either clonidine micropellet or sham injection for the…
- Trial name
- SERENITY CM (NCT05614648)
- Testing
- Clonidine Micropellets, Tuohy epidural needle
- Where
- 30 sites in United States
- Volunteers
- 17 people
- Sponsor
- Sollis Therapeutics, Inc.
Radiculopathy Lumbar, Radiculopathy Sacral
The Selective Intraperineural Nerve Root Block Study
Before lumbosacral decompression surgery for radicular pain, selective nerve root block(SNRB) is a common procedure to identify the responsible compressed nerve root(RCNR) and predict surgical outcomes.
- Conditions
- Radiculopathy Lumbar, Radiculopathy Sacral, Radiculopathy Multiple Sites, Herniated Disc
- Trial name
- SINRBS (NCT07531485)
- Testing
- Selective Intraperineural Nerve Root Block(SINRB), single-level lumbar decompression surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xi'an Honghui Hospital
Cervical Radiculopathy
Effect of HPLT on Pain and Electrophysiological Study in Cervical Radiculopathy Patients
The goal of this clinical trial is : To determine the effect of high power laser therapy on pain and electrophysiological study in patients with cervical radiculopathy.
- Trial name
- NCT05852613
- Testing
- high power laser therapy (HPLT), selected physical therapy program
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Lumbar Disc Herniation, Radiculopathy Lumbar
The Effect of Ultrasound Guidance on Radiation Dose and Procedure Time in Lumbar Transforaminal Epidural Injection
Low back pain is one of the leading causes of disability, and its social burden and economic cost are quite high. Although there are many causes that can lead to low back pain, radicular pain, which develops mostly secondary to…
- Trial name
- NCT05793528
- Testing
- Fluoroscopy Guided Transforaminal Epidural Steroid Injection, Ultrasound Guided Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Sciatica Acute
Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care
The goal of this clinical trial is to compare transgluteal sciatic nerve block to standard of care to treat sciatic back pain in adult patients who present to the emergency department.
- Trial name
- TGSNB vs SoC (NCT07397117)
- Testing
- nerve block with ropivacaine, Standard medical treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Cervical Radiculopathy
Does Low-does Cervical Epidural Lidocaine Cause Transient Weakness?
"Does low-does cervical epidural lidocaine cause transient weakness?"
- Trial name
- NCT03382925
- Testing
- cervical interlaminar with lidocaine, cervical interlaminar with normal saline, Lidocaine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Utah
Cervical Degenerative Disc Disease, Cervical Radiculopathy
M6-C Post Approval Study (PAS)
The M6-C Post Approval Study is a long term follow-up study of subjects previously enrolled and treated in the M6-C Artificial Cervical Disc IDE Study.
- Conditions
- Cervical Degenerative Disc Disease, Cervical Radiculopathy, Cervical Spinal Cord Compression, Cervical Disc Herniation
- Trial name
- NCT04122248
- Testing
- standard radiographic imaging, cervical total disc replacement
- Where
- 21 sites in United States
- Volunteers
- 152 people
- Sponsor
- Spinal Kinetics
Low Back Pain, Multifidus
Effects of Isolated Lumbar Extension Resistance Training Alone and in Combination with General Exercise and Manual Therapy
This study examines effects of machine-based isolated lumbar extension resistance exercise (ILEX) on paraspinal muscle morphology and function, as well as pain intensity, disability and quality of life in patients with chronic…
- Conditions
- Low Back Pain, Multifidus, Exercise Therapy, Diagnostic Imaging
- Trial name
- NCT06890052
- Testing
- Targeted exercise program, Targeted exercise as part of an integrative therapy program
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Low Back Pain, Neck Pain
Pre-Visit AI Symptom-Checking and Shared Decision-Making in Spine Physical Therapy
Artificial intelligence (AI) symptom-checking tools, including large language models such as ChatGPT, are increasingly used by patients before they seek care.
- Conditions
- Low Back Pain, Neck Pain, Radiculopathy
- Trial name
- NCT07733752
- Testing
- re-visit AI symptom-checker use
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Cervical Radiculopathy
ELECTROMAGNETIC FIELD ON NECK PAIN AND PROPRIOCEPTION IN CERVICAL RADICULOPATHY
PURPOSE: to investigate effect of electromagnetic field therapy on neck pain and proprioception in cervical radiculopathy patients BACKGROUND: Cervical radiculopathy is a clinical condition resulting from compression of cervical…
- Trial name
- NCT05332418
- Testing
- selected exercise program, Electromagenetic Field therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Cervical Radiculopathy, Degenerative Disc Disease
Restore CLINICAL TRIAL
This is a prospective, concurrently controlled, multi-center study to evaluate the safety and effectiveness of the Spinal Kinetics M6-C artificial cervical disc compared to anterior cervical discectomy and fusion (ACDF) for the…
- Trial name
- NCT01609374
- Testing
- M6-C Artificial Cervical Disc, Anterior plate system with corticocancellous allograft bone
- Volunteers
- 258 people
- Sponsor
- Spinal Kinetics
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital